scholarly journals Identification and characterization of the cell division protein MapZ from Streptococcus suis

2021 ◽  
Vol 10 (5) ◽  
Author(s):  
Muriel Dresen ◽  
Manfred Rohde ◽  
Jesús Arenas ◽  
Astrid Greeff ◽  
Andreas Nerlich ◽  
...  
Gene ◽  
2004 ◽  
Vol 342 (1) ◽  
pp. 189-197 ◽  
Author(s):  
Eric Altermann ◽  
Logan B. Buck ◽  
Raul Cano ◽  
Todd R. Klaenhammer

2010 ◽  
Vol 140 (1-2) ◽  
pp. 171-175 ◽  
Author(s):  
Anding Zhang ◽  
Xiaofeng Mu ◽  
Bo Chen ◽  
Cheng Liu ◽  
Li Han ◽  
...  

2009 ◽  
Vol 47 (5) ◽  
pp. 267-273 ◽  
Author(s):  
Xue-han Zhang ◽  
Kong-wang He ◽  
Zhi-tao Duan ◽  
Jun-ming Zhou ◽  
Zheng-yu Yu ◽  
...  

1996 ◽  
Vol 19 (3) ◽  
pp. 599-609 ◽  
Author(s):  
Ruairí A. Mac Síomóin ◽  
Noboru Nakata ◽  
Tatuo Murai ◽  
Masanosuke Yoshikawa ◽  
Hiroyuki Tsuji ◽  
...  

2019 ◽  
Author(s):  
Jinhua Li ◽  
Ziqi Yan ◽  
Hongmei Li ◽  
Qiong Shi ◽  
Linfang Huang ◽  
...  

ABSTRACTMitosis has long been a therapeutic target for the treatment of cancer. After conducting a phenotypic screen for anti-mitotic activity in a crude extract library of more than 2000 medicinal plants, we identified the rhizomes of Corydalis longicalcarata. Guided by the bioactivity-based assay, two benzophenanthridine alkaloids were purified and subsequently identified as corynoline and its close analog acetylcorynoline. This study uncovers a previously unknown antimitotic activity for these two phytochemicals, discovers their potential to be developed as anticancer drugs, and highlights their pleiotropic effects on cell division, including prevention of chromosome congression, compromise of spindle checkpoint response, and blockage of cytokinesis.


2001 ◽  
Vol 40 (1) ◽  
pp. 115-125 ◽  
Author(s):  
Andrea Feucht ◽  
Isabelle Lucet ◽  
Michael D. Yudkin ◽  
Jeffery Errington

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