Erythrocyte fatty acid profiles in childhood malignancy

1990 ◽  
Vol 18 (3) ◽  
pp. 207-208 ◽  
Author(s):  
W. Heard ◽  
A. Kohler ◽  
A. D. Postle
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Profiles ◽  
Childhood Malignancy ◽  
Erythrocyte Fatty Acid

scholarly journals n-3 PUFAs improve erythrocyte fatty acid profile in patients with small AAA: a randomized controlled trial

2019 ◽  
Vol 60 (6) ◽  
pp. 1154-1163 ◽  
Author(s):  
Lara T. Meital ◽  
Mark T. Windsor ◽  
Rebecca M. L. Ramirez Jewell ◽  
Peter Young ◽  
Karl Schulze ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Acid Content ◽  
Desaturase Activity ◽  
Fatty Acid Content ◽  
Fatty Acid Profiles ◽  
Omega 3 ◽  
Distribution Width ◽  
Pufa Supplementation ◽  
Adrenic Acid ◽  
Erythrocyte Fatty Acid

Abdominal aortic aneurysm (AAA) is an important cause of death in older adults, which has no current drug therapy. Inflammation and abnormal redox status are believed to be key pathogenic mechanisms for AAA. In light of evidence correlating inflammation with aberrant fatty acid profiles, this study compared erythrocyte fatty acid content in 43 AAA patients (diameter 3.0–4.5 cm) and 52 healthy controls. In addition, the effect of omega-3 PUFA (n-3 PUFA) supplementation on erythrocyte fatty acid content was examined in a cohort of 30 AAA patients as part of a 12 week randomized placebo-controlled clinical trial. Blood analyses identified associations between AAA and decreased linoleic acid (LA), and AAA and increased Δ6-desaturase activity and biosynthesis of arachidonic acid (AA) from LA. Omega-3 PUFA supplementation (1.5 g DHA + 0.3 g EPA/day) decreased red blood cell distribution width (14.8 ± 0.4% to 13.8 ± 0.2%; P = 0.003) and levels of pro-inflammatory n-6 PUFAs (AA, 12.46 ± 0.23% to 10.14 ± 0.3%, P < 0.001; adrenic acid, 2.12 ± 0.13% to 1.23 ± 0.09%; P < 0.001). In addition, Δ-4 desaturase activity increased (DHA/docosapentaenoic acid ratio, 1.85 ± 0.14 to 3.93 ± 0.17; P < 0.001) and elongase 2/5 activity decreased (adrenic acid/AA ratio, 0.17 ± 0.01 to 0.12 ± 0.01; P < 0.01) following supplementation. The findings suggest that n-3 PUFAs improve fatty acid profiles and ameliorate factors associated with inflammation in AAA patients.

scholarly journals Association between Maternal and Foetal Erythrocyte Fatty Acid Profiles and Birth Weight

Nutrients ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 402 ◽  
Author(s):  
Giulia Cinelli ◽  
Marta Fabrizi ◽  
Lucilla Ravà ◽  
Fabrizio Signore ◽  
Pamela Vernocchi ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Birth Weight ◽  
Fatty Acid Profiles ◽  
Erythrocyte Fatty Acid

Erythrocyte Fatty Acid Profiles in Patients with Bronchogenic Carcinoma

1987 ◽  
Vol 24 (6) ◽  
pp. 604-607 ◽  
Author(s):  
A Taylor ◽  
A Manche ◽  
I Wilson ◽  
D Watson ◽  
H Pandov ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Surgical Resection ◽  
Bronchogenic Carcinoma ◽  
Healthy Adults ◽  
Fatty Acid Profiles ◽  
Diagnosis And Prognosis ◽  
Acid Ratio ◽  
Significant Difference ◽  
Erythrocyte Fatty Acid

The use of the erythrocyte stearic:oleic acid ratio in the diagnosis and prognosis of bronchogenic carcinoma has been assessed. Although there was a significant difference ( P<0·02) in the erythrocyte stearic:oleic acid ratio between bronchogenic carcinoma patients and healthy adults, the large overlap observed in the two groups rendered the test unsuitable for the diagnosis of malignancy. Furthermore, there was no consistent rise in this ratio after surgical resection, indicating the test to be of little prognostic use. A new explanation for the lower stearic:oleic acid ratios in certain patients has been postulated.

Trophic niches determined from fatty acid profiles of sympatric coral reef mesopredators

2019 ◽  
Vol 632 ◽  
pp. 159-174 ◽  
Author(s):  
SL Bierwagen ◽  
H Pethybridge ◽  
MR Heupel ◽  
A Chin ◽  
CA Simpfendorfer
Keyword(s):  
Fatty Acid ◽  
Coral Reef ◽  
Fatty Acid Profiles ◽  
Trophic Niches

The assessment of biofilm community composition on plumbing materials in filtered and unfiltered water distribution systems

2003 ◽  
Vol 3 (1-2) ◽  
pp. 187-191
Author(s):  
M.M. Critchley ◽  
N.J. Cromar ◽  
H.J. Fallowfield
Keyword(s):  
Drinking Water ◽  
Fatty Acid ◽  
Community Composition ◽  
Distribution Systems ◽  
Water Distribution ◽  
Water Distribution Systems ◽  
Polymer Materials ◽  
Fatty Acid Profiles ◽  
Water Supplies ◽  
Drinking Water Distribution Systems

Biofilms have been extensively characterised within drinking water distribution systems. However, the significance of materials on biofilm species diversity is not established. This study investigated the community composition of biofilms on plumbing materials receiving filtered and unfiltered water supplies. Biofilms were extracted from polybutylene, polyethylene, cross-linked polyethylene, unplasticised polyvinyl chloride and copper tubes in sampling rigs receiving Murray-Onkaparinga water before or after filtration. Biofilms were extracted and analysed for fatty acid composition using the FAME™ methodology. There were differences in the fatty acid profiles of biofilms and the respective water supplies, indicating differences in the attached and planktonic communities. The results also showed significant differences in the fatty acid profiles of biofilms on the polymer materials compared to copper, suggesting variations in biofilm populations on the different materials. The potential for materials to select for microbial populations has significant implications for the ecology of drinking water biofilms.

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