Genetic factors determining cutaneous basal cell carcinoma phenotype

2001 ◽  
Vol 36 (5) ◽  
pp. 559-563 ◽  
Author(s):  
Sudarshan Ramachandran ◽  
Anthony A. Fryer ◽  
Richard C. Strange
2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Sitong Ju ◽  
Wanlin Fan ◽  
Alexander C. Rokohl ◽  
Yongwei Guo ◽  
Vinodh Kakkassery ◽  
...  

2011 ◽  
Vol 63 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Cosmeri Rizzato ◽  
Dominique Scherer ◽  
Peter Rudnai ◽  
Eugen Gurzau ◽  
Kvetoslava Koppova ◽  
...  

2020 ◽  
Vol 21 (15) ◽  
pp. 5572 ◽  
Author(s):  
Emi Dika ◽  
Federica Scarfì ◽  
Manuela Ferracin ◽  
Elisabetta Broseghini ◽  
Emanuela Marcelli ◽  
...  

Basal cell carcinoma (BCC) is the most common type of carcinoma worldwide. BCC development is the result of a complex interaction between environmental, phenotypic and genetic factors. However, despite the progress in the field, BCC biology and mechanisms of resistance against systemic treatments have been poorly investigated. The aim of the present review is to provide a revision of BCC histological and molecular features, including microRNA (miRNA) dysregulation, with a specific focus on the molecular basis of BCC systemic therapies. Papers from the last ten years regarding BCC genetic and phenotypic alterations, as well as the mechanism of resistance against hedgehog pathway inhibitors vismodegib and sonidegib were included. The involvement of miRNAs in BCC resistance to systemic therapies is emerging as a new field of knowledge.


Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.


2000 ◽  
Vol 39 (5) ◽  
pp. 397-398 ◽  
Author(s):  
Hyoung-Joo Kim ◽  
Youn-Soo Kim ◽  
Ki-Beom Suhr ◽  
Tae-Young Yoon ◽  
Jeung-Hoon Lee ◽  
...  

1978 ◽  
Vol 114 (12) ◽  
pp. 1845-1845 ◽  
Author(s):  
G. P. Lupton

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