High-resolution cerebral blood volume imaging in humans using the blood pool contrast agent ferumoxytol

2012 ◽  
Vol 70 (3) ◽  
pp. 705-710 ◽  
Author(s):  
Thomas Christen ◽  
Wendy Ni ◽  
Deqiang Qiu ◽  
Heiko Schmiedeskamp ◽  
Roland Bammer ◽  
...  
Keyword(s):  
High Resolution ◽  
Contrast Agent ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Blood Pool ◽  
Blood Pool Contrast Agent ◽  
Volume Imaging

Contribution of Sinerem® used as blood-pool contrast agent: Detection of cerebral blood volume changes during apnea in the rabbit

1996 ◽  
Vol 36 (3) ◽  
pp. 415-419 ◽  
Author(s):  
Isabelle Berry ◽  
Soraya Benderbous ◽  
Jean-Philippe Ranjeva ◽  
Dominique Gracia-Meavilla ◽  
Claude Manelfe ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Blood Pool ◽  
Volume Changes ◽  
Blood Pool Contrast Agent

scholarly journals High-resolution magnetic resonance angiography in the mouse using a nanoparticle blood-pool contrast agent

2009 ◽  
Vol 62 (6) ◽  
pp. 1447-1456 ◽  
Author(s):  
Gabriel P. Howles ◽  
Ketan B. Ghaghada ◽  
Yi Qi ◽  
Srinivasan Mukundan ◽  
G. Allan Johnson
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Magnetic Resonance Angiography ◽  
Contrast Agent ◽  
Blood Pool ◽  
Blood Pool Contrast Agent

scholarly journals Ultra High-Resolution In vivo Computed Tomography Imaging of Mouse Cerebrovasculature Using a Long Circulating Blood Pool Contrast Agent

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Zbigniew Starosolski ◽  
Carlos A. Villamizar ◽  
David Rendon ◽  
Michael J. Paldino ◽  
Dianna M. Milewicz ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Contrast Agent ◽  
Blood Pool ◽  
Computed Tomography Imaging ◽  
Blood Pool Contrast Agent ◽  
Tomography Imaging

scholarly journals Basal Cerebral Blood Volume during the Poststimulation Undershoot in BOLD MRI of the Human Brain

2010 ◽  
Vol 31 (1) ◽  
pp. 82-89 ◽  
Author(s):  
Peter Dechent ◽  
Gunther Schütze ◽  
Gunther Helms ◽  
Klaus Dietmar Merboldt ◽  
Jens Frahm
Keyword(s):  
Contrast Agent ◽  
Blood Volume ◽  
Animal Studies ◽  
Cerebral Blood Volume ◽  
Visual Stimulation ◽  
Three Dimensional ◽  
Blood Pool ◽  
Blood Oxygenation ◽  
Bold Mri ◽  
Oxygenation Level

One of the characteristics of the blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) response to functional challenges of the brain is the poststimulation undershoot, which has been suggested to originate from a delayed recovery of either cerebral blood volume (CBV) or cerebral metabolic rate of oxygen to baseline. Using bolus-tracking MRI in humans, we recently showed that relative CBV rapidly normalizes after the end of stimulation. As this observation contradicts at least part of the blood-pool contrast agent studies performed in animals, we reinvestigated the CBV contribution by dynamic T1-weighted three-dimensional MRI (8 seconds temporal resolution) and Vasovist at 3 T (12 subjects). Initially, we determined the time constants of individual BOLD responses. After injection of Vasovist, CBV-related T1-weighted signal changes revealed a signal increase during visual stimulation (1.7%±0.4%), but no change relative to baseline in the poststimulation phase (0.2%±0.3%). This finding renders the specific nature of the contrast agent unlikely to be responsible for the discrepancy between human and animal studies. With the assumption of normalized cerebral blood flow after stimulus cessation, a normalized CBV lends support to the idea that the BOLD MRI undershoot reflects a prolonged elevation of oxidative metabolism.

Dixon-based fat-free MR-angiography compared to first pass and steady-state high-resolution MR-angiography using a blood pool contrast agent

2015 ◽  
Vol 33 (9) ◽  
pp. 1035-1042 ◽  
Author(s):  
Rami Homsi ◽  
Jürgen Gieseke ◽  
Guido M. Kukuk ◽  
Frank Träber ◽  
Winfried A. Willinek ◽  
...  
Keyword(s):  
Steady State ◽  
High Resolution ◽  
Contrast Agent ◽  
Mr Angiography ◽  
Blood Pool ◽  
Blood Pool Contrast Agent ◽  
First Pass

scholarly journals Amphiphilic DTPA Multimer Assembled on Icosahedral Closo-Borane Motif as High-Performance MRI Blood Pool Contrast Agent

2021 ◽  
Author(s):  
Lalit N. Goswami ◽  
Shatadru Chakravarty ◽  
Quan-Yu Cai ◽  
Erik M. Shapiro ◽  
M. Frederick Hawthorne ◽  
...  
Keyword(s):  
Contrast Agent ◽  
High Performance ◽  
Blood Pool ◽  
Blood Pool Contrast Agent
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