Toxicity of photodynamic therapy after combined external beam radiotherapy and intraluminal brachytherapy for carcinoma of the upper aerodigestive tract

2001 ◽  
Vol 28 (3) ◽  
pp. 278-281 ◽  
Author(s):  
Nicholas J. Sanfilippo ◽  
Alex Hsi ◽  
Albert S. DeNittis ◽  
Gregory G. Ginsberg ◽  
Michael L. Kochman ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
External Beam Radiotherapy ◽  
Aerodigestive Tract ◽  
External Beam ◽  
Upper Aerodigestive Tract ◽  
Intraluminal Brachytherapy

Photodynamic therapy in the upper aerodigestive tract. Overview and outlook

2016 ◽  
Vol 9 (11-12) ◽  
pp. 1302-1313 ◽  
Author(s):  
Veronika Volgger ◽  
Christian Stephan Betz
Keyword(s):  
Photodynamic Therapy ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract

External beam radiotherapy combined with intraluminal brachytherapy in esophageal carcinoma

2012 ◽  
Vol 102 (2) ◽  
pp. 303-308 ◽  
Author(s):  
Christina T. Muijs ◽  
Jannet C. Beukema ◽  
Veronique E. Mul ◽  
John Th. Plukker ◽  
Nanna M. Sijtsema ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Intraluminal Brachytherapy

scholarly journals Photodynamic Therapy for 101 Early Cancers of the Upper Aerodigestive Tract, the Esophagus, and the Bronchi: A Single-Institution Experience

1999 ◽  
Vol 5 (3) ◽  
pp. 145-154 ◽  
Author(s):  
A. Radu ◽  
P. Grosjean ◽  
Ch. Fontolliet ◽  
G. Wagnieres ◽  
A. Woodtli ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Early Stage ◽  
Red Light ◽  
Green Light ◽  
Tracheobronchial Tree ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Photofrin Ii ◽  
Significant Difference ◽  
Radical Therapy

Cancer, when detected at an early stage, has a very good probability of being eradicated by surgery or radiotherapy. However, less aggressive treatments also tend to provide high rates of cure without the side effects of radical therapy. We report on the results of our clinical experience with photodynamic therapy (PDT) for the treatment of early carcinomas in the upper aerodigestive tract, the esophagus, and the tracheobronchial tree. Sixty-four patients with 101 squamous cell carcinomas were treated with three different photosensitizers: hematoporphyrin derivative (HPD), Photofrin II, and tetra (m-hydroxyphenyl)chlorin (mTHPC). Seventy-seven (76%) tumors showed a complete rsponse with no recurrence after a mean follow-up period of 27 months. There was no significant difference in terms of cure rates among the three dyes. However, mTHPC has a stronger phototoxicity and induces a shorter skin photosensitization than either of the other photosensitizers. There were eight major complications: three esophagotracheal fistulae after illumination with red light in the esophagus, two esophageal stenoses following 360° circumferential irradiation, and three bronchial stenoses. Illumination with the less penetrating green light and the use of a 180° or 240° windowed cylindrical light distributor render the risk of complications in the esophagus essentially impossible, without reducing the efficacy of the treatment. Therefore, PDT may be considered as a safe and effective treatment for early carcinomas of the upper aerodigestive tract, the esophagus, and the tracheobronchial tree.

External Beam Radiotherapy and Intraluminal Brachytherapy in Advanced Inoperable Esophageal Cancer

2001 ◽  
Vol 24 (2) ◽  
pp. 128-130 ◽  
Author(s):  
S. Vivekanandam ◽  
K. S. Reddy ◽  
K. Velavan ◽  
V. Balasundaram ◽  
S. Ranga Rao ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Intraluminal Brachytherapy

scholarly journals Photodynamic Therapy with Verteporfin for Choroidal Metastasis Refractory to Radiotherapy

2019 ◽  
Vol 12 (3) ◽  
pp. 861-865
Author(s):  
Raymond Zhou ◽  
David Reichstein
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Metastatic Breast Cancer ◽  
Primary Breast Cancer ◽  
External Beam Radiotherapy ◽  
Metastatic Breast ◽  
Eye Disease ◽  
External Beam ◽  
Choroidal Metastasis

A 54-year old female with longstanding metastatic breast cancer was referred for management of choroidal metastases. She was first treated with external beam radiotherapy and experienced some response before later suffering progression of her eye disease. We then treated her using full fluence Photodynamic therapy (PDT) with Verteporfin, which resulted in regression of her lesions until she passed away due to other illnesses. This is the first documented successful application of PDT for choroidal metastasis from a primary breast cancer refractory to external beam radiotherapy.

PO-384 COMBINED EXTERNAL BEAM RADIOTHERAPY AND INTRALUMINAL BRACHYTHERAPY IN THE TREATMENT OF ESOPHAGEAL CANCER

2012 ◽  
Vol 103 ◽  
pp. S153
Author(s):  
D. Scepanovic ◽  
M. Pobijakova ◽  
P. Lukacko ◽  
M. Masar ◽  
Z. Dolinska ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Intraluminal Brachytherapy

Photodynamic Therapy for Cancer of the Upper Aerodigestive Tract Using Tetra(m-hydroxyphenyl)chlorin

1996 ◽  
Vol 14 (5) ◽  
pp. 281-287 ◽  
Author(s):  
PIERRE GROSJEAN ◽  
JEAN-FRANÇOIS SAVARY ◽  
JÉRÔME MIZERET ◽  
GEORGES WAGNIERES ◽  
ALAIN WOODTLI ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract
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