Appendiceal carcinoid tumors in children: Does size matter?

2001 ◽  
Vol 38 (1) ◽  
pp. 65-66 ◽  
Author(s):  
Maziar Assadi ◽  
Rainer Kubiak ◽  
Georges Kaiser
Keyword(s):  
Carcinoid Tumors ◽  
Appendiceal Carcinoid ◽  
Size Matter

Practice Patterns and Guideline Non-Adherence in Surgical Management of Appendiceal Carcinoid Tumors

2018 ◽  
Vol 227 (4) ◽  
pp. e218
Author(s):  
Danielle R. Heller ◽  
Raymond A. Jean ◽  
Vadim Kurbatov ◽  
Alexander S. Chiu ◽  
Sajid A. Khan
Keyword(s):  
Surgical Management ◽  
Practice Patterns ◽  
Carcinoid Tumors ◽  
Appendiceal Carcinoid

scholarly journals NEW CLASSIFICATION AND DIAGNOSIS OF APPENDICEAL CARCINOID TUMORS

2012 ◽  
pp. 24-30 ◽  
Author(s):  
Vuka Katić ◽  
Boris Đinđić ◽  
Marijola Mojsilović ◽  
Pavle Mladenović ◽  
Vladmila Bojanić ◽  
...  
Keyword(s):  
Carcinoid Tumors ◽  
New Classification ◽  
Appendiceal Carcinoid

Management of appendiceal carcinoid tumors in children

2015 ◽  
Vol 198 (2) ◽  
pp. 384-387 ◽  
Author(s):  
Sara C. Fallon ◽  
M. John Hicks ◽  
Jennifer L. Carpenter ◽  
Sanjeev A. Vasudevan ◽  
Jed G. Nuchtern ◽  
...  
Keyword(s):  
Carcinoid Tumors ◽  
Appendiceal Carcinoid

Prognostic significance of lymph node sampling in node-negative appendiceal carcinoids.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 678-678
Author(s):  
Mustafa Raoof ◽  
Sinziana Dumitra ◽  
Gagandeep Singh ◽  
Yuman Fong ◽  
Byrne Lee
Keyword(s):  
Overall Survival ◽  
Lymph Node ◽  
Locally Advanced ◽  
Prognostic Significance ◽  
Cox Proportional Hazards Model ◽  
Carcinoid Tumors ◽  
Primary Therapy ◽  
Tumor Spread ◽  
Node Negative ◽  
Appendiceal Carcinoid

678 Background: Surgical resection is the primary therapy for local and locally advanced carcinoid tumors of the appendix. The extent of surgery is largely dictated by the size of the tumor. Tumors >2 cm require a right hemicolectomy with associated mesenteric lymphadenectomy. What constitutes an adequate mesenteric lymphadenectomy is not known. Methods: This is a study of a contemporary cohort from NCI’s SEER database (Jan, 2004- Nov, 2012). Patients with non-metastatic appendiceal carcinoid tumors were included. Surgical extent was defined as limited (appendectomy or illeocecectomy) or extended (hemicolectomy). Primary outcome was overall survival (OS). Survival analysis was performed using the Kaplan-Meier and Cox-proportional hazards model. Results: Of the total 1,104 patients that met the inclusion criteria, 52% were female, 88% were white and majority were middle aged (40-60y) 45%. Majority of the tumors were <2 cm (49.3%) and lymph node(LN) negative 85%. Median LN retrieved were 10 (IQR 0-17). Median follow-up was 32 months (IQR 10-61). A multivariate Cox-proportional hazard model demonstrated that increasing age, tumor size > 3cm, tumor spread to contiguous organs, LN positivity and LN count <11 (HR 1.78: 95%CI 1.17-2.69; p=0.006) are associated with worse OS. Five-year overall survival increased with the number of LN retrieved (LN 1-10, 81.4%; LN >10, 85.9%, p=0.035). Stratified analysis by LN status demonstrated that LN count <11 was an independent predictor of worse OS in node negative patients (HR 2.10: 95%CI 1.25-3.53; p=0.005) but not node positive patients (p=0.65). Subset analysis by tumors size demonstrated that prognostic value of LN count <11 was only significant for tumors greater than 3 cm (HR 2.32: 95%CI 1.15-2.03; p=0.018). Conclusions: This is the largest study to date that looks at prognostic significance of LN count for appendiceal carcinoids. The number of LNs evaluated is an independent prognostic factor in pathologic node-negative, appendiceal carcinoid tumors measuring greater than 3 cm. This data supports performing a formal lymphadenectomy (>10 LN) even if no mesenteric disease is visible for adequate staging.

