Basigin expression and regulation in mouse ovary during the sexual maturation and development of corpus luteum

2004 ◽  
Vol 68 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Hong Chang ◽  
Hua Ni ◽  
Xing-Hong Ma ◽  
Li-Bin Xu ◽  
Kenji Kadomatsu ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Sexual Maturation ◽  
Mouse Ovary

scholarly journals Differential expression and regulation of prostaglandin E synthases in the mouse ovary during sexual maturation and luteal development

2006 ◽  
Vol 189 (1) ◽  
pp. 89-101 ◽  
Author(s):  
Tong Sun ◽  
Wen-Bo Deng ◽  
Hong-Lu Diao ◽  
Hua Ni ◽  
Yu-Yan Bai ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Chorionic Gonadotropin ◽  
Granulosa Cells ◽  
Sexual Maturation ◽  
Mrna Level ◽  
Follicular Development ◽  
Prostaglandin E ◽  
Female Reproduction ◽  
Mouse Ovary ◽  
Equine Chorionic Gonadotropin

Prostaglandin (PGE) 2 is the most common prostanoid and plays an important role in female reproduction. The aim of this study was to examine the expression and regulation of microsomal (m) PGE synthase (PGES)-1 and cytosolic (c) PGES in the mouse ovary during sexual maturation, gonadotropin treatment and luteal development by in situ hybridization and immunohistochemistry. Both mPGES-1 mRNA signals and immunostaining were localized in the granulosa cells, but not in the thecal cells and oocytes. cPGES mRNA signals were localized in both granulosa cells and oocytes, whereas cPGES immunostaining was exclusively localized in the oocytes. In our superovulated model of immature mice, there was a basal level of mPGES-1 mRNA signals in the granulosa cells at 48 h after equine chorionic gonadotropin (eCG) treatment. mPGES-1 mRNA level was induced by human chorionic gonadotropin (hCG) treatment for 0.5 h, whereas mPGES-1 immunostaining was slightly induced at 0.5 h after hCG treatment and reached a maximal level at 3 h after hCG treatment. eCG treatment had no obvious effects on either cPGES mRNA signals or immunostaining. A strong level of cPGES immunostaining was present in both unstimulated and eCG-treated groups. Both mPGES-1 mRNA signals and immunostaining were highly detected in the corpus luteum 2 days post-hCG injection and declined from days 3 to 7 post-hCG injection. cPGES immunostaining was at a basal level or not detectable from days 1 to 7 after hCG injection and was highly expressed in the corpus luteum from days 9 to 15 post-hCG injection. PGE2 biosynthesized through the mPGES-1 pathway may be important for follicular development, ovulation and luteal formation.

Hormonal regulation of prostaglandin F2 alpha receptor gene expression in mouse ovary

1996 ◽  
Vol 271 (4) ◽  
pp. E686-E693
Author(s):  
J. Sugatani ◽  
Y. Masu ◽  
M. Nishizawa ◽  
K. Sakamoto ◽  
T. Houtani ◽  
...  
Keyword(s):  
Gene Expression ◽  
Corpus Luteum ◽  
Hormonal Regulation ◽  
Receptor Gene ◽  
Mrna Level ◽  
Dependent Manner ◽  
Mouse Ovary ◽  
Receptor Mrna ◽  
Prostaglandin F2 Alpha ◽  
Receptor Gene Expression

In this study we examined regulation by pituitary gonadotropins of the prostaglandin F2 alpha (PGF2 alpha) receptor gene expression in the mouse ovary. Administration of pregnant mare serum gonadotropin (PMSG) to 35-day-old mice in the diestrus phase stimulated the ovary and enhanced the production of progesterone at 1 h PMSG also increased the ovarian PGF2 alpha receptor mRNA level in a time-dependent manner, reaching a sixfold maximum at 1 h. These actions of PMSG were mimicked by human chorionic gonadotropin (hCG), follicle-stimulating hormone (FSH), and cholera toxin, all of which elevate intracellular adenosine 3',5'-cyclic monophosphate (cAMP). In situ hybridization revealed that PGF2 alpha receptor mRNA was localized to the corpus luteum, but the intensity of staining varied among corpora lutea in the same ovary. Exogenous PGF2 alpha inhibited the PMSG-stimulated progesterone production. These results demonstrate that gonadotropins may induce the expression of the PGF2 alpha receptor gene in luteal cells of the corpus luteum, probably by acting through a cAMP-mediated pathway, and that expression of the PGF2 alpha receptor may be functionally associated with the decrease in serum progesterone level.

