Modulation of gut microbiota in rats fed high-fat diets by processing whole-grain barley to barley malt

2015 ◽  
Vol 59 (10) ◽  
pp. 2066-2076 ◽  
Author(s):  
Yadong Zhong ◽  
Margareta Nyman ◽  
Frida Fåk
Keyword(s):  
Gut Microbiota ◽  
Whole Grain ◽  
High Fat ◽  
Barley Malt ◽  
High Fat Diets ◽  
Fat Diets

scholarly journals Monovalerin and trivalerin increase brain acetic acid, decrease liver succinic acid, and alter gut microbiota in rats fed high-fat diets

2018 ◽  
Vol 58 (4) ◽  
pp. 1545-1560 ◽  
Author(s):  
Thao Duy Nguyen ◽  
Olena Prykhodko ◽  
Frida Fåk Hållenius ◽  
Margareta Nyman
Keyword(s):  
Acetic Acid ◽  
Gut Microbiota ◽  
Succinic Acid ◽  
High Fat ◽  
High Fat Diets ◽  
Fat Diets

Gut microbiota mediates the protective effects of dietary β‐hydroxy‐β‐methylbutyrate (HMB) against obesity induced by high‐fat diets

2019 ◽  
Vol 33 (9) ◽  
pp. 10019-10033 ◽  
Author(s):  
Yehui Duan ◽  
Yinzhao Zhong ◽  
Hao Xiao ◽  
Changbing Zheng ◽  
Bo Song ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Protective Effects ◽  
High Fat ◽  
High Fat Diets ◽  
Fat Diets

scholarly journals High-Fat Diets with Differential Fatty Acids Induce Obesity and Perturb Gut Microbiota in Honey Bee

2021 ◽  
Vol 22 (2) ◽  
pp. 834
Author(s):  
Xiaofei Wang ◽  
Zhaopeng Zhong ◽  
Xiangyin Chen ◽  
Ziyun Hong ◽  
Weimin Lin ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Honey Bee ◽  
Dietary Fat ◽  
Honey Bees ◽  
High Fat Diet ◽  
Dietary Fats ◽  
High Fat ◽  
High Fat Diets ◽  
Fat Diets ◽  
Host Metabolism

HFD (high-fat diet) induces obesity and metabolic disorders, which is associated with the alteration in gut microbiota profiles. However, the underlying molecular mechanisms of the processes are poorly understood. In this study, we used the simple model organism honey bee to explore how different amounts and types of dietary fats affect the host metabolism and the gut microbiota. Excess dietary fat, especially palm oil, elicited higher weight gain, lower survival rates, hyperglycemic, and fat accumulation in honey bees. However, microbiota-free honey bees reared on high-fat diets did not significantly change their phenotypes. Different fatty acid compositions in palm and soybean oil altered the lipid profiles of the honey bee body. Remarkably, dietary fats regulated lipid metabolism and immune-related gene expression at the transcriptional level. Gene set enrichment analysis showed that biological processes, including transcription factors, insulin secretion, and Toll and Imd signaling pathways, were significantly different in the gut of bees on different dietary fats. Moreover, a high-fat diet increased the relative abundance of Gilliamella, while the level of Bartonella was significantly decreased in palm oil groups. This study establishes a novel honey bee model of studying the crosstalk between dietary fat, gut microbiota, and host metabolism.

Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects

2015 ◽  
Vol 6 (9) ◽  
pp. 3165-3176 ◽  
Author(s):  
Yadong Zhong ◽  
Cristina Teixeira ◽  
Nittaya Marungruang ◽  
Watina Sae-Lim ◽  
Eden Tareke ◽  
...  
Keyword(s):  
Butyric Acid ◽  
Tight Junction Proteins ◽  
High Fat ◽  
Advanced Glycation ◽  
Barley Malt ◽  
Glycation End Products ◽  
High Fat Diets ◽  
End Products ◽  
Fat Diets ◽  
Junction Proteins

Barley malt has been shown to give high levels of butyric acid in the cecum and serum of rats.

scholarly journals Reframing Nutritional Microbiota Studies To Reflect an Inherent Metabolic Flexibility of the Human Gut: a Narrative Review Focusing on High-Fat Diets

mBio ◽  
2021 ◽  
Vol 12 (2) ◽  
Author(s):  
Jonathan Sholl ◽  
Lucy J. Mailing ◽  
Thomas R. Wood
Keyword(s):  
Gut Microbiota ◽  
Food Sources ◽  
Metabolic Flexibility ◽  
Gut Health ◽  
High Fat ◽  
Human Gut ◽  
Ketogenic Diets ◽  
High Fat Diets ◽  
Fat Diets ◽  
Secondary Bile Acids

ABSTRACT There is a broad consensus in nutritional-microbiota research that high-fat (HF) diets are harmful to human health, at least in part through their modulation of the gut microbiota. However, various studies also support the inherent flexibility of the human gut and our microbiota’s ability to adapt to a variety of food sources, suggesting a more nuanced picture. In this article, we first discuss some problems facing basic translational research and provide a different framework for thinking about diet and gut health in terms of metabolic flexibility. We then offer evidence that well-formulated HF diets, such as ketogenic diets, may provide healthful alternative fuel sources for the human gut. We place this in the context of cancer research, where this concern over HF diets is also expressed, and consider various potential objections concerning the effects of lipopolysaccharides, trimethylamine-N-oxide, and secondary bile acids on human gut health. We end by providing some general suggestions for how to improve research and clinical practice with respect to the gut microbiota when considering the framework of metabolic flexibility.

scholarly journals Gut bacteria formation and influencing factors

2021 ◽  
Author(s):  
Jing Yang ◽  
Jin'en Wu ◽  
Yating Li ◽  
Yong'e Zhang ◽  
William C Cho ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Human Health ◽  
Large Scale ◽  
Geographic Location ◽  
Gut Bacteria ◽  
High Fat ◽  
Modern Life ◽  
Antibacterial Drugs ◽  
High Fat Diets ◽  
Fat Diets

Abstract The gut microbiota plays an important role in human health. In modern life, with the improvement of living conditions, the intake of high-sugar and high-fat diets as well as the large-scale use of antibacterial drugs have an extensive impact on the gut microbiota, even leading to gut microbiota-orchestrating disorders. This review discusses the effects of various factors, including geographic location, age, diet, antibacterial drugs, psychological situation and exercise on gut bacteria, which helps us profoundly to understand the significance of gut bacteria to human health and to find effective solutions to prevent or treat related diseases.

Effects of potato dextrin on the composition and metabolism of the gut microbiota in rats fed standard and high-fat diets

2017 ◽  
Vol 34 ◽  
pp. 398-407 ◽  
Author(s):  
Renata Barczynska ◽  
Adam Jurgoński ◽  
Katarzyna Slizewska ◽  
Jerzy Juśkiewicz ◽  
Janusz Kapusniak
Keyword(s):  
Gut Microbiota ◽  
High Fat ◽  
High Fat Diets ◽  
Fat Diets
Sign in / Sign up

Export Citation Format

Share Document