scholarly journals High-resolution MRI with cardiac and respiratory gating allows for accurate in vivo atherosclerotic plaque visualization in the murine aortic arch

2003 ◽  
Vol 50 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Frank Wiesmann ◽  
Michael Szimtenings ◽  
Alex Frydrychowicz ◽  
Ralf Illinger ◽  
Andreas Hunecke ◽  
...  
2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Shai Berman ◽  
Roey Schurr ◽  
Gal Atlan ◽  
Ami Citri ◽  
Aviv A Mezer

Abstract The claustrum is a thin sheet of neurons enclosed by white matter and situated between the insula and the putamen. It is highly interconnected with sensory, frontal, and subcortical regions. The deep location of the claustrum, with its fine structure, has limited the degree to which it could be studied in vivo. Particularly in humans, identifying the claustrum using magnetic resonance imaging (MRI) is extremely challenging, even manually. Therefore, automatic segmentation of the claustrum is an invaluable step toward enabling extensive and reproducible research of the anatomy and function of the human claustrum. In this study, we developed an automatic algorithm for segmenting the human dorsal claustrum in vivo using high-resolution MRI. Using this algorithm, we segmented the dorsal claustrum bilaterally in 1068 subjects of the Human Connectome Project Young Adult dataset, a publicly available high-resolution MRI dataset. We found good agreement between the automatic and manual segmentations performed by 2 observers in 10 subjects. We demonstrate the use of the segmentation in analyzing the covariation of the dorsal claustrum with other brain regions, in terms of macro- and microstructure. We identified several covariance networks associated with the dorsal claustrum. We provide an online repository of 1068 bilateral dorsal claustrum segmentations.


2020 ◽  
Vol 36 (3) ◽  
pp. 481-489
Author(s):  
Tianwen Han ◽  
Pathmaja Paramsothy ◽  
Jaekyoung Hong ◽  
Daniel Isquith ◽  
Dongxiang Xu ◽  
...  

Author(s):  
Gerard T. Luk-Pat ◽  
Garry E. Gold ◽  
Eric W. Olcott ◽  
Bob S. Hu ◽  
Dwight G. Nishimura

2012 ◽  
Vol 32 (3) ◽  
pp. 425-436 ◽  
Author(s):  
Manon Brundel ◽  
Jeroen de Bresser ◽  
Jeroen J van Dillen ◽  
L Jaap Kappelle ◽  
Geert Jan Biessels

Vascular cognitive impairment is an umbrella term for cognitive dysfunction associated with and presumed to be caused by vascular brain damage. Autopsy studies have identified microinfarcts as an important neuropathological correlate of vascular cognitive impairment that escapes detection by conventional magnetic resonance imaging (MRI). As a frame of reference for future high-resolution MRI studies, we systematically reviewed the literature on neuropathological studies on cerebral microinfarcts in the context of vascular disease, vascular risk factors, cognitive decline and dementia. We identified 32 original patient studies involving 10,515 people. The overall picture is that microinfarcts are common, particularly in patients with vascular dementia (weighted average 62%), Alzheimer's disease (43%), and demented patients with both Alzheimer-type and cerebrovascular pathology (33%) compared with nondemented older individuals (24%). In many patients, multiple microinfarcts were detected. Microinfarcts are described as minute foci with neuronal loss, gliosis, pallor, or more cystic lesions. They are found in all brain regions, possibly more so in the cerebral cortex, particularly in watershed areas. Reported sizes vary from 50 μm to a few mm, which is within the detection limit of current high-resolution MRI. Detection of these lesions in vivo would have a high potential for future pathophysiological studies in vascular cognitive impairment.


IRBM ◽  
2011 ◽  
Vol 32 (3) ◽  
pp. 204-213 ◽  
Author(s):  
T.T. Dao ◽  
P. Pouletaut ◽  
J.-C. Goebel ◽  
A. Pinzano ◽  
P. Gillet ◽  
...  

Neurosurgery ◽  
2003 ◽  
Vol 52 (6) ◽  
pp. NA
Author(s):  
JAMES S. WALDRON ◽  
ANDREW T. PARSA

2006 ◽  
Vol 39 (14) ◽  
pp. 2611-2622 ◽  
Author(s):  
Zhi-Yong Li ◽  
Simon Howarth ◽  
Rikin A. Trivedi ◽  
Jean M. U-King-Im ◽  
Martin J. Graves ◽  
...  

NeuroImage ◽  
2015 ◽  
Vol 115 ◽  
pp. 117-137 ◽  
Author(s):  
Juan Eugenio Iglesias ◽  
Jean C. Augustinack ◽  
Khoa Nguyen ◽  
Christopher M. Player ◽  
Allison Player ◽  
...  

Stroke ◽  
2007 ◽  
Vol 38 (6) ◽  
pp. 1812-1819 ◽  
Author(s):  
Emmanuel Touzé ◽  
Jean-François Toussaint ◽  
Joël Coste ◽  
Emmanuelle Schmitt ◽  
Fabrice Bonneville ◽  
...  

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