Effect of Artesunate Combined With Fractional CO 2 Laser on the Hypertrophic Scar in a Rabbit Model

2021 ◽  
Author(s):  
Jinxia Zhang ◽  
Zhikuan Xia ◽  
Shuanglin Zhou ◽  
Wanting Luo ◽  
Zhuoying Peng ◽  
...  
Keyword(s):  
Hypertrophic Scar ◽  
Rabbit Model

Topical Application of a Silicone Gel Sheet with Verapamil Microparticles in a Rabbit Model of Hypertrophic Scar

2016 ◽  
Vol 137 (1) ◽  
pp. 144-151 ◽  
Author(s):  
Eun Young Rha ◽  
Yun Ho Kim ◽  
Tae-Jung Kim ◽  
Gyeol Yoo ◽  
Jong Won Rhie ◽  
...  
Keyword(s):  
Topical Application ◽  
Hypertrophic Scar ◽  
Rabbit Model ◽  
Silicone Gel ◽  
Silicone Gel Sheet

scholarly journals Extracellular Vesicles Derived From Human Adipose-Derived Stem Cell Prevent the Formation of Hypertrophic Scar in a Rabbit Model

2020 ◽  
Vol 84 (5) ◽  
pp. 602-607 ◽  
Author(s):  
Yuan-zheng Zhu ◽  
Xuan Hu ◽  
Jing Zhang ◽  
Zhao-hui Wang ◽  
Shu Wu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Extracellular Vesicles ◽  
Hypertrophic Scar ◽  
Rabbit Model ◽  
Adipose Derived Stem Cell

scholarly journals The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model

2020 ◽  
Vol 26 ◽  
Author(s):  
Shu Guo ◽  
Qiang Sun ◽  
Er-te Yu ◽  
You Zhou ◽  
Shuang Tong ◽  
...  
Keyword(s):  
Hypertrophic Scar ◽  
Postoperative Radiotherapy ◽  
Rabbit Model

Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model

2015 ◽  
Vol 750 ◽  
pp. 151-159 ◽  
Author(s):  
Kwan Chul Tark ◽  
Dong Won Lee ◽  
Dae Hyun Lew ◽  
Eun Hye Kang ◽  
Hyun Roh ◽  
...  
Keyword(s):  
Hypertrophic Scar ◽  
Rabbit Model ◽  
Ginsenoside Rb1

Fibroblasts During Hypertrophic Scar Formation and Resolution

1973 ◽  
Vol 31 ◽  
pp. 428-429
Author(s):  
C. W. Kischer
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Cell Proliferation ◽  
Fine Structure ◽  
Metabolic Activity ◽  
Hypertrophic Scar ◽  
Normal Skin ◽  
Ground Substance ◽  
Hypertrophic Scars ◽  
Scanning Electron

The morphology of the fibroblasts changes markedly as the healing period from burn wounds progresses, through development of the hypertrophic scar, to resolution of the scar by a self-limiting process of maturation or therapeutic resolution. In addition, hypertrophic scars contain an increased cell proliferation largely made up of fibroblasts. This tremendous population of fibroblasts seems congruous with the abundance of collagen and ground substance. The fine structure of these cells should reflect some aspects of the metabolic activity necessary for production of the scar, and might presage the stage of maturation.A comparison of the fine structure of the fibroblasts from normal skin, different scar types, and granulation tissue has been made by transmission (TEM) and scanning electron microscopy (SEM).

Dupuytren's Contracture and Microvessels

1981 ◽  
Vol 39 ◽  
pp. 470-471
Author(s):  
C. W. Klscher ◽  
D. Speer
Keyword(s):  
Hypertrophic Scar ◽  
Active Form ◽  
Scar Tissue ◽  
Vascular Supply ◽  
Fiber Bundles ◽  
Dupuytren’S Contracture ◽  
Palmar Fascia ◽  
Immune Disease ◽  
Dupuytren's Contracture ◽  
Longitudinal Fiber

Dupuytren's Contracture is a nodular proliferation of the longitudinal fiber bundles of palmar fascia with its attendant contraction. The factors attributed to its etiology have included trauma, diabetes, alcoholism, arthritis, and auto-immune disease. The tissue has been observed by electron microscopy and found to contain myofibroblasts.Dupuytren's Contracture constitutes a scar, and as such, excessive collagen can be observed, along with an active form of fibroblast.Previous studies of the hypertrophic scar have led us to propose that integral in the initiation and sustenance of scar tissue is a profusion of microvascular regeneration, much of which becomes and remains occluded producing a hypoxia which stimulates fibroblast synthesis. Thus, when considering a study of Dupuytren's Contracture, we predicted finding occluded microvessels at or near the fascial scarring focus.Three cases of Dupuytren's Contracture yielded similar specimens, which were fixed in Karnovskys fluid for 2 to 20 days. Upon removal of the contracture bands care was taken to include the contiguous fatty and areolar tissue which contain the vascular supply and to identify the junctional area between old and new fascia.

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