Supramolecular Aggregates of Water Soluble Dendritic Polyglycerol Architectures for the Solubilization of Hydrophobic Compounds

2010 ◽  
Vol 31 (17) ◽  
pp. 1516-1520 ◽  
Author(s):  
Indah N. Kurniasih ◽  
Hua Liang ◽  
Jürgen P. Rabe ◽  
Rainer Haag
Keyword(s):  
Water Soluble ◽  
Hydrophobic Compounds ◽  
Supramolecular Aggregates

scholarly journals Organic supramolecular aggregates based on water‐soluble cyclodextrins and calixarenes

Aggregate ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 31-44
Author(s):  
Zhixue Liu ◽  
Xianyin Dai ◽  
Yonghui Sun ◽  
Yu Liu
Keyword(s):  
Water Soluble ◽  
Supramolecular Aggregates

Amphiphilic Functionalized Montmorillonite as Possible Carriers for Hydrophobic Compounds

2019 ◽  
Vol 956 ◽  
pp. 260-269
Author(s):  
Ke Xuan Shen ◽  
Shi Yong Sun ◽  
Ke Wang ◽  
Biao Biao Ma ◽  
Fa Qin Dong ◽  
...  
Keyword(s):  
Water Soluble ◽  
X Ray Diffraction ◽  
Excellent Performance ◽  
Model Compounds ◽  
X Ray ◽  
Hydrophobic Compounds ◽  
Poorly Water Soluble ◽  
Contact Angle Analysis ◽  
Carrier Systems ◽  
Scanning Electron

Amphiphilic functionalized montmorillonite (MMT) has been employed in hydrophobic compounds delivery systems. In the present study, MMT intercalated by 3-aminopropyl trimethoxysilane (APS) was employed for the delivery of the model compounds of resveratrol (RSV). The structure and surface morphology of APS-MMT were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, thermogravimetry, scanning electron microscopy, and contact angle analysis. The loading and release efficiencies of RSV were also investigated. Our study showed that the aminosilane-modified MMT is promising for use in poorly water-soluble compounds carrier systems owing to their natural and excellent performance.

Folded alkyl chains in water-soluble capsules and cavitands

2014 ◽  
Vol 12 (34) ◽  
pp. 6561-6563 ◽  
Author(s):  
Jesse V. Gavette ◽  
Kang-Da Zhang ◽  
Dariush Ajami ◽  
Julius Rebek
Keyword(s):  
Water Soluble ◽  
Alkyl Chains ◽  
Hydrophobic Compounds

A deep cavitand with ionic “feet” dimerizes around hydrophobic compounds in D2O.

Bioactive Nanoparticles The Complexation of Odorant Compounds with a-and b-Cyclodextrin

2008 ◽  
Vol 59 (2) ◽  
pp. 149-153 ◽  
Author(s):  
Adrian Rivis ◽  
Nicoleta Gabriela Hadaruga ◽  
Daniel Ioan Hadaruga ◽  
Teodor Trasca ◽  
Marioara Druga ◽  
...  
Keyword(s):  
Thermogravimetric Analysis ◽  
Environmental Factors ◽  
Water Solution ◽  
Point Of View ◽  
Water Soluble ◽  
Linalyl Acetate ◽  
Molecular Encapsulation ◽  
Hydrophobic Compounds ◽  
Bioactive Properties ◽  
Long Life

This paper presents the molecular encapsulation of some odorant compounds in a- or b-cyclodextrin. The molecular encapsulation of hydrophobic compounds in these natural cyclic oligosaccharides provides powders at nano scale with very good protection against degradative environmental factors (temperature, light, moisture, air/oxygen), controlled release of the bioactive compounds (long life bio-action), easy handling of powdery complexes (containing bioactive liquid compounds), higher water soluble bioactive specialties (containing hydrophobic biocompounds). From this point of view, some odorant bionanoparticles with enhanced bioactive properties (protection against oxidation, enhanced olfactive and long life smelling properties) and possible applications in cosmetic and toiletries were obtained and characterized. Both limonene and linalool enantiomers (d and l), dl-linalyl acetate, b-caryophyllene, benzaldehyde, g-decalactone, a-ionone, menthol, vanillin, and hydroxycitronellal were used as guest compounds. The encapsulation was achieved by crystallization from the ethanol-water solution. The GC-MS was used for odorant compound analysis and TG for nanoparticle analysis. a- Cyclodextrin release the odorant compounds earlier then the b-cyclodextrin, as indicated by thermogravimetric analysis. The benzaldehyde, menthol and vanillin were decomplexed at lower temperatures then 70�C and the majority of compounds were complexed at 1:1 stoichiometry ratio.

scholarly journals Mechanism of Uptake of a Cationic Water-Soluble Pyridinium Zinc Phthalocyanine across the Outer Membrane ofEscherichia coli

