scholarly journals High spatial and temporal resolution dynamic contrast-enhanced magnetic resonance angiography using compressed sensing with magnitude image subtraction

2013 ◽  
Vol 71 (5) ◽  
pp. 1771-1783 ◽  
Author(s):  
Stanislas Rapacchi ◽  
Fei Han ◽  
Yutaka Natsuaki ◽  
Randall Kroeker ◽  
Adam Plotnik ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Compressed Sensing ◽  
Temporal Resolution ◽  
Image Subtraction ◽  
Magnitude Image ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced

DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE ANGIOGRAPHY OF Gd-TTDA-BOM COMPARED WITH Gd-DTPA IN NORMAL RAT AT 3T

2014 ◽  
Vol 26 (02) ◽  
pp. 1450027
Author(s):  
Jo-Chi Jao ◽  
Yen-Ku Chen ◽  
Twei-Shiun Jaw ◽  
Yun-Ming Wang ◽  
Po-Chou Chen
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Vascular Diseases ◽  
Signal Enhancement ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced ◽  
Normal Rat ◽  
Reorientation Time ◽  
Phantom Studies

Dynamic contrast-enhanced magnetic resonance angiography (DCE-MRA) is a good modality for the diagnosis of vascular diseases. Contrast agents that produce higher and longer enhancement in vessels are highly valued. The complex of gadolinium with (R,S)-4-carboxy-5,9,12-tris(carboxymethyl)-l-phenyl-2-oxa-5,9,12-triazatridecan-14-oic acid (Gd-TTDA-BOM) possesses a benzyloxymethyl group in the ligand TTDA-BOM with the capability of raising lipophilicity. The Gd-TTDA-BOM complex expresses higher and longer enhancement in mouse liver than that of gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) because of its faster water exchange rate, higher reorientation time, and higher lipophilicity. Phantom studies have shown that Gd-TTDA-BOM has expressed with higher affinity to human serum albumin (HSA) than Gd-DTPA. In general, these characteristics might provide an advantage for vascular imaging. To verify this in vivo, a 3T MR scanner was used to investigate the signal enhancement in the aorta of normal rats by DCE-MRA after the bolus injection of Gd-TTDA-BOM and compared this with the injection of Gd-DTPA. Gd-TTDA-BOM expressed higher and longer signal enhancement in the aorta than Gd-DTPA. These results suggest that Gd-TTDA-BOM could provide better image quality than Gd-DTPA as an enhancement agent in DCE-MRA.

Dynamic Contrast-Enhanced Magnetic Resonance Angiography of the Thoracic Vessels

2010 ◽  
Vol 45 (11) ◽  
pp. 708-714 ◽  
Author(s):  
Katja Seng ◽  
Stefan Maderwald ◽  
Armin de Greiff ◽  
Harald H. Quick ◽  
Gerhard Laub ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced
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