Isolation oflactobacillus reuterifrom Peyer's patches and their effects on sIgA production and gut microbiota diversity

2016 ◽  
Vol 60 (9) ◽  
pp. 2020-2030 ◽  
Author(s):  
Panpan Wang ◽  
Ya Li ◽  
Hang Xiao ◽  
Yonghui Shi ◽  
Guo-wei Le ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Peyer's Patches ◽  
Peyer’S Patches ◽  
Microbiota Diversity

scholarly journals Mucosal immunity–mediated modulation of the gut microbiome by oral delivery of probiotics into Peyer’s patches

2021 ◽  
Vol 7 (20) ◽  
pp. eabf0677
Author(s):  
Sisi Lin ◽  
Subhajit Mukherjee ◽  
Juanjuan Li ◽  
Weiliang Hou ◽  
Chao Pan ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Bacterial Translocation ◽  
Mucosal Immunity ◽  
Oral Delivery ◽  
Immunoglobulin A ◽  
Intestinal Barrier ◽  
Peyer's Patches ◽  
Peyer’S Patches ◽  
External Threats ◽  
Microfold Cells

Methods capable of maintaining gut microbiota homeostasis to prevent bacterial translocation and infection under external threats are critical for multiple facets of human health but have been rarely reported. Here, we describe the elicitation of mucosal immunity to modulate the gut microbiota by oral delivery of living probiotics into Peyer’s patches. Probiotics are individually camouflaged within a yeast membrane, on which the embedded β-glucan can facilitate the phagocytosis of microfold cells that locate in the intestinal epithelium. The delivery of probiotics into lymphoid follicles after oral ingestion promotes robust mucosal immune responses and notably upgrades the production of secretory immunoglobulin A. The provoked immunity positively regulates the gut microflora, which, in turn, retains gut homeostasis and provides defense against environmental attacks. In two murine models of gut barrier impairment, oral administration with camouflaged probiotics effectively prevents the breakdown of intestinal barrier and evidences limited bacterial translocation and systemic inflammation.

Post-mortem Peyer’s patches: Their potential application in forensic medicine

2009 ◽  
Vol 00 (00) ◽  
pp. 090513010017019-7
Author(s):  
Biagio Solarino ◽  
Giancarlo Di Vella ◽  
Thea Magrone ◽  
Felicita Jirillo ◽  
Angela Tafaro ◽  
...  
Keyword(s):  
Forensic Medicine ◽  
Potential Application ◽  
Peyer's Patches ◽  
Peyer’S Patches ◽  
Post Mortem

scholarly journals Fibroblastic reticular cell lineage convergence in Peyer’s patches governs intestinal immunity

2021 ◽  
Vol 22 (4) ◽  
pp. 510-519
Author(s):  
Alejandro Prados ◽  
Lucas Onder ◽  
Hung-Wei Cheng ◽  
Urs Mörbe ◽  
Mechthild Lütge ◽  
...  
Keyword(s):  
Cell Lineage ◽  
Peyer's Patches ◽  
Peyer’S Patches ◽  
Reticular Cell ◽  
Intestinal Immunity ◽  
Fibroblastic Reticular Cell

scholarly journals HMGB1 promotes CXCL12‐dependent egress of murine B cells from Peyer's patches in homeostasis

2021 ◽  
Author(s):  
Lorenzo Spagnuolo ◽  
Viola Puddinu ◽  
Noémie Boss ◽  
Thibaud Spinetti ◽  
Anne Oberson ◽  
...  
Keyword(s):  
B Cells ◽  
Peyer's Patches ◽  
Peyer’S Patches

scholarly journals Effect of TU‐100 on Peyer's patches in a bacterial translocation rat model

2021 ◽  
Author(s):  
Chie Takasu ◽  
Katsuki Miyazaki ◽  
Kozo Yoshikawa ◽  
Masaaki Nishi ◽  
Takuya Tokunaga ◽  
...  
Keyword(s):  
Bacterial Translocation ◽  
Rat Model ◽  
Peyer's Patches ◽  
Peyer’S Patches
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