Non‐Anticoagulant Heparin Prodrug Loaded Biodegradable and Injectable Thermoresponsive Hydrogels for Enhanced Anti‐Metastasis Therapy

2019 ◽  
Vol 19 (5) ◽  
pp. 1800409 ◽  
Author(s):  
Abegaz Tizazu Andrgie ◽  
Shewaye Lakew Mekuria ◽  
Kefyalew Dagnew Addisu ◽  
Balkew Zewge Hailemeskel ◽  
Wei‐Hsin Hsu ◽  
...  
Keyword(s):  
Thermoresponsive Hydrogels ◽  
Metastasis Therapy

scholarly journals MMP9-sensitive polymers mediate environmentally-responsive bivalirudin release and thrombin inhibition

2015 ◽  
Vol 3 (1) ◽  
pp. 41-45 ◽  
Author(s):  
D. S. Chu ◽  
D. L. Sellers ◽  
M. J. Bocek ◽  
A. E. Fischedick ◽  
P. J. Horner ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injuries ◽  
Peptide Delivery ◽  
Therapeutic Peptide ◽  
Thrombin Inhibition ◽  
Injured Tissue ◽  
Environmentally Responsive ◽  
Thermoresponsive Hydrogels

Enzymatically-responsive bivalirudin polymers loaded in thermoresponsive hydrogels mediate localized therapeutic peptide delivery in spinal cord injuries. These materials respond to upregulated remodelling enzymes to release therapeutic peptide into injured tissue.

LIM kinase-2 targeting as a possible anti-metastasis therapy

2004 ◽  
Vol 6 (3) ◽  
pp. 357-363 ◽  
Author(s):  
Eigo Suyama ◽  
Renu Wadhwa ◽  
Hiroaki Kawasaki ◽  
Tomoko Yaguchi ◽  
Sunil C. Kaul ◽  
...  
Keyword(s):  
Lim Kinase ◽  
Metastasis Therapy

Cell Protective, ABC Triblock Polymer-Based Thermoresponsive Hydrogels with ROS-Triggered Degradation and Drug Release

2014 ◽  
Vol 136 (42) ◽  
pp. 14896-14902 ◽  
Author(s):  
Mukesh K. Gupta ◽  
John R. Martin ◽  
Thomas A. Werfel ◽  
Tianwei Shen ◽  
Jonathan M. Page ◽  
...  
Keyword(s):  
Drug Release ◽  
Triblock Polymer ◽  
Thermoresponsive Hydrogels

Thermoresponsive hydrogels based on renewable resources

2019 ◽  
Vol 137 (28) ◽  
pp. 48861 ◽  
Author(s):  
Elif Isikci Koca ◽  
Gülnihal Bozdag ◽  
Gökhan Cayli ◽  
Dilek Kazan ◽  
Pinar Cakir Hatir
Keyword(s):  
Renewable Resources ◽  
Thermoresponsive Hydrogels
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