scholarly journals Anemia is not predictive of sustained virological response in liver transplant recipients with hepatitis C virus who are treated with pegylated interferon and ribavirin

2011 ◽  
Vol 17 (11) ◽  
pp. 1318-1327 ◽  
Author(s):  
Michela Giusto ◽  
Maria Rodriguez ◽  
Laia Navarro ◽  
Angel Rubin ◽  
Victoria Aguilera ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Transplant ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Pegylated Interferon ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

Long-term maintenance of sustained virological response in liver transplant recipients treated for recurrent hepatitis C

2014 ◽  
Vol 46 (5) ◽  
pp. 440-445 ◽  
Author(s):  
Francesca Romana Ponziani ◽  
Raffaella Viganò ◽  
Rosa Maria Iemmolo ◽  
Maria Francesca Donato ◽  
Maria Rendina ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Liver Transplant ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Transplant Recipients ◽  
Recurrent Hepatitis ◽  
Recurrent Hepatitis C ◽  
Liver Transplant Recipients ◽  
Term Maintenance

scholarly journals PEGYLATED INTERFERON AND RIBAVIRIN FOR TREATMENT OF RECURRENT HEPATITIS C AFTER LIVER TRANSPLANTATION: a single-liver transplant center experience in Brazil

2015 ◽  
Vol 52 (3) ◽  
pp. 216-221
Author(s):  
José Huygens Parente GARCIA ◽  
Antônio Haroldo de ARAÚJO FILHO ◽  
Lucia Libanez Bessa Campelo BRAGA ◽  
Cyntia Ferreira Gomes VIANA ◽  
Tarciso Daniel Santos ROCHA ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Transplant ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Response Rate ◽  
Pegylated Interferon ◽  
Antiviral Drugs ◽  
Recipient Age

BackgroundTreatment of hepatitis C virus infection in post-transplantation patients is a challenge due to poor tolerance and low success rates.ObjectiveTo determine the response rate to pegylated interferon and ribavirin in post-liver transplant patients with hepatitis C recurrence.MethodsBetween 18 May 2002 and 18 December 2011, 601 patients underwent liver transplantation at our service (Hospital Universitário Walter Cantídio, University of Ceará), 176 (29.2%) of whom were hepatitis C virus positive. Forty received antiviral therapy and were included in this cohort study. Twenty-eight (70%) completed the treatment protocol, which consisted of pegylated interferon and ribavirin for 48 weeks.ResultsThe sustained virological response rate was 55% according to intention-to-treat analysis. Recipient age and exposure to antiviral drugs prior to liver transplantation were associated with sustained virological response in the multivariate analysis. Patients were followed for 57 months on the average. Survival at 1 and 5 years was 100% in responders, versus 100% and 78%, respectively, in non-responders.ConclusionSustained virological response rates were satisfactory in our series of liver transplantation patients, and decreased with increasing recipient age. Non-exposure to antiviral drugs prior to liver transplantation was positively associated with sustained virological response. The overall survival of responders and non-responders was similar.

Achieving Sustained Virological Response in Liver Transplant Recipients With Hepatitis C Decreases Risk of Decline in Renal Function

2018 ◽  
Vol 24 (8) ◽  
pp. 1040-1049 ◽  
Author(s):  
Sanjaya K. Satapathy ◽  
Kiran Joglekar ◽  
Miklos Z. Molnar ◽  
Bilal Ali ◽  
Humberto C. Gonzalez ◽  
...  
Keyword(s):  
Renal Function ◽  
Hepatitis C ◽  
Liver Transplant ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Transplant Recipients ◽  
Liver Transplant Recipients
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