Appendiceal Carcinoid Tumors: Is There a Survival Advantage to Colectomy over Appendectomy?

2019 ◽  
Vol 24 (5) ◽  
pp. 1149-1157
Author(s):  
Carlos Guzman ◽  
Sowmya Boddhula ◽  
Narmadha Panneerselvam ◽  
Chetan Dodhia ◽  
Nicholas J Hellenthal ◽  
...  
Keyword(s):  
Carcinoid Tumors ◽  
Survival Advantage ◽  
Appendiceal Carcinoid

Carcinoid Tumors of the Appendix: Are These Tumors Identifiable Prospectively on Preoperative CT?

2010 ◽  
Vol 76 (3) ◽  
pp. 273-275 ◽  
Author(s):  
Courtney A. Coursey ◽  
Rendon C. Nelson ◽  
Ricardo D. Moreno ◽  
Leslie G. Dodd ◽  
Mayur B. Patel ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Tumor Size ◽  
Ct Images ◽  
Database Search ◽  
Carcinoid Tumors ◽  
Current Procedural Terminology ◽  
Appendiceal Carcinoid ◽  
Preoperative Ct ◽  
Distal Location ◽  
Pathology Reports

The purpose of this study was to determine if carcinoid tumors of the appendix were identified prospectively on preoperative CT at our institution during the last decade. A surgical database search performed using the Current Procedural Terminology codes for appendectomy and colectomy yielded 2108 patients who underwent appendectomy or colectomy with removal of the appendix from January 1998 through September 2007. Pathology reports were reviewed to identify patients in whom an appendiceal carcinoid tumor was identified. Preoperative CT reports and images were reviewed. Twenty-three carcinoid tumors (1.1%; 15 women [65.2%], eight men [34.8%]; average age 54 years [range, 23 to 86 years]) were identified. Ten patients underwent preoperative CT. No tumors were identified prospectively on CT. Images were available for rereview for eight patients. Studies were acquired with 16- (n = 7) and four- (n = 1) slice CT scanners. Average reported tumor size was 6.1 mm (range, 1.5 to 15 mm; n = 18). A tip or distal location was reported for all tumors for which a location was given (n = 15). Carcinoid tumors occurred in 1.1 per cent of appendix specimens. These tumors were all less than or 1.5 cm in size. Likely as a result of their small size, none of these tumors was identified prospectively on preoperative CT.

Appendiceal carcinoid tumors: Predictors of lymph node metastasis and the impact of right hemicolectomy on survival

2010 ◽  
Vol 103 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Shawn S. Groth ◽  
Beth A. Virnig ◽  
Waddah B. Al-Refaie ◽  
Stephanie L. Jarosek ◽  
Eric H. Jensen ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Right Hemicolectomy ◽  
Carcinoid Tumors ◽  
Appendiceal Carcinoid ◽  
Node Metastasis ◽  
The Impact

Systematic review and meta-analysis of appendiceal carcinoid tumors in children

2018 ◽  
Vol 65 (8) ◽  
pp. e27069 ◽  
Author(s):  
Ike Njere ◽  
Lisa Linnéa Smith ◽  
Dushanthi Thurairasa ◽  
Rubina Malik ◽  
Iona Jeffrey ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Carcinoid Tumors ◽  
Appendiceal Carcinoid
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