Evaluation of motion mitigation using abdominal compression in the clinical implementation of pencil beam scanning proton therapy of liver tumors

2017 ◽  
Vol 44 (2) ◽  
pp. 703-712 ◽  
Author(s):  
Liyong Lin ◽  
Kevin Souris ◽  
Minglei Kang ◽  
Adam Glick ◽  
Haibo Lin ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Liver Tumors ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Abdominal Compression ◽  
Beam Scanning ◽  
Pencil Beam Scanning

SU-F-T-121: Abdominal Compression Effectively Reduces the Interplay Effect and Enables Pencil Beam Scanning Proton Therapy of Liver Tumors

2016 ◽  
Vol 43 (6Part14) ◽  
pp. 3489-3489
Author(s):  
K Souris ◽  
A Glick ◽  
M Kang ◽  
G Janssens ◽  
E Sterpin ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Liver Tumors ◽  
Pencil Beam ◽  
Abdominal Compression ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Interplay Effect

scholarly journals Clinical Implementation of Proton Therapy Using Pencil-Beam Scanning Delivery Combined With Static Apertures

2021 ◽  
Vol 11 ◽  
Author(s):  
Christian Bäumer ◽  
Sandija Plaude ◽  
Dalia Ahmad Khalil ◽  
Dirk Geismar ◽  
Paul-Heinz Kramer ◽  
...  
Keyword(s):  
At Risk ◽  
Proton Therapy ◽  
Target Volume ◽  
Delivery Mode ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Spot Scanning ◽  
The Mean

Proton therapy makes use of the favorable depth-dose distribution with its characteristic Bragg peak to spare normal tissue distal of the target volume. A steep dose gradient would be desired in lateral dimensions, too. The widespread spot scanning delivery technique is based, however, on pencil-beams with in-air spot full-widths-at-half-maximum of typically 1 cm or more. This hampers the sparing of organs-at-risk if small-scale structures adjacent to the target volume are concerned. The trimming of spot scanning fields with collimating apertures constitutes a simple measure to increase the transversal dose gradient. The current study describes the clinical implementation of brass apertures in conjunction with the pencil-beam scanning delivery mode at a horizontal, clinical treatment head based on commercial hardware and software components. Furthermore, clinical cases, which comprised craniopharyngiomas, re-irradiations and ocular tumors, were evaluated. The dosimetric benefits of 31 treatment plans using apertures were compared to the corresponding plans without aperture. Furthermore, an overview of the radiation protection aspects is given. Regarding the results, robust optimization considering range and setup uncertainties was combined with apertures. The treatment plan optimizations followed a single-field uniform dose or a restricted multi-field optimization approach. Robustness evaluation was expanded to account for possible deviations of the center of the pencil-beam delivery and the mechanical center of the aperture holder. Supplementary apertures improved the conformity index on average by 15.3%. The volume of the dose gradient surrounding the PTV (evaluated between 80 and 20% dose levels) was decreased on average by 17.6%. The mean dose of the hippocampi could be reduced on average by 2.9 GyRBE. In particular cases the apertures facilitated a sparing of an organ-at-risk, e.g. the eye lens or the brainstem. For six craniopharyngioma cases the inclusion of apertures led to a reduction of the mean dose of 1.5 GyRBE (13%) for the brain and 3.1 GyRBE (16%) for the hippocampi.

PO-1611: Clinical implementation of liver cancer treatments with pencil beam scanning proton therapy

2020 ◽  
Vol 152 ◽  
pp. S877
Author(s):  
F. Fracchiolla ◽  
F. Dionisi ◽  
R. Righetto ◽  
L. Widesott ◽  
I. Giacomelli ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Cancer Treatments ◽  
Beam Scanning ◽  
Pencil Beam Scanning

Clinical implementation of pencil beam scanning proton therapy for liver cancer with forced deep expiration breath hold

2021 ◽  
Vol 154 ◽  
pp. 137-144
Author(s):  
Francesco Fracchiolla ◽  
Francesco Dionisi ◽  
Roberto Righetto ◽  
Lamberto Widesott ◽  
Irene Giacomelli ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Proton Therapy ◽  
Breath Hold ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Beam Scanning ◽  
Pencil Beam Scanning

scholarly journals Validation and clinical implementation of an accurate Monte Carlo code for pencil beam scanning proton therapy

2018 ◽  
Vol 19 (5) ◽  
pp. 558-572 ◽  
Author(s):  
Sheng Huang ◽  
Minglei Kang ◽  
Kevin Souris ◽  
Christopher Ainsley ◽  
Timothy D. Solberg ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Monte Carlo Code ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Beam Scanning ◽  
Pencil Beam Scanning

scholarly journals Clinical Implementation of Preoperative Short-Course Pencil Beam Scanning Proton Therapy for Patients With Rectal Cancer

2020 ◽  
Vol 5 (5) ◽  
pp. 865-870
Author(s):  
Elizabeth B. Jeans ◽  
Krishan R. Jethwa ◽  
William S. Harmsen ◽  
Michelle Neben-Wittich ◽  
Jonathan B. Ashman ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Proton Therapy ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Short Course

scholarly journals Commissioning of a clinical pencil beam scanning proton therapy unit for ultra‐high dose rates (FLASH)

2021 ◽  
Author(s):  
Konrad P. Nesteruk ◽  
Michele Togno ◽  
Martin Grossmann ◽  
Anthony J. Lomax ◽  
Damien C. Weber ◽  
...  
Keyword(s):  
Proton Therapy ◽  
High Dose ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Dose Rates ◽  
Pencil Beam Scanning

scholarly journals Characterization of passive dosimeters in proton pencil beam scanning – A EURADOS intercomparison for mailed dosimetry audits in proton therapy centres

2021 ◽  
Vol 82 ◽  
pp. 134-143
Author(s):  
M. De Saint-Hubert ◽  
C. De Angelis ◽  
Ž. Knežević ◽  
B. Michalec ◽  
B. Reniers ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning
Sign in / Sign up

Export Citation Format

Share Document