2000 ◽  
Vol 44 (3) ◽  
pp. 522-527 ◽  
Author(s):  
Andrew Minnock ◽  
David I. Vernon ◽  
Jack Schofield ◽  
John Griffiths ◽  
J. Howard Parish ◽  
...  
Keyword(s):  
Membrane Permeability ◽  
Outer Membrane ◽  
Water Soluble ◽  
Zinc Phthalocyanine ◽  
Permeability Barrier ◽  
E Coli ◽  
Uptake Pathway ◽  
Hydrophobic Compounds ◽  
Cationic Compounds ◽  
Outer Membrane Permeability

ABSTRACT Previous studies have shown that a cationic water-soluble pyridinium zinc phthalocyanine (PPC) is a powerful photosensitizer that is able to inactivate Escherichia coli. In the current work incubation of E. coli cells with PPC in the dark caused alterations in the outer membrane permeability barrier of the cells, rendering the bacteria much more sensitive to hydrophobic compounds, with little effect seen with hydrophilic compounds. Addition of Mg2+ to the medium prior to incubation of the cells with PPC prevented these alterations in the outer membrane permeability barrier. The presence of Mg2+ in the medium also prevented the photoinactivation of E. coli cells with PPC. These results are consistent with the hypothesis that PPC gains access across the outer membrane of E. coli cells via the self-promoted uptake pathway, a mechanism of uptake postulated for the uptake of other cationic compounds across the outer membranes of gram-negative bacteria.

Preliminary Research on the Interaction between a Novel Designed Self-Assembling Peptide with Half-Sequence Ionic Complement and the Natural Product Psoralen

2012 ◽  
Vol 550-553 ◽  
pp. 1580-1585
Author(s):  
Li Li Tang ◽  
Fu Yi Guan ◽  
Dao Hang He
Keyword(s):  
Natural Product ◽  
Pure Water ◽  
Water Soluble ◽  
The Self ◽  
Peptide Sequence ◽  
Force Microscopy ◽  
Self Assembling ◽  
Hydrophobic Compounds ◽  
Atomic Force ◽  
Preliminary Research

This paper describes a new kind of 9-residue half-sequence ionic-complementary peptide P-X7-P, which can spontaneously self-assemble into well-ordered and long interconnected nanofibrilar network structure in pure water, and can be used as a hydrophobic compounds carrier. Psoralen, a natural product, is slight water soluble but has various treatments in medicine. In order to fully understand the interaction between the self-assembling peptide and psoralen,the nanostructures formed by two of them were characterized by atomic force microscopy (AFM), field-emission scanning electron microscopy (FE-SEM). This work provides insights on the interaction between the amphiphilic self-assembling peptide and psoralen that are useful for the bottom up development of peptide sequence for local natural product drug delivery applications.

scholarly journals Encapsulation of biocides by cyclodextrins: toward synergistic effects against pathogens

2014 ◽  
Vol 10 ◽  
pp. 2603-2622 ◽  
Author(s):  
Véronique Nardello-Rataj ◽  
Loïc Leclercq
Keyword(s):  
Drug Delivery ◽  
Complex Systems ◽  
Inclusion Complexes ◽  
Antimicrobial Agents ◽  
Synergistic Effects ◽  
Water Soluble ◽  
Future Directions ◽  
Research Areas ◽  
Hydrophobic Compounds ◽  
Soluble Complexes

Host–guest chemistry is useful for the construction of nanosized objects. Some of the widely used hosts are probably the cyclodextrins (CDs). CDs can form water-soluble complexes with numerous hydrophobic compounds. They have been widespread used in medicine, drug delivery and are of interest for the biocides encapsulation. Indeed, this enables the development of more or less complex systems that release antimicrobial agents with time. In this paper, the general features of CDs and their applications in the field of biocides have been reviewed. As the key point is the formation of biocide–CD inclusion complexes, this review deals with this in depth and the advantages of biocide encapsulation are highlighted throughout several examples from the literature. Finally, some future directions of investigation have been proposed. We hope that scientists studying biocide applications receive inspiration from this review to exploit the opportunities offered by CDs in their respective research areas.

A Resorcinol-Formaldehyde Resin as an Embedding Material for Electron Microscopy of Membranes

1969 ◽  
Vol 27 ◽  
pp. 328-329 ◽  
Author(s):  
J. G. Robertson ◽  
D. F. Parsons
Keyword(s):  
Electron Microscopy ◽  
Osmium Tetroxide ◽  
Neutral Lipids ◽  
Lipid Extraction ◽  
Water Soluble ◽  
Formaldehyde Resin ◽  
Electron Microscope Autoradiography ◽  
Resorcinol Formaldehyde ◽  
Major Disadvantage ◽  
Cell Organization

The extraction of lipids from tissues during fixation and embedding for electron microscopy is widely recognized as a source of possible artifact, especially at the membrane level of cell organization. Lipid extraction is also a major disadvantage in electron microscope autoradiography of radioactive lipids, as in studies of the uptake of radioactive fatty acids by intestinal slices. Retention of lipids by fixation with osmium tetroxide is generally limited to glycolipids, phospholipids and highly unsaturated neutral lipids. Saturated neutral lipids and sterols tend to be easily extracted by organic dehydrating reagents prior to embedding. Retention of the more saturated lipids in embedded tissue might be achieved by developing new cross-linking reagents, by the use of highly water soluble embedding materials or by working at very low temperatures.

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