A fast spectroscopic imaging method using a blipped phase encode gradient

1989 ◽  
Vol 12 (3) ◽  
pp. 306-315 ◽  
Author(s):  
Peter Webb ◽  
Daniel Spielman ◽  
Albert Macovski
Keyword(s):  
Spectroscopic Imaging ◽  
Imaging Method ◽  
Phase Encode Gradient ◽  
Phase Encode

4797616 High speed NMR spectroscopic imaging method

1990 ◽  
Vol 8 (1) ◽  
pp. V
Author(s):  
Shigeru Matsui ◽  
Takash Onodera ◽  
Kensuke Sekihara ◽  
Hidemi Shiono ◽  
Hideki Kohno
Keyword(s):  
High Speed ◽  
Spectroscopic Imaging ◽  
Imaging Method

A Multimodal Spectroscopic Imaging Method To Characterize the Metal and Macromolecular Content of Proteinaceous Aggregates (“Amyloid Plaques”)

Biochemistry ◽  
2017 ◽  
Vol 56 (32) ◽  
pp. 4107-4116 ◽  
Author(s):  
Kelly L. Summers ◽  
Nicholas Fimognari ◽  
Ashley Hollings ◽  
Mitchell Kiernan ◽  
Virginie Lam ◽  
...  
Keyword(s):  
Spectroscopic Imaging ◽  
Amyloid Plaques ◽  
Imaging Method ◽  
Macromolecular Content

scholarly journals Tissue Dynamics Spectroscopic Imaging: Functional Imaging of Heterogeneous Cancer Tissue

2020 ◽  
Author(s):  
Zhe Li ◽  
Bihe Hu ◽  
Guang Li ◽  
Sharon E. Fox ◽  
Shadia Jalal ◽  
...  
Keyword(s):  
Functional Imaging ◽  
Tumor Heterogeneity ◽  
Drug Response ◽  
Ex Vivo ◽  
Spectroscopic Imaging ◽  
Cancer Tissue ◽  
Imaging Method ◽  
Spatial Response ◽  
Chemotherapeutic Treatment ◽  
Spatial Maps

AbstractSignificanceTumor heterogeneity poses a challenge for the chemotherapeutic treatment of cancer. Tissue dynamics spectroscopy (TDS) captures dynamic contrast and can capture the response of living tissue to applied therapeutics, but the current analysis averages over the complicated spatial response of living biopsy samples.AimTo develop tissue dynamics spectroscopic imaging (TDSI) to map the heterogeneous spatial response of tumor tissue to anticancer drugs.ApproachTDSI is applied to tumor spheroids grown from cell lines and to ex vivo living esophageal biopsy samples. Doppler fluctuation spectroscopy is performed on a voxel basis to extract spatial maps of biodynamic biomarkers. Functional images and bivariate spatial maps are produced using a bivariate color merge to represent the spatial distribution of pairs of signed drug-response biodynamic biomarkers.ResultsWe have mapped the spatial variability of drug responses within biopsies and have tracked sample-to-sample variability. Sample heterogeneity observed in the biodynamic maps is associated with histological heterogeneity observed using inverted Selective-Plane Illumination Microscopy (iSPIM).ConclusionWe have demonstrated the utility of TDSI as a functional imaging method to measure tumor heterogeneity and its potential for use in drug-response profiling.

scholarly journals Elimination of Nyquist ghosting caused by read-out to phase-encode gradient cross-terms in EPI

2002 ◽  
Vol 47 (2) ◽  
pp. 337-343 ◽  
Author(s):  
Stuart M. Grieve ◽  
Andrew M. Blamire ◽  
Peter Styles
Keyword(s):  
Cross Terms ◽  
Phase Encode Gradient ◽  
Phase Encode
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