scholarly journals Stereological evaluation of liver volume in living donor liver transplantation using MDCT via the cavalieri method

2007 ◽  
Vol 13 (5) ◽  
pp. 693-698 ◽  
Author(s):  
Cihan Duran ◽  
Bulent Aydinli ◽  
Yaman Tokat ◽  
Yildiray Yuzer ◽  
Mecit Kantarci ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Liver Transplantation

Assessment of Graft Selection Criteria in Living-Donor Liver Transplantation: The Jikei Experience

2015 ◽  
Vol 100 (7-8) ◽  
pp. 1229-1232 ◽  
Author(s):  
Hiroaki Shiba ◽  
Shigeki Wakiyama ◽  
Yasuro Futagawa ◽  
Tomonori Iida ◽  
Michinori Matsumoto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Good Condition ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Liver Donation ◽  
Living Liver Donation ◽  
Graft Selection

In living-donor liver transplantation, graft selection is especially important for the safety of the live donor and an acceptable outcome for the recipient. The essential medical requirements for living liver donation at Jikei University Hospital are as follows: an adult aged 65 years or younger, in good general condition, with partial liver volume of more than 35% of the standard liver volume (SLV) for the recipient, and without severe liver steatosis. Based on our criteria, we performed 13 living-donor liver transplantations between 2007 and 2013, including 1 retransplantation. Three cases were outside our standard donor criteria, including age (18 and 66 years) and 33% graft volume (GV) to SLV ratio for the recipient on preoperative volumetry using computed tomography. In 2 cases, the actual GV to SLV ratio at transplantation was less than 35%. Median postoperative hospital stay was 11 days for the donors, and 29 days for the recipients. All donors returned to their preoperative status, and all recipients were discharged in good condition. Our medical requirements for living liver donation seem to be acceptable because of the good outcome.

A new formula for calculating standard liver volume for living donor liver transplantation without using body weight

2015 ◽  
Vol 63 (4) ◽  
pp. 848-854 ◽  
Author(s):  
Takashi Kokudo ◽  
Kiyoshi Hasegawa ◽  
Emilie Uldry ◽  
Yutaka Matsuyama ◽  
Junichi Kaneko ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Body Weight ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Standard Liver Volume ◽  
New Formula

scholarly journals How Far Does Residual Liver Volume Affect Portal Pressure Gradient During Donor Hepatectomy in Living Donor Liver Transplantation

2019 ◽  
Vol 87 (March) ◽  
pp. 41-44
Author(s):  
AHMED H. KHALIL, M.D., M.R.C.S.; MOHAMMED KHATTAB, M.Sc. ◽  
KAREEM HOSNY, M.D. MOSTAFA EL-SHAZLY, M.D. ◽  
AYMAN SALAH ELDIN, M.D. ADEL HOSNY, M.D.
Keyword(s):  
Liver Transplantation ◽  
Pressure Gradient ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Portal Pressure ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Hepatectomy ◽  
Donor Liver Transplantation

scholarly journals DALU-Net: Automated Liver Segmentation and Volumetry for Liver Transplantation in Abdominal Computed Tomography Volumes

2021 ◽  
Author(s):  
Jin Gyo Jeong ◽  
Sangtae Choi ◽  
Young Jae Kim ◽  
Won-Suk Lee ◽  
Kwang Gi Kim
Keyword(s):  
Liver Transplantation ◽  
Network Architecture ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Volume Data ◽  
Liver Segmentation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Ct Volume

Abstract Liver transplantation is performed in patients with liver disease, using the liver of a braindead or living donor. In living-donor liver transplantation, the safety of the donor is critical. In addition, the amount that can be resected from the living donor is limited. It is important that accurately measuring the liver volume to avoid graft size mismatch. In this paper, we designed a deep attention convolutional long short-term memory (CLSTM) network architecture for liver segmentation that combines an attention mechanism, deep supervision, and CLSTM. The proposed model can focus on the liver in abdominal CT volume data and can learn inter-slice using CLSTM. Our framework was trained using 133 training cases, 29 validation cases, and 29 test cases of liver donors. We compared livers and volumes manually labeled by a liver transplant surgeon and those obtained by automatic segmentation of livers and volumes. We further evaluated the segmentation and volumetry of the left lobe, right lobe, and caudate lobe, according to the anatomical structure of the liver. Our approach significantly outperformed the 3D U-Net in terms of accuracy. Our approach can be used as an aid in estimating liver volume from CT volume data for living-donor liver transplantation.

Comparison between manual and automated CT liver volumetry in assessment of the liver volume in living donor liver transplantation

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Omina Ahmed Kamal ◽  
Enas Ahmed Azab ◽  
Ahmed Abdelsamie Mahmoud ◽  
Emad Hamid Abdeldayem ◽  
Eslam Mahmoud Taha
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Statistical Significance ◽  
Liver Volume ◽  
Reference Standard ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Liver Volumetry ◽  
The Difference

Abstract Aim of the work To evaluate the effectiveness and advantages of automated CT volumetry in the assessment of liver volume in living donor liver transplantation and to compare this technique and its results with those calculated from manual volumetry. Materials and Methods This comparative study was conducted on dynamic contrast enhanced hepatic CT scans of 21 potential living liver donors. All potential donors underwent 1st step laboratory investigations to enter the 2nd step investigations for living donor liver transplantation operation. Automated liver volumetry was developed using the Myrian® XP-Liver software. To establish reference standard liver volumes, a radiologist manually traced the contour of the liver on each CT slice. We compared the results obtained with automated with those obtained with the reference standard for this study, manual volumetry. Results The study showed that automated CT liver volumetry achieved excellent agreement with manual volumetry without statistical significance. The average processing times for automated volumetry was 3.09 ± 0.44 min/case, whereas those for manual volumetry were 16.23 ± 0.81 min/case, the difference was statistically significant (p < 0.05). Conclusion Automated CT liver volumetry performed using the Myrian® XP-Liver software can accurately predict the preoperative liver volume and provide acceptable measurements comparable to the gold standard manual volumetry.

scholarly journals Portal flow modulation in living donor liver transplantation: review with a focus on splenectomy

Surgery Today ◽  
2019 ◽  
Vol 50 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Tomoharu Yoshizumi ◽  
Masaki Mori
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Current Knowledge ◽  
Liver Volume ◽  
Weight Ratio ◽  
Portal Flow ◽  
Donor Liver ◽  
Flow Modulation ◽  
Donor Liver Transplantation

Abstract Small-for-size graft (SFSG) syndrome after living donor liver transplantation (LDLT) is the dysfunction of a small graft, characterized by coagulopathy, cholestasis, ascites, and encephalopathy. It is a serious complication of LDLT and usually triggered by excessive portal flow transmitted to the allograft in the postperfusion setting, resulting in sinusoidal congestion and hemorrhage. Portal overflow injures the liver directly through nutrient excess, endothelial activation, and sinusoidal shear stress, and indirectly through arterial vasoconstriction. These conditions may be attenuated with portal flow modulation. Attempts have been made to control excessive portal flow to the SFSG, including simultaneous splenectomy, splenic artery ligation, hemi-portocaval shunt, and pharmacological manipulation, with positive outcomes. Currently, a donor liver is considered a SFSG when the graft-to-recipient weight ratio is less than 0.8 or the ratio of the graft volume to the standard liver volume is less than 40%. A strategy for transplanting SFSG safely into recipients and avoiding extensive surgery in the living donor could effectively address the donor shortage. We review the literature and assess our current knowledge of and strategies for portal flow modulation in LDLT.

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