Alternative molecularly imprinted polymeric membranes from a tetrapeptide residue consisting of D- or L-amino acids

1997 ◽  
Vol 18 (9) ◽  
pp. 761-767 ◽  
Author(s):  
Masakazu Yoshikawa ◽  
Jun-ichiro Izumi ◽  
Toshio Kitao ◽  
Shunji Sakamoto
Keyword(s):  
Amino Acids ◽  
Polymeric Membranes ◽  
Molecularly Imprinted

Molecularly Imprinted Polymeric Membranes Containing DIDE Derivatives for Optical Resolution of Amino Acids†

1996 ◽  
Vol 29 (25) ◽  
pp. 8197-8203 ◽  
Author(s):  
Masakazu Yoshikawa ◽  
Jun-ichiro Izumi ◽  
Toshio Kitao ◽  
Shunji Sakamoto
Keyword(s):  
Amino Acids ◽  
Optical Resolution ◽  
Polymeric Membranes ◽  
Molecularly Imprinted

Molecularly imprinted polymeric membranes involving tetrapeptide EQKL derivatives as chiral-recognition sites toward amino acids

1998 ◽  
Vol 365 (1-3) ◽  
pp. 59-67 ◽  
Author(s):  
Masakazu Yoshikawa ◽  
Takashi Fujisawa ◽  
Jun-ichiro Izumi ◽  
Toshio Kitao ◽  
Shunji Sakamoto
Keyword(s):  
Amino Acids ◽  
Chiral Recognition ◽  
Polymeric Membranes ◽  
Molecularly Imprinted ◽  
Recognition Sites

Molecularly imprinted polymeric membranes for optical resolution

1995 ◽  
Vol 108 (1-2) ◽  
pp. 171-175 ◽  
Author(s):  
Masakazu Yoshikawa ◽  
Jun-ichiro Izumi ◽  
Toshio Kitao ◽  
Susumu Koya ◽  
Shunji Sakamoto
Keyword(s):  
Optical Resolution ◽  
Polymeric Membranes ◽  
Molecularly Imprinted

scholarly journals Monitoring of Irinotecan in Human Plasma: Sensitive Fluorescent Nanogels by Molecular Imprinting

2019 ◽  
Author(s):  
Martina Tommasini ◽  
Elena Pellizzoni ◽  
Valentina Iacuzzi ◽  
Elena Marangon ◽  
Paola Posocco ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fluorescence Quenching ◽  
Human Plasma ◽  
Molecular Imprinting ◽  
Plasma Sample ◽  
Direct Detection ◽  
Fluorescent Nanoparticles ◽  
High Dilution ◽  
Molecularly Imprinted

A series of fluorescent molecularly imprinted nanogels to detect irinotecan (CPT11) were prepared and characterized. A set of amino acids and napthalimide polymerisable derivatives allowed to obtain polymers as soluble fluorescent nanoparticles by high dilution imprinted synthesis. The direct detection of irinotecan in human plasma was obtained by fluorescence quenching of the naphtalimide-based imprinted materials. The plasma sample treated with acetonitrile allowed the detection of irinotecan in the 10nM – 30μM range. The LOD was 9.4 nM, with within-run variability 10% and day to day variability 13%.<br>

scholarly journals Molecularly imprinted polymers in biological applications

BioTechniques ◽  
2020 ◽  
Vol 69 (6) ◽  
pp. 406-419
Author(s):  
Zahra El-Schich ◽  
Yuecheng Zhang ◽  
Marek Feith ◽  
Sarah Beyer ◽  
Louise Sternbæk ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecularly Imprinted Polymers ◽  
Low Cost ◽  
Cancer Diagnostics ◽  
Biological Applications ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Recognition Elements ◽  
Synthesis Procedure

Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors, in vivo applications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.

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