Dual UV- and pH-Responsive Supramolecular Vesicles Mediated by Host-Guest Interactions for Drug Controlled Release

2016 ◽  
Vol 217 (17) ◽  
pp. 1934-1940 ◽  
Author(s):  
Xiaojin Zhang ◽  
Renxi Zhuo
Keyword(s):  
Controlled Release ◽  
Ph Responsive ◽  
Drug Controlled Release

scholarly journals Aqueous-based electrospun P(NIPAAm-co-AAc)/RSF medicated fibrous mats for dual temperature- and pH-responsive drug controlled release

RSC Advances ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 323-331 ◽  
Author(s):  
Juan Li ◽  
Jingxin Zhu ◽  
Lan Jia ◽  
Yanlong Ma ◽  
Haijuan Wu
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Ph Responsive ◽  
Drug Controlled Release

This paper presents a green friendly method for preparing dual temperature- and pH-responsive electrospun P(NIPAAm-co-AAc)/RSF fibrous mats for drug release.

pH-responsive electrospun nanofibrous membrane for drug controlled release

2013 ◽  
Vol 172 (1) ◽  
pp. e71 ◽  
Author(s):  
Wei Li ◽  
Yang Shi ◽  
Tian Luo ◽  
Siyu Liu ◽  
Li Liu
Keyword(s):  
Controlled Release ◽  
Nanofibrous Membrane ◽  
Ph Responsive ◽  
Drug Controlled Release

P(EO-co-LLA) functionalized Fe3O4@mSiO2 nanocomposites for thermo/pH responsive drug controlled release and hyperthermia

2014 ◽  
Vol 43 (48) ◽  
pp. 18056-18065 ◽  
Author(s):  
Wei Guo ◽  
Chunyu Yang ◽  
Huiming Lin ◽  
Fengyu Qu
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Ph Responsive ◽  
Drug Controlled Release ◽  
Nanoparticle Core

The Fe3O4@mSiO2 nanocarrier that consisted of a magnetic Fe3O4 nanoparticle core and a mesoporous silica (mSiO2) shell was synthesized.

scholarly journals pH-Responsive Micelles Assembled by Three-Armed Degradable Block Copolymers with a Cholic Acid Core for Drug Controlled-Release

Polymers ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 511 ◽  
Author(s):  
Jingjie Feng ◽  
Weiqiu Wen ◽  
Yong-Guang Jia ◽  
Sa Liu ◽  
and Jianwei Guo
Keyword(s):  
Controlled Release ◽  
Block Copolymers ◽  
Cholic Acid ◽  
Drug Loading ◽  
Ph Responsive ◽  
Triggered Release ◽  
Drug Controlled Release ◽  
Release Studies ◽  
Good Biocompatibility ◽  
Poly Ethylene

One of the most famous anticancer drugs, paclitaxel (PTX), has often been used in drug controlled-release studies. The polymers derived from bio-compound bile acids and degradable poly(ε-caprolactone) (PCL) form a reservoir and have been used as a drug delivery system with great advantages. Herein, we grafted poly(N,N-diethylaminoethyl methacrylate) and poly(poly(ethylene glycol) methyl ether methacrylate) into the bile acid-derived three-armed macroinitiator CA-(PCL)3, resulting in the amphiphilic block copolymers CA-(PCL-b-PDEAEMA-b-PPEGMA)3. These pH-responsive three-armed block copolymers self-assembled into micelles in aqueous solution and PTX was encapsulated into the micellar core to form PTX-loaded micelles with a drug loading of 29.92 wt %. The micelles were stable in PBS at pH 7.4 and showed a pH-triggered release behavior of PTX under acidic environments, in which 55% of PTX was released at pH 5.0 in 80 h. These cholic acid-based functionalized three-armed block polymers present good biocompatibility, showing great potential for drug controlled-release.

Antibiotic-anionic Clay Matrix Used for Drug Controlled Release

2018 ◽  
Vol 69 (2) ◽  
pp. 321-323
Author(s):  
Georgeta Zegan ◽  
Elena Mihaela Carausu ◽  
Loredana Golovcencu ◽  
Alina Sodor Botezatu ◽  
Eduard Radu Cernei ◽  
...  
Keyword(s):  
Controlled Release ◽  
Layered Double Hydroxides ◽  
Bioactive Molecules ◽  
Drug Controlled Release ◽  
Anionic Clays ◽  
Anionic Clay ◽  
Toxicological Studies ◽  
High Efficient ◽  
Clay Matrix ◽  
Double Hydroxides

Anionic clay matrix acting as drug controlled release system have shown in last years a great potential for delivery of bioactive molecules and chemical therapeutics. This organic-inorganic nanohybrid system is high efficient offering an excellent protection of intercalated compounds from degradation. Compared to other nanoparticles used in medical area, anionic clays type layered double hydroxides have found to be biocompatible according to toxicological studies. Ampicillin containing MgAlLDHs and ZnAlLDH samples have been prepared following two routes: anion-exchange procedure and reconstruction from calcined layered double hydroxides. Solid samples have been characterized by FTIR and SEM-EDX highlighting the alteration of pristine LDHs structure when the antibiotic is introduced in the interlayer gallery.

scholarly journals pH and redox dual-sensitive drug delivery system constructed based on fluorescent carbon dots

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2656-2663
Author(s):  
Boye Zhang ◽  
Qianqian Duan ◽  
Yi Li ◽  
Jianming Wang ◽  
Wendong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Ph Responsive ◽  
Charge Reversal ◽  
Fluorescent Carbon Dots

The system is pH-responsive and redox-controlled release. And the charge reversal and size transitions of the system can enhance the targeted ability. Moreover, the system can recognize the cancer cells by the fluorescence imaging.

Magnetic- and pH-responsive κ-carrageenan/chitosan complexes for controlled release of methotrexate anticancer drug

2017 ◽  
Vol 97 ◽  
pp. 209-217 ◽  
Author(s):  
Gholam Reza Mahdavinia ◽  
Amirabbas Mosallanezhad ◽  
Moslem Soleymani ◽  
Mohammad Sabzi
Keyword(s):  
Controlled Release ◽  
Anticancer Drug ◽  
Ph Responsive

Novel thermo- and pH-responsive hydroxypropyl cellulose- and poly (l-glutamic acid)-based microgels for oral insulin controlled release

2012 ◽  
Vol 89 (4) ◽  
pp. 1207-1214 ◽  
Author(s):  
Yunyan Bai ◽  
Zhe Zhang ◽  
Aiping Zhang ◽  
Li Chen ◽  
Chaoliang He ◽  
...  
Keyword(s):  
Controlled Release ◽  
Glutamic Acid ◽  
Hydroxypropyl Cellulose ◽  
Oral Insulin ◽  
Ph Responsive
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