Future directions in the treatment of Parkinson's disease

2007 ◽  
Vol 22 (S17) ◽  
pp. S385-S391 ◽  
Author(s):  
Anthony H.V. Schapira
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Future Directions

scholarly journals An Innovative Personalised Management Program for Older Adults with Parkinson’s Disease: New Concepts and Future Directions

2021 ◽  
Vol 11 (1) ◽  
pp. 43
Author(s):  
Piyush Varma ◽  
Lakshanaa Narayan ◽  
Jane Alty ◽  
Virginia Painter ◽  
Chandrasekhara Padmakumar
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Older Persons ◽  
Clinical Manifestations ◽  
Clinical Syndrome ◽  
Management Program ◽  
Older Person ◽  
Care Needs ◽  
Future Directions ◽  
New Concepts

Introduction: Parkinson’s disease is a heterogeneous clinical syndrome. Parkinson’s disease in older persons presents with a diverse array of clinical manifestations leading to unique care needs. This raises the need for the healthcare community to proactively address the care needs of older persons with Parkinson’s disease. Though it is tempting to categorise different phenotypes of Parkinson’s disease, a strong evidence based for the same is lacking. There is considerable literature describing the varying clinical manifestations in old age. This article aims to review the literature looking for strategies in personalising the management of an older person with Parkinson’s disease.

Air pollution and Parkinson’s disease – evidence and future directions

2017 ◽  
Vol 32 (4) ◽  
Author(s):  
Natalia Palacios
Keyword(s):  
Parkinson’S Disease ◽  
Air Pollution ◽  
Parkinson's Disease ◽  
Genetic Factors ◽  
Brain Inflammation ◽  
Unknown Etiology ◽  
Future Directions ◽  
Air Pollution Exposure ◽  
Pollution Exposure ◽  
And Oxidative Stress

AbstractParkinson’s disease (PD) is a neurodegenerative disease of unknown etiology that is thought to be caused by a complex combination of environmental and/or genetic factors. Air pollution exposure is linked to numerous adverse effects on human health, including brain inflammation and oxidative stress, processes that are believed to contribute to the development and progression of PD. This review provides an overview of recent advances in the epidemiology of air pollution and PD, including evidence of the effects of various pollutants (ozone, PM

scholarly journals Distress in Parkinson's disease: Contributions of disease factors and metacognitive style

2005 ◽  
Vol 187 (2) ◽  
pp. 182-183 ◽  
Author(s):  
Rory Allott ◽  
Adrian Wells ◽  
Anthony P. Morrison ◽  
Richard Walker
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Psychological Factor ◽  
Psychological Interventions ◽  
Depression And Anxiety ◽  
Future Directions ◽  
Related Risk

SummaryResearch has suggested that the high levels of depression and anxiety observed in Parkinson's disease are a primary consequence of its pathophysiology. This study aimed to test the hypothesis that a psychological factor, metacognitive style, is significantly associated with distress, independent of previously identified disease-related risk factors. Distress, metacognitive style and disease factors were assessed in 44 people with a diagnosis of Parkinson's disease. People with a specific metacognitive style had an increased vulnerability to distress over and above previously identified disease factors; this suggests future directions for the development of psychological interventions.

Palliative care for Parkinson’s disease: A summary of the evidence and future directions

2013 ◽  
Vol 27 (9) ◽  
pp. 805-810 ◽  
Author(s):  
Edward W Richfield ◽  
Edward JS Jones ◽  
Jane E Alty
Keyword(s):  
Parkinson’S Disease ◽  
Palliative Care ◽  
Parkinson's Disease ◽  
Future Directions

scholarly journals Optimizing Cognitive Training for the Treatment of Cognitive Dysfunction in Parkinson’s Disease: Current Limitations and Future Directions

2021 ◽  
Vol 13 ◽  
Author(s):  
Bianca Guglietti ◽  
David Hobbs ◽  
Lyndsey E. Collins-Praino
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Dysfunction ◽  
Cognitive Training ◽  
Assistive Technologies ◽  
Motor Impairments ◽  
Future Directions ◽  
Cognitive Domains ◽  
Current State ◽  
Non Motor Symptoms

Cognitive dysfunction, primarily involving impairments in executive function, visuospatial function and memory, is one of the most common non-motor symptoms of Parkinson’s disease (PD). Currently, the only pharmacological treatments available for the treatment of cognitive dysfunction in PD provide variable benefit, making the search for potential non-pharmacological therapies to improve cognitive function of significant interest. One such therapeutic strategy may be cognitive training (CT), which involves the repetition of standardized tasks with the aim of improving specific aspects of cognition. Several studies have examined the effects of CT in individuals with PD and have shown benefits in a variety of cognitive domains, but the widespread use of CT in these individuals may be limited by motor impairments and other concerns in study design. Here, we discuss the current state of the literature on the use of CT for PD and propose recommendations for future implementation. We also explore the potential use of more recent integrative, adaptive and assistive technologies, such as virtual reality, which may optimize the delivery of CT in PD.

Proteomics in Human Parkinson’s Disease: Present Scenario and Future Directions

2019 ◽  
Vol 39 (7) ◽  
pp. 901-915 ◽  
Author(s):  
Anubhuti Dixit ◽  
Rachna Mehta ◽  
Abhishek Kumar Singh
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Future Directions ◽  
Disease Present
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