Late-Onset neurodegeneration with brain iron accumulation type 1: Expanding the clinical spectrum

2001 ◽  
Vol 16 (6) ◽  
pp. 1148-1152 ◽  
Author(s):  
Brad A. Racette ◽  
Arie Perry ◽  
Giovanni D'Avossa ◽  
Joel S. Perlmutter
Keyword(s):  
Late Onset ◽  
Clinical Spectrum ◽  
Iron Accumulation ◽  
Brain Iron

The neuropathology of neurodegeneration with brain iron accumulation, type 1 (NBIA 1) contains insoluble α-synuclean

2000 ◽  
Vol 21 ◽  
pp. 65
Author(s):  
James E. Galvin ◽  
Benoit I. Giasson ◽  
Pierluigi L. Gambetti ◽  
Virginia My Lee ◽  
John Q. Trojanowski
Keyword(s):  
Iron Accumulation ◽  
Brain Iron

α-Synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies

2000 ◽  
Vol 100 (5) ◽  
pp. 568-574 ◽  
Author(s):  
Manuela Neumann ◽  
Silke Adler ◽  
Oliver Schlüter ◽  
Elisabeth Kremmer ◽  
Reiner Benecke ◽  
...  
Keyword(s):  
Lewy Bodies ◽  
Iron Accumulation ◽  
Brain Iron

scholarly journals Neurodegeneration With Brain Iron Accumulation (NBIA) Syndromes Presenting With Late-Onset Craniocervical Dystonia: An Illustrative Case Series‎

2016 ◽  
Vol 4 (2) ◽  
pp. 254-257 ◽  
Author(s):  
Florian Brugger ◽  
Georg Kägi ◽  
Massimo Pandolfo ◽  
Niccolò E. Mencacci ◽  
Amit Batla ◽  
...  
Keyword(s):  
Late Onset ◽  
Iron Accumulation ◽  
Illustrative Case ◽  
Brain Iron ◽  
Craniocervical Dystonia

Intrathecal Morphine Therapy in the Management of Status Dystonicus in Neurodegeneration Brain Iron Accumulation Type 1

2015 ◽  
Vol 50 (2) ◽  
pp. 94-98 ◽  
Author(s):  
William Omar Contreras Lopez ◽  
Humberto Kluge Schroeder ◽  
Iuri Santana Neville ◽  
Manoel Jacobsen Teixeira ◽  
Danilo Costa Barbosa ◽  
...  
Keyword(s):  
Intrathecal Morphine ◽  
Iron Accumulation ◽  
Brain Iron ◽  
Status Dystonicus ◽  
Morphine Therapy

scholarly journals Late Onset Neurodegeneration with Brain-Iron Accumulation Presenting as Parkinsonism

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Robert Fekete
Keyword(s):  
Differential Diagnosis ◽  
Neurodegenerative Disorders ◽  
Late Onset ◽  
Iron Accumulation ◽  
Atypical Parkinsonism ◽  
Brain Iron ◽  
Dopamine Transporter Imaging ◽  
Mri Brain ◽  
Abnormal Brain ◽  
Brain Iron Deposition

Neurodegeneration with brain-iron accumulation (NBIA) encompasses a family of neurodegenerative disorders connected by evidence of abnormal brain iron deposition. Advances in imaging and genetic testing expanded the clinical spectrum of these disorders. Here, a case of parkinsonism and dystonia with orofacial stereotypies is presented. While the patient was initially diagnosed with Parkinson’s disease and placed on levodopa therapy, dopamine transporter imaging via (123)I-FP-CIT SPECT (DaTSCAN) was normal. MRI brain showed “eye of the tiger” sign on T2 weighted imaging. NBIA should be considered in the differential diagnosis of atypical parkinsonism.

Coexistence of TDP-43 and tau pathology in neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome)

2011 ◽  
Vol 31 (5) ◽  
pp. 531-539 ◽  
Author(s):  
Takashi Haraguchi ◽  
Seishi Terada ◽  
Hideki Ishizu ◽  
Osamu Yokota ◽  
Hidenori Yoshida ◽  
...  
Keyword(s):  
Iron Accumulation ◽  
Brain Iron ◽  
Tau Pathology

Bilateral Subthalamic Nucleus Stimulation in the Treatment of Neurodegeneration with Brain Iron Accumulation Type 1

2011 ◽  
Vol 89 (3) ◽  
pp. 162-166 ◽  
Author(s):  
Ming Ge ◽  
Kai Zhang ◽  
Yu Ma ◽  
Fan-gang Meng ◽  
Wen-han Hu ◽  
...  
Keyword(s):  
Subthalamic Nucleus ◽  
Iron Accumulation ◽  
Brain Iron ◽  
Subthalamic Nucleus Stimulation

scholarly journals Neurodegeneration with Brain Iron Accumulation, Type 1 Is Characterized by α-, β-, and γ-Synuclein Neuropathology

2000 ◽  
Vol 157 (2) ◽  
pp. 361-368 ◽  
Author(s):  
James E. Galvin ◽  
Benoit Giasson ◽  
Howard I. Hurtig ◽  
Virginia M.-Y. Lee ◽  
John Q. Trojanowski
Keyword(s):  
Iron Accumulation ◽  
Brain Iron

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for  -synuclein

Neurology ◽  
1998 ◽  
Vol 51 (3) ◽  
pp. 887-889 ◽  
Author(s):  
S. Arawaka ◽  
Y. Saito ◽  
S. Murayama ◽  
H. Mori
Keyword(s):  
Lewy Body ◽  
Iron Accumulation ◽  
Brain Iron
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