scholarly journals Determinants of outcome among patients with acute liver failure listed for liver transplantation in the United States

2016 ◽  
Vol 22 (4) ◽  
pp. 505-515 ◽  
Author(s):  
K. Rajender Reddy ◽  
Caitlyn Ellerbe ◽  
Michael Schilsky ◽  
R. Todd Stravitz ◽  
Robert J. Fontana ◽  
...  
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
The United States

Gender Differences in Acute Liver Failure in Patients Waitlisted for Liver Transplantation in the United States

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S475-S476
Author(s):  
Zahra Zia ◽  
Marwan Ghabril ◽  
Eric Orman ◽  
Naga Chalasani ◽  
Lauren Nephew
Keyword(s):  
United States ◽  
Gender Differences ◽  
Liver Transplantation ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
The United States

scholarly journals Liver transplantation for acute liver failure from drug induced liver injury in the United States

2004 ◽  
Vol 10 (8) ◽  
pp. 1018-1023 ◽  
Author(s):  
Mark W. Russo ◽  
Joseph A. Galanko ◽  
Roshan Shrestha ◽  
Michael W. Fried ◽  
Paul Watkins
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Liver Injury ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
The United States ◽  
Drug Induced ◽  
Drug Induced Liver Injury

scholarly journals Valproic Acid-Associated Acute Liver Failure in Children: Case Report and Analysis of Liver Transplantation Outcomes in the United States

2011 ◽  
Vol 158 (5) ◽  
pp. 802-807 ◽  
Author(s):  
Ayse L. Mindikoglu ◽  
Dale King ◽  
Laurence S. Magder ◽  
John A. Ozolek ◽  
George V. Mazariegos ◽  
...  
Keyword(s):  
United States ◽  
Valproic Acid ◽  
Liver Transplantation ◽  
Case Report ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
The United States ◽  
Transplantation Outcomes

Acute Liver Failure in the United States

2003 ◽  
Vol 139 (12) ◽  
pp. 1045 ◽  
Author(s):  
William M. Lee ◽  
Anne Larson ◽  
Robert Fontana ◽  
George Ostapowicz
Keyword(s):  
United States ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
The United States

scholarly journals Etiology and Outcome of Acute Liver Failure: Experience from a Liver Transplantation Centre in Montreal

2002 ◽  
Vol 16 (10) ◽  
pp. 672-676 ◽  
Author(s):  
Geneviève Tessier ◽  
Edith Villeneuve ◽  
Jean-Pierre Villeneuve
Keyword(s):  
Liver Transplantation ◽  
Liver Injury ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Rapid Development ◽  
Significant Proportion ◽  
Rare Condition ◽  
Unknown Origin ◽  
The United States ◽  
Drug Induced

BACKGROUND: Acute liver failure is a rare condition in which massive liver injury is associated with the rapid development of hepatic encephalopathy. Although viral hepatitis and drug-induced liver injury are the most common causes, no specific etiology is found in a substantial proportion of cases reported from Europe and the United States.AIM: To determine the etiology and outcome of patients with acute liver failure in the authors’ institution.PATIENTS AND METHODS: The charts of 81 consecutive patients admitted to Saint-Luc between 1991 and 1999 were reviewed.RESULTS: The etiology was viral in 27 cases (33.2%), toxic or drug-induced in 22 (27.2%), of unknown origin in 22 (27.2%) and due to various causes in 10 (12.3%) (autoimmune, vascular, cancer). Of the 81 patients, 16% survived without liver transplantation, and 84% died or underwent liver transplantation. Survival without liver transplantation differed according to the mode of presentation: the survival rate was 27% in patients with hyperacute liver failure, 7% in those with acute liver failure and 0% in those with subacute liver failure. Among the 38 patients who underwent liver transplantation, survival one year after transplantation was 71%. In the 30 patients who died without liver transplantation, the main causes of death were cerebral edema and sepsis.CONCLUSIONS: Acute liver failure is associated with a high mortality, and liver transplantation is the treatment of choice. In a significant proportion of cases, the etiology remains undetermined and is probably related to yet unidentified hepatotropic viruses.

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