scholarly journals Phenolic Metabolites in the Urine and Plasma of Healthy Men After Acute Intake of Purple Potato Extract Rich in Methoxysubstituted Monoacylated Anthocyanins

2021 ◽  
pp. 2000898
Author(s):  
Johanna Jokioja ◽  
Jasmine Percival ◽  
Mark Philo ◽  
Baoru Yang ◽  
Paul A. Kroon ◽  
...  
Keyword(s):  
Phenolic Metabolites ◽  
Healthy Men ◽  
Potato Extract ◽  
Acute Intake

scholarly journals Effects of aronia berry (poly)phenols on vascular function and gut microbiota: a double-blind randomized controlled trial in adult men

2019 ◽  
Vol 110 (2) ◽  
pp. 316-329 ◽  
Author(s):  
Geoffrey Istas ◽  
Eleanor Wood ◽  
Melanie Le Sayec ◽  
Claudia Rawlings ◽  
Jeeyoung Yoon ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Vascular Function ◽  
Cardiovascular Health ◽  
Controlled Trial ◽  
Healthy Population ◽  
Microbiota Composition ◽  
Double Blind ◽  
Phenolic Metabolites ◽  
Healthy Men ◽  
Gut Microbiota Composition

ABSTRACT Background Aronia melanocarpa is a rich source of (poly)phenols. Previous research has demonstrated that these berries may provide cardiovascular health benefits in high-risk populations. However, very few studies have investigated the effects of daily consumption of dietary achievable amounts of the berries in healthy subjects. Objectives The aim of this study was to investigate the effects of aronia berries on vascular function and gut microbiota composition in a healthy population. Methods A double-blind, placebo-controlled, parallel designed study was conducted in 66 healthy men randomly allocated to consume a (poly)phenol-rich extract (116 mg, 75 g berries), a whole fruit powder (12 mg, 10 g berries), or placebo (maltodextrin) for 12 wk. Flow-mediated dilation (FMD), arterial stiffness, blood pressure, heart rate, and serum biochemistry were assessed. Plasma (poly)phenol metabolites were analyzed by LC-MS. Gut microbiota composition was determined via 16S rRNA sequencing in stool samples. Results Consumption of aronia whole fruit and extract powder for 12 wk led to a significant increase in FMD over control of 0.9% ± 0.4% (95% CI: 0.13%, 1.72%) and 1.2% ± 0.4% (95% CI: 0.36%, 1.97%), respectively. Acute improvements in FMD were also observed 2 h after consumption of aronia extract on day 1 (1.1% ± 0.3%, P = 0.003) and 12 wk later (1.5% ± 0.4%, P = 0.0001). Circulating plasma phenolic metabolites increased upon consumption of the aronia treatments. Although no changes were found in gut microbiota diversity, consumption of aronia extract increased the growth of Anaerostipes (+10.6%, P = 0.01), whereas aronia whole fruit showed significant increases in Bacteroides (+193%, P = 0.01). Correlation analysis identified significant associations between changes in FMD, aronia-derived phenolic metabolites, and specific gut microbial genera. Conclusions In healthy men, consumption of aronia berry (poly)phenols improved endothelial function and modulated gut microbiota composition, indicating that regular aronia consumption has the potential to maintain cardiovascular health in individuals at low risk of cardiovascular disease. This trial was registered at CLINICALTRIALs.gov as NCT03041961.

Acute intake of moderate amounts of red wine or alcohol has no effect on the immune system of healthy men

2002 ◽  
Vol 41 (6) ◽  
pp. 264-270 ◽  
Author(s):  
Bernhard Watzl ◽  
Achim Bub ◽  
Karlis Briviba ◽  
Gerhard Rechkemmer
Keyword(s):  
Immune System ◽  
Red Wine ◽  
Healthy Men ◽  
Acute Intake

scholarly journals An Oral Lipid Challenge and Acute Intake of Caffeinated Coffee Additively Decrease Glucose Tolerance in Healthy Men

2011 ◽  
Vol 141 (4) ◽  
pp. 574-581 ◽  
Author(s):  
Marie-Soleil Beaudoin ◽  
Lindsay E. Robinson ◽  
Terry E. Graham
Keyword(s):  
Glucose Tolerance ◽  
Healthy Men ◽  
Caffeinated Coffee ◽  
Acute Intake

scholarly journals Validation of Dried Blood Spot Cards to Determine Apple Phenolic Metabolites in Human Blood and Plasma After an Acute Intake of Red-Fleshed Apple Snack

2018 ◽  
Vol 62 (23) ◽  
pp. 1800623 ◽  
Author(s):  
Silvia Yuste ◽  
Alba Macià ◽  
Iziar A. Ludwig ◽  
María-Paz Romero ◽  
Sara Fernández-Castillejo ◽  
...  
Keyword(s):  
Human Blood ◽  
Dried Blood Spot ◽  
Phenolic Metabolites ◽  
Acute Intake ◽  
Blood Spot

CFTR protein expression in healthy men spermatozoa is not correlated with fertilization rate of ova

2010 ◽  
Vol 34 (8) ◽  
pp. S12-S12
Author(s):  
Hong‑Ge Li ◽  
Chen Min Xu ◽  
Kun Li ◽  
Ya Ni ◽  
Wen‑Ying Chen ◽  
...  
Keyword(s):  
Protein Expression ◽  
Fertilization Rate ◽  
Healthy Men ◽  
Cftr Protein

Gene May Predict Aggression in Healthy Men

2006 ◽  
Vol 34 (10) ◽  
pp. 54
Author(s):  
PATRICE WENDLING
Keyword(s):  
Healthy Men
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