3D MR angiography of intratumoral vasculature using a novel macromolecular MR contrast agent

2001 ◽  
Vol 46 (3) ◽  
pp. 579-585 ◽  
Author(s):  
Hisataka Kobayashi ◽  
Noriko Sato ◽  
Satomi Kawamoto ◽  
Tsuneo Saga ◽  
Akira Hiraga ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography

scholarly journals Reducing Contrast Agent Dose in Cardiovascular MR Angiography with Deep Learning

2021 ◽  
Author(s):  
Javier Montalt‐Tordera ◽  
Michael Quail ◽  
Jennifer A Steeden ◽  
Vivek Muthurangu
Keyword(s):  
Deep Learning ◽  
Contrast Agent ◽  
Mr Angiography ◽  
Cardiovascular Mr

High-Spatial-Resolution Multistation MR Angiography with Parallel Imaging and Blood Pool Contrast Agent: Initial Experience

Radiology ◽  
2006 ◽  
Vol 241 (3) ◽  
pp. 861-872 ◽  
Author(s):  
Konstantin Nikolaou ◽  
Harald Kramer ◽  
Christina Grosse ◽  
Dirk Clevert ◽  
Olaf Dietrich ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Spatial Resolution ◽  
Mr Angiography ◽  
Parallel Imaging ◽  
High Spatial Resolution ◽  
Blood Pool ◽  
Initial Experience ◽  
Blood Pool Contrast Agent

scholarly journals Contrast-Enhanced Magnetic Resonance Angiography Using a Novel Elastin-Specific Molecular Probe in an Experimental Animal Model

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Carolin Reimann ◽  
Julia Brangsch ◽  
Jan Ole Kaufmann ◽  
Lisa C. Adams ◽  
David C. Onthank ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Image Quality ◽  
Magnetic Resonance Angiography ◽  
Contrast Agent ◽  
Mr Angiography ◽  
Molecular Probe ◽  
Time Resolved ◽  
Clinical Dose ◽  
Contrast Enhanced ◽  
First Pass

Objectives. The aim of this study was to test the potential of a new elastin-specific molecular agent for the performance of contrast-enhanced first-pass and 3D magnetic resonance angiography (MRA), compared to a clinically used extravascular contrast agent (gadobutrol) and based on clinical MR sequences. Materials and Methods. Eight C57BL/6J mice (BL6, male, aged 10 weeks) underwent a contrast-enhanced first-pass and 3D MR angiography (MRA) of the aorta and its main branches. All examinations were on a clinical 3 Tesla MR system (Siemens Healthcare, Erlangen, Germany). The clinical dose of 0.1 mmol/kg was administered in both probes. First, a time-resolved MRA (TWIST) was acquired during the first-pass to assess the arrival and washout of the contrast agent bolus. Subsequently, a high-resolution 3D MRA sequence (3D T1 FLASH) was acquired. Signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) were calculated for all sequences. Results. The elastin-specific MR probe and the extravascular imaging agent (gadobutrol) enable high-quality MR angiograms in all animals. During the first-pass, the probes demonstrated a comparable peak enhancement (300.6 ± 32.9 vs. 288.5 ± 33.1, p>0.05). Following the bolus phase, both agents showed a comparable intravascular enhancement (SNR: 106.7 ± 11 vs. 102.3 ± 5.3; CNR 64.5 ± 7.4 vs. 61.1 ± 7.2, p>0.05). Both agents resulted in a high image quality with no statistical difference (p>0.05). Conclusion. The novel elastin-specific molecular probe enables the performance of first-pass and late 3D MR angiography with an intravascular contrast enhancement and image quality comparable to a clinically used extravascular contrast agent.

K-space filter effect in three-dimensional contrast MR angiography

1997 ◽  
Vol 38 (1) ◽  
pp. 173-175 ◽  
Author(s):  
K. Ito ◽  
J. Kato ◽  
S. Okada ◽  
T. Kumazaki
Keyword(s):  
Contrast Agent ◽  
Data Acquisition ◽  
Mr Angiography ◽  
Three Dimensional ◽  
Mr Images ◽  
Acquisition Period ◽  
Filter Effect ◽  
Flowing Material ◽  
Space Filter

Purpose: In three-dimensional (3-D) contrast MR angiography, temporal misregistration between the data acquisition period and the arrival of the contrast agent in the target vessels is thought to degrade the quality of the reconstructed images. The purpose of this study was to demonstrate and investigate this effect in phantom experiments. Material and Methods: MR images of a phantom tube were evaluated with flowing materials of water or Gd-DTPA solution by changing from water to Gd-DTPA solution halfway through the data acquisition period. Results: While no signal could be acquired with a stream of water in the tube, a clear signal was obtained with a flow of Gd-DTPA solution. Blurring and ghost artifacts surrounding the tube along the phase-encoding direction were observed when the flowing material was changed from water to Gd-DTPA solution halfway through the data acquisition period. Conclusion: K-space filter effect occurs during 3-D contrast MR angiography owing to the transient passage of the contrast agent, and this effect causes spatial artifacts in the reconstructed images.

