Dyskinesia‐inducing lead contacts optimize outcome of subthalamic stimulation in Parkinson's disease

2019 ◽  
Vol 34 (11) ◽  
pp. 1728-1734 ◽  
Author(s):  
Walid Bouthour ◽  
Matthieu Béreau ◽  
Astrid Kibleur ◽  
André Zacharia ◽  
Emilie Tomkova Chaoui ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Stimulation

Modulation of motor cortex by subthalamic stimulation in Parkinson's disease

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
B Haslinger ◽  
K Kalteis ◽  
F Alesch ◽  
H Boecker ◽  
AO Ceballos-Baumann
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Cortex ◽  
Subthalamic Stimulation

Comparison of Pallidal and Subthalamic Stimulation on Force Control in Patient's with Parkinson's Disease

Motor Control ◽  
2004 ◽  
Vol 8 (4) ◽  
pp. 484-499 ◽  
Author(s):  
Jay L. Alberts ◽  
Christopher M. Elder ◽  
Michael S. Okun ◽  
Jerrold L. Vitek
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Force Control ◽  
Subthalamic Stimulation

scholarly journals Short-term quality of life after subthalamic stimulation depends on non-motor symptoms in Parkinson's disease

2018 ◽  
Vol 11 (4) ◽  
pp. 867-874 ◽  
Author(s):  
Haidar Salimi Dafsari ◽  
Luisa Weiß ◽  
Monty Silverdale ◽  
Alexandra Rizos ◽  
Prashanth Reddy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Short Term ◽  
Subthalamic Stimulation ◽  
Non Motor Symptoms

scholarly journals Bilateral but not unilateral subthalamic stimulation promotes apathy: a translational study in rodents and Parkinson’s disease patients

2020 ◽  
Author(s):  
Yvan Vachez ◽  
Marie Bahout ◽  
Robin Magnard ◽  
Pierre-Maxime David ◽  
Carole Carcenac ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Acute Effect ◽  
Recent Experimental Data ◽  
Translational Study ◽  
Clinical Center ◽  
Subthalamic Stimulation ◽  
Operative Assessment ◽  
Stn Dbs

ABSTRACTApathy is frequently reported in Parkinson’s disease (PD) patients under subthalamic nucleus deep brain stimulation (STN-DBS). The prevailing clinical view for apathy following STN-DBS is the reduction of dopaminergic medication. However, few clinical reports and recent experimental data suggested the pathogenicity of bilateral STN-DBS on motivation, challenging the leading opinion. Here, we investigate whether bilateralism of STN-DBS influences apathy outcome after STN-DBS, combining pre-clinical and clinical approaches. We assess the motivational effects of chronic unilateral STN-DBS in rats in the exact same conditions having highlighted a loss of motivation under bilateral STN-DBS. Clinical data are obtained by the follow-up of a cohort of parkinsonian patients undergoing unilateral STN-DBS and coming from the clinical center that described apathy related to bilateral STN-DBS itself. Despite an acute effect, which fades rapidly, unilateral STN-DBS did not induce a loss of motivation reminiscent to apathy in rats. In patients, apathy did not increase between the preoperative and the post-operative assessment. Together, those data demonstrate that bilateral but not unilateral STN-DBS can induce a loss of motivation in both rats and patients. This constitutes another evidence of the role of STN-DBS itself for apathy in PD.

Sex, Food and Threat: Startling Changes after Subthalamic Stimulation in Parkinson's Disease

2013 ◽  
Vol 6 (5) ◽  
pp. 740-745 ◽  
Author(s):  
Tereza Serranová ◽  
Tomáš Sieger ◽  
Petr Dušek ◽  
Filip Růžička ◽  
Dušan Urgošík ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Stimulation

scholarly journals Bilateral subthalamic stimulation impairs cognitive-motor performance in Parkinson's disease patients

Brain ◽  
2008 ◽  
Vol 131 (12) ◽  
pp. 3348-3360 ◽  
Author(s):  
J. L. Alberts ◽  
C. Voelcker-Rehage ◽  
K. Hallahan ◽  
M. Vitek ◽  
R. Bamzai ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Performance ◽  
Subthalamic Stimulation

Voice acoustic changes during bilateral subthalamic stimulation in patients with Parkinson's disease

2011 ◽  
Vol 113 (3) ◽  
pp. 188-195 ◽  
Author(s):  
István Valálik ◽  
György Smehák ◽  
László Bognár ◽  
András Csókay
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Stimulation

Pre-operative obesity may influence subthalamic stimulation outcome in Parkinson's disease

2015 ◽  
Vol 359 (1-2) ◽  
pp. 260-265 ◽  
Author(s):  
Audrey Rouillé ◽  
Stéphane Derrey ◽  
Romain Lefaucheur ◽  
Alaina Borden ◽  
Damien Fetter ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Stimulation
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