scholarly journals Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors

2017 ◽  
Vol 56 (7) ◽  
pp. 1733-1742 ◽  
Author(s):  
Rong Wang ◽  
Ying-Shiuan Chen ◽  
Wan-Mohaiza Dashwood ◽  
Qingjie Li ◽  
Christiane V. Löhr ◽  
...  
Keyword(s):  
Cell Viability ◽  
Skin Tumors ◽  
Rat Skin ◽  
P120 Catenin ◽  
Altered Cell

scholarly journals Pulsed Low-Frequency Magnetic Fields Induce Tumor Membrane Disruption and Altered Cell Viability

2020 ◽  
Vol 118 (7) ◽  
pp. 1552-1563 ◽  
Author(s):  
Christopher P. Ashdown ◽  
Scott C. Johns ◽  
Edward Aminov ◽  
Michael Unanian ◽  
William Connacher ◽  
...  
Keyword(s):  
Magnetic Fields ◽  
Cell Viability ◽  
Low Frequency ◽  
Membrane Disruption ◽  
Altered Cell

Effects of calcium antagonists on cyclic AMP phosphodiesterase induction in Dictyostelium discoideum

1987 ◽  
Vol 88 (3) ◽  
pp. 379-388
Author(s):  
M.B. Coukell ◽  
A.M. Cameron
Keyword(s):  
Cyclic Amp ◽  
Cell Viability ◽  
Dictyostelium Discoideum ◽  
Cyclic Gmp ◽  
Cell Shape ◽  
Second Messengers ◽  
Channel Blockers ◽  
Cyclic Amp Phosphodiesterase ◽  
Dose Dependent Fashion ◽  
Altered Cell

Previous studies have suggested that cyclic GMP and/or Ca2+ might function as second messengers in the induction by exogenous cyclic AMP of the cyclic AMP phosphodiesterase (PD) in Dictyostelium discoideum. To assess further the role of Ca2+ in PD induction we examined the effect on this process of a number of putative Ca2+-channel blockers. At relatively low micromolar concentrations, TMB-8, nicardipine, nifedipine, diltiazem and verapamil all altered cell shape and inhibited PD induction in a similar dose-dependent fashion. Concentrations of these drugs that abolished PD induction had no effect on cell viability; however, higher concentrations reduced viability and caused cell lysis. All effects of these compounds on the cells were antagonized at least partially by 5–10 mM-Ca2+. Other cations tested were considerably less effective. Like the organic inhibitors, La3+ also altered cell shape, inhibited PD induction and reduced cell viability at elevated concentrations, but its effect on the cells appeared to be more complex. Inhibition of PD induction by the organic antagonists could not be attributed solely to an impaired uptake of extracellular Ca2+, a reduction of ATP pools in the cells or a direct effect on calmodulin. Concentrations of TMB-8 that inhibited PD induction had little effect on the cyclic GMP response. Therefore, this compound did not inhibit PD induction indirectly by blocking cyclic GMP synthesis.(ABSTRACT TRUNCATED AT 250 WORDS)

Epidermal Cell Viability in Rat Skin Preserved at 4°C

1993 ◽  
Vol 31 (4) ◽  
pp. 358-363 ◽  
Author(s):  
Kazunori Matsuka ◽  
Yuiro Hata ◽  
Kenji Yano ◽  
Osamu Ito ◽  
Hidenori Matsuda
Keyword(s):  
Cell Viability ◽  
Epidermal Cell ◽  
Rat Skin

The Effect of a 24-Hour Fractionation Interval on the Induction of Rat Skin Tumors by Electron Radiation

1975 ◽  
Vol 62 (3) ◽  
pp. 478 ◽  
Author(s):  
F. J. Burns ◽  
R. E. Albert ◽  
I. P. Sinclair ◽  
M. Vanderlaan
Keyword(s):  
Skin Tumors ◽  
Electron Radiation ◽  
Rat Skin

scholarly journals Altered Cell Viability and Proliferation Activity of Peripheral Lymphocytes in Patients with Alzheimer's Disease

2010 ◽  
Vol 7 (1) ◽  
pp. 68 ◽  
Author(s):  
Se Chang Yoon ◽  
Young-Ah Kwon ◽  
Hyeran Kim ◽  
Seonwoo Kim ◽  
Sangmee Ahn Jo ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cell Viability ◽  
Peripheral Lymphocytes ◽  
Proliferation Activity ◽  
Altered Cell
Sign in / Sign up

Export Citation Format

Share Document