Heat labile activating substance for ornithine decarboxylase activity in sea urchin eggs

1978 ◽  
Vol 1 (2) ◽  
pp. 129-136 ◽  
Author(s):  
Shinichiro Kusunoki ◽  
Ikuo Yasumasu
Keyword(s):  
Ornithine Decarboxylase ◽  
Sea Urchin ◽  
Decarboxylase Activity ◽  
Sea Urchin Eggs ◽  
Ornithine Decarboxylase Activity ◽  
Heat Labile

scholarly journals Early cyclical changes in polyamine synthesis during sea-urchin development

Development ◽  
1973 ◽  
Vol 30 (1) ◽  
pp. 243-256
Author(s):  
Carol-Ann Manen ◽  
Diane H. Russell
Keyword(s):  
Ornithine Decarboxylase ◽  
Sea Urchin ◽  
Sea Urchins ◽  
Strongylocentrotus Purpuratus ◽  
Decarboxylase Activity ◽  
Early Cleavage ◽  
Polyamine Synthesis ◽  
Selective Degradation ◽  
Ornithine Decarboxylase Activity ◽  
Cleavage Stages

The polyamines, putrescine, spermidine, and spermine, undergo dramatic cyclical variation in both synthesis and accumulation during the early cleavage stages of sea-urchin development. Ornithine decarboxylase activity (putrescine synthesis) in developing Strongylocentrotus purpuratus exhibits maxima at ½ and 2 h after fertilization; increases in ornithine decarboxylase activity appear to correspond to the first and second S phases. Putrescine-stimulated S-adenosyl-l-methionine decarboxylase (spermidine synthesis) and spermidine-stimulated S-adenosyl-l-methionine decarboxylase (spermine synthesis) activities reflect rises during prophase-metaphase of the first and second divisions in two species of sea urchins. Cyclical changes in the concentrations of these three amines were evident also. In general, there were drops in the levels of the amines prior to cleavage. These rapid declines in polyamine concentrations may reflect (1) selective degradation or (2) selective secretion.

Ornithine Decarboxylase Activity in Cultured Endothelial Cells Stimulated by Serum, Thrombin and Serotonin

1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro
Keyword(s):  
Endothelial Cells ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Aortic Endothelial Cells ◽  
Ornithine Decarboxylase Activity ◽  
Rate Limiting Step ◽  
Bovine Aortic Endothelial Cells ◽  
Limiting Step ◽  
Rate Limiting ◽  
Serum Serotonin

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.

scholarly journals ORNITHINE DECARBOXYLASE ACTIVITY AS A PROGNOSTIC MARKER FOR COLORECTAL CANCER

2007 ◽  
Vol 53 (1) ◽  
pp. 1-9 ◽  
Author(s):  
YUTAKA HOSHINO ◽  
SHINYA TERASHIMA ◽  
YASUSHI TERANISHI ◽  
MASANORI TERASHIMA ◽  
MICHIHIKO KOGURE ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Marker ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Ornithine Decarboxylase Activity
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