Appendiceal carcinoid tumors: Predictors of lymph node metastasis and the impact of right hemicolectomy on survival

2010 ◽  
Vol 103 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Shawn S. Groth ◽  
Beth A. Virnig ◽  
Waddah B. Al-Refaie ◽  
Stephanie L. Jarosek ◽  
Eric H. Jensen ◽  
...  
Author(s):  
Subbiah Shanmugam ◽  
Gopu Govindasamy ◽  
X. Gerald Anand Raja

<p class="abstract"><strong>Background:</strong> Depth of invasion is included in the staging of oral cavity malignancies in the recent 8<sup>th</sup> edition of American Joint Committee on Cancer or tumour, node and metastasis staging system. This study analyses the impact of diffuse optical imaging (DOI) on incidence of lymph node involvement, stage migration, postoperative margin and independency.</p><p class="abstract"><strong>Methods:</strong> Postoperative HPE of fifty patients with oral cavity malignancy operated in our institute from January 2018 were collected. Depth of invasion and other pathological parameters were documented. DOI divided into three groups and statistical analysis done.  </p><p class="abstract"><strong>Results:</strong> No lymph node metastasis is found in superficial tumours, 43% of intermediate thickness and 76% of deep tumours had lymph node involvement. Positive margin is seen only in patients with tumour DOI more than 0.5 cm, more than 50% of deep tumours had close margins while 75% of superficial tumours had adequate margin. Out of the 24 T3 tumours in this study 13 were upstaged due to inclusion of DOI, which would have been T2 according to the previous staging system. There is 54.1% (13 out of 24) upstaging in T3 tumours (T2 to T3), 23% (3 out of 13) in T2 (T1 to T2). There is no significant correlation between DOI and anatomical site, tumour size, tumour thickness, lymphovascular invasion and grade.</p><p class="abstract"><strong>Conclusions:</strong> Depth of invasion in oral cavity malignancies impacts adversely lymph node metastasis and margin status. It is an independent prognostic factor in oral cavity malignancy.</p>


2010 ◽  
Vol 45 (11) ◽  
pp. e1-e5 ◽  
Author(s):  
Grigore Cernaianu ◽  
Andrea Tannapfel ◽  
Joseph Nounla ◽  
Roberto Gonzalez-Vasquez ◽  
Thomas Wiesel ◽  
...  

2021 ◽  
Vol 32 (2) ◽  
pp. 302-303
Author(s):  
Daryl Ramai ◽  
Jameel Singh ◽  
Mohamed Barakat ◽  
Saurabh Chandan ◽  
Douglas G. Adler

2011 ◽  
Vol 285 (4) ◽  
pp. 1119-1124 ◽  
Author(s):  
Taner Turan ◽  
Deniz Hızlı ◽  
Saynur Sarici Yılmaz ◽  
Burcu Gundogdu ◽  
Nurettin Boran ◽  
...  

2019 ◽  
Vol 08 (01) ◽  
pp. 44-46 ◽  
Author(s):  
Nizara Baishya ◽  
Tashnin Rahman ◽  
Ashok Kumar Das ◽  
Chandi Ram Kalita ◽  
Jagannath Dev Sharma ◽  
...  

Abstract Objective: The main objective of this study was to analyze the clinical behavior and the impact of nodal metastasis on the prognosis of upper alveolus squamous cell carcinoma (SCC). Materials and Methods: The medical records of 110 patients with SCC of the upper alveolus (International Classification of Diseases-10-C03.0) diagnosed during 2010–2015 were reviewed. Survival analysis was done using the Kaplan–Meier method and was compared using log rank-test. P < 0.05 was considered statistically significant. Results: Of the 110 patients, 59 were males and 51 were females. Forty-six (41.8%) patients presented with lymph node metastasis. Fifty-three (51.8%) patients presented in Stage IVA, thirty (27.3%) patients in Stage IVB, ten (9.1%) patients in Stage III, 12 (10.9%) patients in Stage II. The 5-year overall survival (OS) was 71.1% in Stage II, in Stage III it was 65.6%, in Stage it was IVA 56.7%, and in Stage IVB it was 19.4% (P = 0.02). The 5-year OS for node negative compared with node positive was 66.3% versus 37.3%, respectively (P = 0.019). Conclusion: Presence of lymph node metastasis is associated with lower survival rates. Adequate surgical resection with adjuvant treatment, where necessary, offers the best chance of disease control.


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