Correlation between dose rate and T1 in blood at gd-enhanced MR angiography

1998 ◽  
Vol 39 (5) ◽  
pp. 579-582 ◽  
Author(s):  
L. O. M. Johansson ◽  
H. K. Ahlström
Keyword(s):  
Time Delay ◽  
Contrast Agent ◽  
Dose Rate ◽  
Abdominal Aorta ◽  
Signal Intensity ◽  
Mr Angiography ◽  
Pulse Sequence ◽  
Test Dose ◽  
Contrast Enhanced ◽  
First Pass

Purpose: to determine the correlation between dose rate and T1 in blood at Gd-enhanced MR angiography (MRA) Material and Methods: A test dose of contrast agent was used to calculate the time delay between injection and arrival in the abdominal aorta. the dose rate was expressed as ml · kg b.w.−1 · s−1. the correlation between dose rate and T1 was determined by varying the dose rate while keeping the scanning and infusion times constant. the signal intensity in the abdominal aorta was measured during the first pass of Gd and compared with markers of known T1 values Results: A correlation between dose rate and T1 in blood was obtained Conclusion: A Gd dose rate of 0.01 ml · kg b.w.−1 · s−1 gives a T1 in blood of 100 ms. This can be used to calculate the optimal pulse sequence for contrast-enhanced MRA

MR Angiography of Aortoiliac Occlusive Disease: A Phase III Study of the Safety and Effectiveness of the Blood-Pool Contrast Agent MS-325

Radiology ◽  
2005 ◽  
Vol 236 (3) ◽  
pp. 825-833 ◽  
Author(s):  
Mathias Goyen ◽  
Mark Edelman ◽  
Pierre Perreault ◽  
Elaine O'Riordan ◽  
Hernan Bertoni ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography ◽  
Blood Pool ◽  
Occlusive Disease ◽  
Phase Iii ◽  
Aortoiliac Occlusive Disease ◽  
Blood Pool Contrast Agent ◽  
Phase Iii Study

Preliminary evaluation of a polyethyleneglycol-stabilized manganese-substituted hydroxylapatite as an intravascular contrast agent for MR angiography

1997 ◽  
Vol 7 (1) ◽  
pp. 204-208 ◽  
Author(s):  
Kofi Adzamli ◽  
Richard B. Dorshow ◽  
Michael R. Hynes ◽  
Debiao Li ◽  
Dennis L. Nosco ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography ◽  
Preliminary Evaluation ◽  
Intravascular Contrast Agent

Equilibrium-Phase MR Angiography of the Aortoiliac and Renal Arteries Using a Blood Pool Contrast Agent

2000 ◽  
Vol 175 (1) ◽  
pp. 189-195 ◽  
Author(s):  
Dominik Weishaupt ◽  
Stefan G. Rühm ◽  
Christoph A. Binkert ◽  
Michaela Schmidt ◽  
Michael A. Patak ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography ◽  
Equilibrium Phase ◽  
Blood Pool ◽  
Renal Arteries ◽  
Blood Pool Contrast Agent

scholarly journals Pulmonary MR angiography with contrast agent at 4 Tesla: A preliminary result

2001 ◽  
Vol 46 (5) ◽  
pp. 1028-1030 ◽  
Author(s):  
Hidemasa Uematsu ◽  
Lawrence Dougherty ◽  
Masaya Takahashi ◽  
Yoshiharu Ohno ◽  
Masashi Nakatsu ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography

scholarly journals Dynamic coronary MR angiography and first-pass perfusion with intracoronary administration of contrast agent

2002 ◽  
Vol 16 (3) ◽  
pp. 311-319 ◽  
Author(s):  
Nikolaos V. Tsekos ◽  
Pamela K. Woodard ◽  
Glenn J. Foster ◽  
Pavlos Moustakidis ◽  
Terry L. Sharp ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Mr Angiography ◽  
Pass Perfusion ◽  
Intracoronary Administration ◽  
First Pass ◽  
Coronary Mr Angiography ◽  
First Pass Perfusion
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