Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat

2011 ◽  
Vol 78 (2) ◽  
pp. 124-138 ◽  
Author(s):  
Patrick Turmel ◽  
Julie Dufresne ◽  
Louis Hermo ◽  
Charles E. Smith ◽  
Silvia Penuela ◽  
...  
1985 ◽  
Vol 248 (3) ◽  
pp. E274-E280 ◽  
Author(s):  
T. T. Turner ◽  
L. L. Ewing ◽  
C. E. Jones ◽  
S. S. Howards ◽  
B. Zegeye

The control of androgen concentrations in the intraluminal fluids of the male reproductive tract is not well understood. The present experiments were performed to determine the effects of hypophysectomy, hypophysectomy plus testosterone (T), and hypophysectomy plus pregnenolone treatment on intraluminal androgen concentrations in the adult rat testis and epididymis. T and 5 alpha-dihydrotestosterone (DHT) concentrations were determined in the vascular, interstitial, and intraluminal compartments of the epididymis. Testicular and epididymal morphology also were examined under light microscopy. Hypophysectomy of at least 5 days duration significantly reduced T and DHT concentrations in serum, tissues, and intraluminal fluids of the reproductive tract. T replacement for 14 days, which produced peripheral T concentrations of 5 ng/ml, did not support intraluminal androgen concentrations in the seminiferous tubules equivalent to controls; rete testis androgen concentrations were similar to controls, however. Pregnenolone administration at 2 mg X rat-1 X day-1 for 14 days did not maintain spermatogenesis nor intraluminal T concentrations in the seminiferous tubules equivalent to controls; however, a low level of spermatogenesis continued when intraluminal and tissue androgen concentrations were maintained at 10-20% of controls by either the testosterone and pregnenolone treatments.


2011 ◽  
Vol 85 (Suppl_1) ◽  
pp. 555-555
Author(s):  
Erick J.R. Silva ◽  
Luciana Honda ◽  
Sheilla A. Ferreira ◽  
Marilia T. Patrao ◽  
James K. Tsuruta ◽  
...  

Aquaculture ◽  
1989 ◽  
Vol 78 (3-4) ◽  
pp. 365-377 ◽  
Author(s):  
P. Talbot ◽  
D. Howard ◽  
J. Leung-Trujillo ◽  
T.W. Lee ◽  
W-Y. Li ◽  
...  

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