scholarly journals The corpora lutea of the mouse, with special reference to fat accumulation during the œstrous cycle

1930 ◽  
Vol 106 (747) ◽  
pp. 578-595 ◽  
Keyword(s):  
Special Reference ◽  
Corpus Luteum ◽  
Experimental Work ◽  
Laboratory Animals ◽  
Corpora Lutea ◽  
Mouse Ovary ◽  
Short Account ◽  
Cellular Degeneration ◽  
Pregnancy And Lactation ◽  
Considerable Period

Although the histological literature on the corpus luteum is very extensive, a description of cellular and fat changes in the organ, which distinguishes between the corpora lutea of ovulabion, pseudo-pregnancy, pregnancy, and lactation where these are differentiated, is still lacking for some laboratory animals. In view of experimental work now in progress, it was thought that a short account of the mouse corpus luteum on these lines might be of value. In the absence of pregnancy, old corpora lutea persist for a considerable period in the mouse ovary, and after the initial signs of cellular degeneration, which are not always very obvious, further changes are slow to occur. With suitable histological methods, however, it is possible to distinguish, even after they are fully developed, the corpora lutea belonging to the last one and sometimes two or more oestrous periods.

Differential Expression and Regulation of Angiopoietin-2 in the Mouse Ovary During Sexual Maturation and Luteal Development.

2011 ◽  
Vol 85 (Suppl_1) ◽  
pp. 693-693 ◽  
Author(s):  
Bin Guo ◽  
Wei Wang ◽  
Lu Zhang ◽  
Xue-Chao Tian ◽  
Shou-Tang Wang ◽  
...  
Keyword(s):  
Differential Expression ◽  
Sexual Maturation ◽  
Mouse Ovary ◽  
Angiopoietin 2

Inductive influence of testosterone upon central sexual maturation in the rat

Development ◽  
1967 ◽  
Vol 17 (1) ◽  
pp. 171-175
Author(s):  
W. N. Adams Smith ◽  
M. T. Peng
Keyword(s):  
Corpus Luteum ◽  
Sex Hormones ◽  
Adult Male ◽  
Sexual Maturation ◽  
Male Genitalia ◽  
Testosterone Propionate ◽  
Single Injection ◽  
Male Rats ◽  
Corpora Lutea

The influence of the testis and of testosterone upon the development of the male genitalia has been extensively investigated and a number of reviews of this work have been published (Jost, 1960; Burns, 1961). However, Witschi (1957) has stressed the need to distinguish between adult sex hormones, such as testosterone, and the secretions of the immature gonad. The formation of corpora lutea in the ovaries transplanted to adult male rats which had been castrated at birth, and the absence of corpus luteum formation in ovaries transplanted to male hosts bearing transplanted testes in the neck from birth, was reported by Pfeiffer in 1936. Similar observations have been reported by Yazaki (1960) and Harris (1964). A single injection of testosterone propionate has been found to lead to permanent sterility and a loss of corpus luteum formation in the ovaries of mice (Barraclough & Leathern, 1954) and rats (Barraclough, 1961).

Changes in the Distribution of Tenascin and Fibronectin in the Mouse Ovary During Folliculogenesis, Atresia, Corpus Luteum Formation and Luteolysis

2005 ◽  
Vol 22 (2) ◽  
pp. 237-245 ◽  
Author(s):  
Keiko Yasuda ◽  
Emi Hagiwara ◽  
Akiko Takeuchi ◽  
Chinatsu Mukai ◽  
Chiyuki Matsui ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Mouse Ovary
Sign in / Sign up

Export Citation Format

Share Document