Gelation Behavior of Bioabsorbable Hydrogels Consisting of Enantiomeric Mixtures of A-B-A Tri-block Copolymers of Polylactides (A) and Poly(ethylene glycol) (B)

2012 ◽  
Vol 213 (20) ◽  
pp. 2174-2180 ◽  
Author(s):  
Chan Woo Lee ◽  
Tomoyuki Manoshiro ◽  
Yu-I Hsu ◽  
Yoshiharu Kimura
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Gelation Behavior ◽  
Poly Ethylene

scholarly journals Structures and Applications of Thermoresponsive Hydrogels and Nanocomposite-Hydrogels Based on Copolymers with Poly (Ethylene Glycol) and Poly (Lactide-Co-Glycolide) Blocks

2019 ◽  
Vol 6 (4) ◽  
pp. 107 ◽  
Author(s):  
Tomoki Maeda
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Poly Lactic Acid ◽  
Poly Ethylene Glycol ◽  
Nanocomposite Hydrogels ◽  
Regeneration Medicine ◽  
Gelation Behavior ◽  
Thermoresponsive Hydrogels ◽  
Poly Ethylene

Thermoresponsive hydrogels showing biocompatibility and degradability have been under intense investigation for biomedical applications, especially hydrogels composed of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLGA) as first-line materials. Even though various aspects such as gelation behavior, degradation behavior, drug-release behavior, and composition effect have been studied for 20 years since the first report of these hydrogels, there are still many outputs on parameters affecting their gelation, structure, and application. In this review, the current trends of research on linear block copolymers composed of PEG and PLGA during the last 5 years (2014–2019) are summarized. In detail, this review stresses newly found parameters affecting thermoresponsive gelation, findings from structural analysis by simulation, small-angle neutron scattering (SANS), etc., progress in biomedical applications including drug delivery systems and regeneration medicine, and nanocomposites composed of block copolymers with PEG and PLGA and nanomaterials (laponite).

scholarly journals Intracellular Trafficking of Polyamidoamine–Poly(ethylene glycol) Block Copolymers in DNA Delivery

2011 ◽  
Vol 22 (8) ◽  
pp. 1519-1525 ◽  
Author(s):  
Daniel K. Bonner ◽  
Cheuk Leung ◽  
Jane Chen-Liang ◽  
Loice Chingozha ◽  
Robert Langer ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Intracellular Trafficking ◽  
Dna Delivery ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate)

Biomaterials ◽  
2004 ◽  
Vol 25 (2) ◽  
pp. 247-258 ◽  
Author(s):  
A.A. Deschamps ◽  
A.A. van Apeldoorn ◽  
H. Hayen ◽  
J.D. de Bruijn ◽  
U. Karst ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
In Vitro Degradation ◽  
Butylene Terephthalate ◽  
Poly Ethylene ◽  
Ether Ester

Micellar carriers based on block copolymers of poly(ε-caprolactone) and poly(ethylene glycol) for doxorubicin delivery

2004 ◽  
Vol 98 (3) ◽  
pp. 415-426 ◽  
Author(s):  
Xintao Shuai ◽  
Hua Ai ◽  
Norased Nasongkla ◽  
Saejeong Kim ◽  
Jinming Gao
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Doxorubicin Delivery ◽  
Poly Ethylene
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