Rasagiline improves quality of life in patients with early Parkinson's disease

2006 ◽  
Vol 21 (5) ◽  
pp. 616-623 ◽  
Author(s):  
Kevin M. Biglan ◽  
Steven Schwid ◽  
Shirley Eberly ◽  
Karen Blindauer ◽  
Stanley Fahn ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Parkinson’S Disease

IMPACT & TREATMENT OF NON-MOTOR SYMPTOMS IN EARLY PARKINSON'S DISEASE

2015 ◽  
Vol 86 (11) ◽  
pp. e4.80-e4
Author(s):  
Fahd Baig ◽  
Michael Lawton ◽  
Michal Rolinski ◽  
Claudio Ruffmann ◽  
Kannan Nithi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

ObjectiveTo delineate treatment and quality of life of non-motor symptoms (NMS) in early Parkinson's disease (PD) and first-degree relatives.BackgroundNon-motor symptoms (NMS) are an important prodromal feature of Parkinson's disease (PD). However, their frequency, treatment rates and impact on health-related quality of life (HRQoL) in the early motor phase is unclear.Methods769 population-ascertained PD subjects within 3.5 years of diagnosis and 287 control subjects were assessed. Validated severity questionnaires were employed to assess NMS symptoms across the following domains: (1) neuropsychiatric (2) gastrointestinal (3) sleep (4) sensory (5) autonomic (6) sexual. Health related quality of life (HRQoL), functional status and management were also evaluated.ResultsNMS were common in early PD. More than half of the PD cases had hyposmia, pain, fatigue, sleep disturbance or urinary dysfunction. PD cases had worse HRQoL scores than controls (OR 4.1, p<0.001) with depression, anxiety and pain being stronger drivers than MDS-UPDRS motor scores. Quality of life is affected in early PD, although 23% of participants reported no problems. NMS were rarely treated in routine clinical practice.ConclusionsDespite their major impact on HRQoL, NMS are usually under-recognised and treated. The use of screening tools could improve recognition and treatment of NMS in early PD.

Non‐motor symptoms in early Parkinson's disease with different motor subtypes and their associations with quality of life

2018 ◽  
Vol 26 (3) ◽  
pp. 400-406 ◽  
Author(s):  
X. Huang ◽  
S. Y.‐E. Ng ◽  
N. S.‐Y. Chia ◽  
F. Setiawan ◽  
K.‐Y. Tay ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

scholarly journals Quality of Life and Mild Cognitive Impairment in Early Parkinson’s Disease: Does Subtype Matter?

2015 ◽  
Vol 4 (3) ◽  
pp. 331-336 ◽  
Author(s):  
Rachael A. Lawson ◽  
Alison J. Yarnall ◽  
Gordon W. Duncan ◽  
Tien K. Khoo ◽  
David P. Breen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Early Parkinson’S Disease

Quality of life in early Parkinson's disease: Impact of dyskinesias and motor fluctuations

2003 ◽  
Vol 19 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Connie Marras ◽  
Anthony Lang ◽  
Murray Krahn ◽  
George Tomlinson ◽  
Gary Naglie ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Fluctuations ◽  
Disease Impact ◽  
Early Parkinson’S Disease

scholarly journals Multimorbidity Predicts Quality of Life but not Motor Severity in Early Parkinson’s Disease

2018 ◽  
Vol 8 (4) ◽  
pp. 511-515 ◽  
Author(s):  
Rhys Gravell ◽  
Gordon W. Duncan ◽  
Tien K. Khoo ◽  
David J. Burn ◽  
Avan A. Sayer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Parkinson’S Disease

scholarly journals Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life

2014 ◽  
Vol 20 (10) ◽  
pp. 1071-1075 ◽  
Author(s):  
Rachael A. Lawson ◽  
Alison J. Yarnall ◽  
Gordon W. Duncan ◽  
Tien K. Khoo ◽  
David P. Breen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Early Parkinson’S Disease
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