Temperature and Redox‐Responsive Hydrogels Based on Nitroxide Radicals and Oligoethyleneglycol Methacrylate

2020 ◽  
Vol 221 (6) ◽  
pp. 1900550
Author(s):  
Miriam Khodeir ◽  
Sayed Antoun ◽  
Evelyne Ruymbeke ◽  
Jean‐François Gohy
Keyword(s):  
Nitroxide Radicals ◽  
Redox Responsive ◽  
Responsive Hydrogels

scholarly journals Application of Redox-Responsive Hydrogels Based on 2,2,6,6-Tetramethyl-1-Piperidinyloxy Methacrylate and Oligo(Ethyleneglycol) Methacrylate in Controlled Release and Catalysis

Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1307
Author(s):  
Miriam Khodeir ◽  
He Jia ◽  
Alexandru Vlad ◽  
Jean-François Gohy
Keyword(s):  
Polymer Networks ◽  
Primary Alcohols ◽  
Nitroxide Radicals ◽  
Triggered Release ◽  
Specific Chemical ◽  
Co Catalyst ◽  
Redox Responsive ◽  
Responsive Hydrogels ◽  
Glycol Methyl Ether ◽  
Stable Nitroxide

Hydrogels have reached momentum due to their potential application in a variety of fields including their ability to deliver active molecules upon application of a specific chemical or physical stimulus and to act as easily recyclable catalysts in a green chemistry approach. In this paper, we demonstrate that the same redox-responsive hydrogels based on polymer networks containing 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) stable nitroxide radicals and oligoethylene glycol methyl ether methacrylate (OEGMA) can be successfully used either for the electrochemically triggered release of aspirin or as catalysts for the oxidation of primary alcohols into aldehydes. For the first application, we take the opportunity of the positive charges present on the oxoammonium groups of oxidized TEMPO to encapsulate negatively charged aspirin molecules. The further electrochemical reduction of oxoammonium groups into nitroxide radicals triggers the release of aspirin molecules. For the second application, our hydrogels are swelled with benzylic alcohol and tert-butyl nitrite as co-catalyst and the temperature is raised to 50 °C to start the oxidation reaction. Interestingly enough, benzaldehyde is not miscible with our hydrogels and phase-separate on top of them allowing the easy recovery of the reaction product and the recyclability of the hydrogel catalyst.

Metal Nanoparticle Foundry with Redox Responsive Hydrogels

2018 ◽  
Vol 219 (22) ◽  
pp. 1800223 ◽  
Author(s):  
Xueling Feng ◽  
Mark A. Hempenius ◽  
Gyula J. Vancso
Keyword(s):  
Metal Nanoparticle ◽  
Redox Responsive ◽  
Responsive Hydrogels

Double‐crosslinked reversible redox‐responsive hydrogels based on disulfide–thiol interchange

2019 ◽  
Vol 57 (24) ◽  
pp. 2590-2601 ◽  
Author(s):  
Yunjiao Che ◽  
Stefan Zschoche ◽  
Franziska Obst ◽  
Dietmar Appelhans ◽  
Brigitte Voit
Keyword(s):  
Reversible Redox ◽  
Redox Responsive ◽  
Responsive Hydrogels

Best of both worlds: Diels–Alder chemistry towards fabrication of redox-responsive degradable hydrogels for protein release

RSC Advances ◽  
2016 ◽  
Vol 6 (78) ◽  
pp. 74757-74764 ◽  
Author(s):  
Ismail Altinbasak ◽  
Rana Sanyal ◽  
Amitav Sanyal
Keyword(s):  
Ethylene Glycol ◽  
Alder Reaction ◽  
Diels Alder ◽  
Protein Release ◽  
Poly Ethylene Glycol ◽  
Diels Alder Reaction ◽  
Redox Responsive ◽  
Poly Ethylene ◽  
Responsive Hydrogels

Poly(ethylene glycol)-based redox-responsive hydrogels have been preparedviathe Diels–Alder reaction between a furan-containing hydrophilic copolymer and a disulfide-containing bis-maleimide based crosslinker.

Facile fabrication of thermo/redox responsive hydrogels based on a dual crosslinked matrix for a smart on–off switch

Soft Matter ◽  
2018 ◽  
Vol 14 (21) ◽  
pp. 4327-4334 ◽  
Author(s):  
Na Sun ◽  
Panpan Sun ◽  
Aoli Wu ◽  
Xuanxuan Qiao ◽  
Fei Lu ◽  
...  
Keyword(s):  
Chemical Crosslinking ◽  
Redox Responsive ◽  
Facile Fabrication ◽  
Responsive Hydrogels ◽  
Physical Crosslinking ◽  
Polyelectrolyte Hydrogel

A thermo- and redox-responsive polyelectrolyte hydrogel was facilely constructed based on a primary chemical crosslinking and a secondary physical crosslinking.

Enzyme-mediated preparation of hydrogels composed of poly(ethylene glycol) and gelatin as cell culture platforms

RSC Advances ◽  
2015 ◽  
Vol 5 (4) ◽  
pp. 3070-3073 ◽  
Author(s):  
Kousuke Moriyama ◽  
Rie Wakabayashi ◽  
Masahiro Goto ◽  
Noriho Kamiya
Keyword(s):  
Cell Culture ◽  
Horseradish Peroxidase ◽  
Ethylene Glycol ◽  
Cell Sheet ◽  
Viable Cell ◽  
Poly Ethylene Glycol ◽  
Redox Responsive ◽  
Poly Ethylene ◽  
Responsive Hydrogels

Horseradish peroxidase-mediated preparation of redox-responsive hydrogels composed of thiolated poly(ethylene glycol) and gelatin allowed the proliferation of cells on the gel and the harvest as a viable cell sheet.

Sign in / Sign up

Export Citation Format

Share Document