Large-area spectrally encoded confocal endomicroscopy of the human esophagus in vivo

2016 ◽  
Vol 49 (3) ◽  
pp. 233-239 ◽  
Author(s):  
Dongkyun Kang ◽  
Simon C. Schlachter ◽  
Robert W. Carruth ◽  
Minkyu Kim ◽  
Tao Wu ◽  
...  
Keyword(s):  
Large Area ◽  
Confocal Endomicroscopy ◽  
Spectrally Encoded ◽  
Human Esophagus

scholarly journals In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study

2017 ◽  
Vol 23 (18) ◽  
pp. 3338 ◽  
Author(s):  
Somashekar G Krishna ◽  
Rohan M Modi ◽  
Amrit K Kamboj ◽  
Benjamin J Swanson ◽  
Phil A Hart ◽  
...  
Keyword(s):  
Prospective Study ◽  
Ex Vivo ◽  
Cystic Lesions ◽  
Confocal Endomicroscopy ◽  
A Prospective Study

High-Resolution Confocal Endomicroscopy Probe System for In Vivo Diagnosis of Colorectal Neoplasia

2008 ◽  
Vol 135 (1) ◽  
pp. 295 ◽  
Author(s):  
Anna M. Buchner ◽  
Marwan S. Ghabril ◽  
Murli Krishna ◽  
Herbert C. Wolfsen ◽  
Michael B. Wallace
Keyword(s):  
High Resolution ◽  
Colorectal Neoplasia ◽  
Confocal Endomicroscopy ◽  
Probe System ◽  
In Vivo Diagnosis

852 In Vivo Imaging of Shedding Cells Induced By Enteral Bacteria Using Confocal Endomicroscopy in Humans

2009 ◽  
Vol 136 (5) ◽  
pp. A-130-A-131 ◽  
Author(s):  
Driffa Moussata ◽  
Martin Goetz ◽  
Alastair J. Watson ◽  
Arthur Hoffman ◽  
Jean-Christophe Saurin ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Confocal Endomicroscopy

628 In Vivo Imaging of Eosinophils With a Tethered Confocal Endomicroscopy Capsule

2015 ◽  
Vol 81 (5) ◽  
pp. AB158-AB159
Author(s):  
Nima Tabatabaei ◽  
Dongkyun Kang ◽  
Weina Lu ◽  
Tao Wu ◽  
Minkyu Kim ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Confocal Endomicroscopy

Esophageal manometry in the opossum.

1977 ◽  
Vol 233 (3) ◽  
pp. E152
Author(s):  
K Schulze ◽  
W J Dodds ◽  
J Christensen ◽  
J D Wood
Keyword(s):  
Animal Model ◽  
Lower Esophageal Sphincter ◽  
Esophageal Manometry ◽  
Lower Esophageal Sphincter Pressure ◽  
Upper Esophageal Sphincter ◽  
Sphincter Pressure ◽  
Coronal Section ◽  
Esophageal Sphincter ◽  
Human Esophagus

The opossum esophagus is commonly used as an animal model of the human esophagus. We used esophageal manometry in normal animals to provide basal data about normal esophageal motor functions in vivo in this species. At rest, separate and distinct high pressure zones can be recorded at the level of the lower esophageal sphincter, diaphragmatic hiatus, aortic arch, and upper esophageal sphincter. Each zone demonstrates a characteristic pattern of pressures in the radii of the coronal section and a characteristic response to swallowing. The hiatal and aortic zones can be mistaken for the esophageal sphincters. Pressures in the sphincters fall with swallowing. Peristalsis is not bolus-dependent and occurs with 98% of swallows. Pressures generated by peristalsis are greater in the middle of the esophagus than at the ends. Values for resting lower esophageal sphincter pressure and the characteristics of peristalsis were reproducible between different studies in the same animals.

Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor

2011 ◽  
Vol 115 (6) ◽  
pp. 1131-1138 ◽  
Author(s):  
Nikolay L. Martirosyan ◽  
Daniel D. Cavalcanti ◽  
Jennifer M. Eschbacher ◽  
Peter M. Delaney ◽  
Adrienne C. Scheck ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Tumor Cells ◽  
Near Infrared ◽  
Tumor Resection ◽  
Tumor Detection ◽  
Normal Brain ◽  
Tumor Margins ◽  
Confocal Endomicroscopy ◽  
Infiltrative Tumor

Object Infiltrative tumor resection is based on regional (macroscopic) imaging identification of tumorous tissue and the attempt to delineate invasive tumor margins in macroscopically normal-appearing tissue, while preserving normal brain tissue. The authors tested miniaturized confocal fiberoptic endomicroscopy by using a near-infrared (NIR) imaging system with indocyanine green (ICG) as an in vivo tool to identify infiltrating glioblastoma cells and tumor margins. Methods Thirty mice underwent craniectomy and imaging in vivo 14 days after implantation with GL261-luc cells. A 0.4 mg/kg injection of ICG was administered intravenously. The NIR images of normal brain, obvious tumor, and peritumoral zones were collected using the handheld confocal endomicroscope probe. Histological samples were acquired from matching imaged areas for correlation of tissue images. Results In vivo NIR wavelength confocal endomicroscopy with ICG detects fluorescence of tumor cells. The NIR and ICG macroscopic imaging performed using a surgical microscope correlated generally to tumor and peritumor regions, but NIR confocal endomicroscopy performed using ICG revealed individual tumor cells and satellites within peritumoral tissue; a definitive tumor border; and striking fluorescent microvascular, cellular, and subcellular structures (for example, mitoses, nuclei) in various tumor regions correlating with standard clinical histological features and known tissue architecture. Conclusions Macroscopic fluorescence was effective for gross tumor detection, but NIR confocal endomicroscopy performed using ICG enhanced sensitivity of tumor detection, providing real-time true microscopic histological information precisely related to the site of imaging. This first-time use of such NIR technology to detect cancer suggests that combined macroscopic and microscopic in vivo ICG imaging could allow interactive identification of microscopic tumor cell infiltration into the brain, substantially improving intraoperative decisions.

scholarly journals A miniaturized, tethered, spectrally‐encoded confocal endomicroscopy capsule

2019 ◽  
Vol 51 (5) ◽  
pp. 452-458 ◽  
Author(s):  
Dongkyun Kang ◽  
Dukho Do ◽  
Jiheun Ryu ◽  
Catriona N. Grant ◽  
Sarah L. Giddings ◽  
...  
Keyword(s):  
Confocal Endomicroscopy ◽  
Spectrally Encoded
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