Application of Multivariate and Spectroscopic Techniques for Investigation of the Interactions between Polyelectrolyte Layers in Layer‐by‐Layer Assembled pH‐Sensitive Nanocapsules

2021 ◽  
pp. 2100107
Author(s):  
Anita Mashoofnia ◽  
Zahra Mohamadnia ◽  
Mohsen Kompany‐Zareh
Keyword(s):  
Ph Sensitive ◽  
Spectroscopic Techniques ◽  
Layer By Layer

scholarly journals Capacitive Field-effect (bio-)chemical Sensors Based on Nanocrystalline Diamond Films

2009 ◽  
Vol 1203 ◽  
Author(s):  
Matthias Bäcker ◽  
Arshak Poghossian ◽  
Maryam H. Abouzar ◽  
Sylvia Wenmackers ◽  
Stoffel D. Janssens ◽  
...  
Keyword(s):  
Thin Films ◽  
Field Effect ◽  
High Sensitivity ◽  
Ph Sensitive ◽  
Nanocrystalline Diamond ◽  
Penicillin G ◽  
Layer By Layer ◽  
Label Free ◽  
High Coverage ◽  
Layer Adsorption

AbstractCapacitive field-effect electrolyte-diamond-insulator-semiconductor (EDIS) structures with O-terminated nanocrystalline diamond (NCD) as sensitive gate material have been realized and investigated for the detection of pH, penicillin concentration, and layer-by-layer adsorption of polyelectrolytes. The surface oxidizing procedure of NCD thin films as well as the seeding and NCD growth process on a Si-SiO2 substrate have been improved to provide high pH-sensitive, non-porous thin films without damage of the underlying SiO2 layer and with a high coverage of O-terminated sites. The NCD surface topography, roughness, and coverage of the surface groups have been characterized by SEM, AFM and XPS methods. The EDIS sensors with O-terminated NCD film treated in oxidizing boiling mixture for 45 min show a pH sensitivity of about 50 mV/pH. The pH-sensitive properties of the NCD have been used to develop an EDIS-based penicillin biosensor with high sensitivity (65-70 mV/decade in the concentration range of 0.25-2.5 mM penicillin G) and low detection limit (5 μM). The results of label-free electrical detection of layer-by-layer adsorption of charged polyelectrolytes are presented, too.

Ultrathin Layer-by-Layer Hydrogels with Incorporated Gold Nanorods as pH-Sensitive Optical Materials

2008 ◽  
Vol 20 (24) ◽  
pp. 7474-7485 ◽  
Author(s):  
Veronika Kozlovskaya ◽  
Eugenia Kharlampieva ◽  
Bishnu P. Khanal ◽  
Pramit Manna ◽  
Eugene R. Zubarev ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Optical Materials ◽  
Ph Sensitive ◽  
Layer By Layer ◽  
Ultrathin Layer

scholarly journals Layer-by-layer pH-sensitive nanoparticles for drug delivery and controlled release with improved therapeutic efficacy in vivo

Drug Delivery ◽  
2020 ◽  
Vol 27 (1) ◽  
pp. 180-190 ◽  
Author(s):  
Wanfu Men ◽  
Peiyao Zhu ◽  
Siyuan Dong ◽  
Wenke Liu ◽  
Kun Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Therapeutic Efficacy ◽  
Ph Sensitive ◽  
Layer By Layer

The pH-sensitive switchable behavior based on the layer-by-layer films of hemoglobin and Ag nanoparticles

2011 ◽  
Vol 13 (12) ◽  
pp. 1502-1505 ◽  
Author(s):  
Chunmei Yu ◽  
Wanyu Ji ◽  
Lili Gou ◽  
Ning Bao ◽  
Haiying Gu
Keyword(s):  
Ag Nanoparticles ◽  
Ph Sensitive ◽  
Layer By Layer ◽  
Behavior Based

Fabrication of Polymer Light Emitting Diodes by Layer-by-Layer Complexation Technique

1997 ◽  
Vol 488 ◽  
Author(s):  
Jaehyun Kim ◽  
Kethinni G. Chittibabu ◽  
Mario J. Cazeca ◽  
Woohong Kim ◽  
Jayant Kumar ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Multilayer Film ◽  
Multilayer Films ◽  
Spectroscopic Techniques ◽  
Layer By Layer ◽  
Light Emitting ◽  
Electroluminescence Brightness ◽  
Polymer Light Emitting Diodes ◽  
Uv Visible ◽  
Hydrolysis Of

AbstractMultilayer films were fabricated employing a new layer-by-layer complexation technique by alternatively dipping substrates in solutions of macromolecular ligands and Eu3+ ions. A luminescent poly[2-(3-thienyl)ethanol hydroxycarbonyl-methyl urethane] (H-PURET) was prepared by hydrolysis of thiophene polymer, poly[2-(3-thienyl)ethanol butoxycarbonyl-methyl urethane] (PURET), which was developed in our laboratory. H-PURET was used as macromolecular ligands. The multilayer deposition was monitored using UV-visible spectroscopy. As the number of bilayers increases, the absorption due to the polymer increases. The multilayer films were characterized by infrared and fluorescence spectroscopic techniques. Electroluminescence brightness easily obtained from the multilayer film of conjugated polymer-Eu3+ complex was measured to be about 40nW.

scholarly journals pH-Triggered release from surface-modified poly(lactic-co-glycolic acid) nanoparticles

2015 ◽  
Vol 6 ◽  
pp. 2504-2512 ◽  
Author(s):  
Manuel Häuser ◽  
Klaus Langer ◽  
Monika Schönhoff
Keyword(s):  
Self Assembly ◽  
Glycolic Acid ◽  
Ph Value ◽  
Particle System ◽  
Plga Nanoparticles ◽  
Ph Sensitive ◽  
Layer By Layer ◽  
Triggered Release ◽  
Layer System ◽  
H Nmr

Nanoparticles (NP) of poly(lactic-co-glycolic acid) (PLGA) represent a promising biodegradable drug delivery system. We suggest here a two-step release system of PLGA nanoparticles with a pH-tunable polymeric shell, providing an initial pH-triggered step, releasing a membrane-toxic cationic compound. PLGA nanoparticles are coated by polyelectrolytes using the layer-by-layer self-assembly technique, employing poly(acrylic acid) (PAA) as a pH-sensitive component and poly(diallyldimethylammonium chloride) (PDADMAC) as the releasable polycation. The pH during multilayer deposition plays a major role and influences the titration curve of the layer system. The pH-tunability of PAA is intensively investigated with regard to the pH region, in which the particle system becomes uncharged. The isoelectric point can be shifted by employing suitable deposition pH values. The release is investigated by quantitative 1H NMR, yielding a pH-dependent release curve. A release of PDADMAC is initiated by a decrease of the pH value. The released amount of polymer, as quantified by 1H NMR analysis, clearly depends on the pH value and thus on the state of deprotonation of the pH-sensitive PAA layer. Subsequent incubation of the nanoparticles with high concentrations of sodium chloride shows no further release and thus demonstrates the pH-driven release to be quantitative.

Dual pH-sensitive layer-by-layer films containing amphoteric poly(diallylamine-co-maleic acid)

2013 ◽  
Vol 399 ◽  
pp. 26-32 ◽  
Author(s):  
Yu Tokuda ◽  
Toshihide Miyagishima ◽  
Koji Tomida ◽  
Baozhen Wang ◽  
Shigehiro Takahashi ◽  
...  
Keyword(s):  
Maleic Acid ◽  
Ph Sensitive ◽  
Layer By Layer ◽  
Sensitive Layer
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