Collaborative Achievements and Challenges for Our 10‐YR River Research Effort

2021 ◽  
Author(s):  
Juliana D'Andrilli ◽  
Marc Peipoch ◽  
Robert A. Payn ◽  
Michael DeGrandpre ◽  
H. Maurice Valett
Keyword(s):  
Research Effort

Ruthenium red and alcian blue effects on outer structures of methanotrophic bacteria

1988 ◽  
Vol 46 ◽  
pp. 72-73
Author(s):  
T.A. Fassel ◽  
M.J. Schaller ◽  
C.C. Remsen
Keyword(s):  
Research Effort ◽  
Ruthenium Red ◽  
Outer Cell ◽  
Methanotrophic Bacteria ◽  
En Bloc ◽  
Methylosinus Trichosporium ◽  
Wall Structures ◽  
Methylomonas Albus ◽  
Type Strains ◽  
Outer Cell Wall

Methane, a contributor to the “greenhouse effect”, is oxidized in the natural environment by methanotrophic bacteria. As part of a comprehensive research effort, we have been examining the ultrastructure of methanotrophs. These microorganisms have complex outer cell wall structures similar to those frequently found in other chemol itho- trophic bacteria. (1,2)In our work, we have focused on the “type” strains of Methylomonas albus BG8 and Methylosinus trichosporium OB3b. Between Spurr and LR White embedding resins, we found a difference 1n the preservation of an outer cup layer of BG8 external to the peripheral membranes. Cells from the same sample embedded in Spurr consistently lacked this feature (FIG. 1). This effect was overcome by an en bloc ruthenium red (RR) protocol that resulted in successful retention of the cup layer in Spurr resin (FIG. 2). For OB3b cells, the en bloc RR protocol resulted in an exterior bead feature distinguishable in thin section (FIG. 4) that previously was seen only by SEM.

Biotelemetry and Computer Analysis of Electrocardiograms

1969 ◽  
Vol 08 (03) ◽  
pp. 120-127 ◽  
Author(s):  
P. R. Amlinger
Keyword(s):  
Computer Analysis ◽  
Rural Areas ◽  
Applied Research ◽  
Research Effort ◽  
Pilot Project ◽  
Modern Medicine ◽  
Modern Technology ◽  
Long Distance ◽  
Regional Medical ◽  
Medical Program

Routine transmission of electrocardiograms and their computer interpretation via long-distance telephone lines has been proven feasible in the Automated Electrocardiogram Project of the Missouri Regional Medical Program. Though this Pilot Project — the first on a state-wide basis — is still viewed as an applied research effort rather than a service, such biotelemetry is rapidly gaining acceptance as a medium to bring modern medicine, through modern technology, to urban and remote rural areas as well, where it is most needed.The computer executes all the wave measuraments and calculations with incredible speed. It takes over a most boring, repetitive part of the physician’s work. However, it can only follow the instructions of the diagnostic program, compiled by expert cardiologists. Thus, it is an ever-ready, never-tiring servant for the physician and his patients.

Factors Affecting Driver Injury Severity in the Wrong-Way Crash: Accounting for Potential Heterogeneity in Means and Variances of Random Parameters

2021 ◽  
pp. 036119812110098
Author(s):  
Miao Yu ◽  
Jinxing Shen ◽  
Changxi Ma
Keyword(s):  
High Speed ◽  
Injury Severity ◽  
Unobserved Heterogeneity ◽  
Research Effort ◽  
Random Parameter ◽  
Policy Implications ◽  
Contributing Factors ◽  
Severe Injuries ◽  
Data Set ◽  
Severity Levels

Because of the high percentage of fatalities and severe injuries in wrong-way driving (WWD) crashes, numerous studies have focused on identifying contributing factors to the occurrence of WWD crashes. However, a limited number of research effort has investigated the factors associated with driver injury-severity in WWD crashes. This study intends to bridge the gap using a random parameter logit model with heterogeneity in means and variances approach that can account for the unobserved heterogeneity in the data set. Police-reported crash data collected from 2014 to 2017 in North Carolina are used. Four injury-severity levels are defined: fatal injury, severe injury, possible injury, and no injury. Explanatory variables, including driver characteristics, roadway characteristics, environmental characteristics, and crash characteristics, are used. Estimation results demonstrate that factors, including the involvement of alcohol, rural area, principal arterial, high speed limit (>60 mph), dark-lighted conditions, run-off-road collision, and head-on collision, significantly increase the severity levels in WWD crashes. Several policy implications are designed and recommended based on findings.

scholarly journals Phishing for Long Tails: Examining Organizational Repeat Clickers and Protective Stewards

SAGE Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 215824402199065
Author(s):  
Matthew Canham ◽  
Clay Posey ◽  
Delainey Strickland ◽  
Michael Constantino
Keyword(s):  
Research Effort ◽  
Time Frame ◽  
Future Research ◽  
Negative Behaviors ◽  
Computer Abuse ◽  
Positive Behaviors ◽  
Phishing Attacks ◽  
Long Tails ◽  
Motivated Behaviors ◽  
External Actors

Organizational cybersecurity efforts depend largely on the employees who reside within organizational walls. These individuals are central to the effectiveness of organizational actions to protect sensitive assets, and research has shown that they can be detrimental (e.g., sabotage and computer abuse) as well as beneficial (e.g., protective motivated behaviors) to their organizations. One major context where employees affect their organizations is phishing via email systems, which is a common attack vector used by external actors to penetrate organizational networks, steal employee credentials, and create other forms of harm. In analyzing the behavior of more than 6,000 employees at a large university in the Southeast United States during 20 mock phishing campaigns over a 19-month period, this research effort makes several contributions. First, employees’ negative behaviors like clicking links and then entering data are evaluated alongside the positive behaviors of reporting the suspected phishing attempts to the proper organizational representatives. The analysis displays evidence of both repeat clicker and repeat reporter phenomena and their frequency and Pareto distributions across the study time frame. Second, we find that employees can be categorized according to one of the four unique clusters with respect to their behavioral responses to phishing attacks—“Gaffes,” “Beacons,” “Spectators,” and “Gushers.” While each of the clusters exhibits some level of phishing failures and reports, significant variation exists among the employee classifications. Our findings are helpful in driving a new and more holistic stream of research in the realm of all forms of employee responses to phishing attacks, and we provide avenues for such future research.

scholarly journals Analgesia for Sheep in Commercial Production: Where to Next?

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1127
Author(s):  
Alison Small ◽  
Andrew David Fisher ◽  
Caroline Lee ◽  
Ian Colditz
Keyword(s):  
Research Effort ◽  
Mitigation Strategies ◽  
Worth Living ◽  
Life Worth Living ◽  
The Past ◽  
Considerable Research ◽  
Husbandry Practices ◽  
Industry Practice ◽  
Successful Launch ◽  
Inflammatory Drugs

Increasing societal and customer pressure to provide animals with ‘a life worth living’ continues to apply pressure on livestock production industries to alleviate pain associated with husbandry practices, injury and illness. Over the past 15–20 years, there has been considerable research effort to understand and develop mitigation strategies for painful husbandry procedures in sheep, leading to the successful launch of analgesic approaches specific to sheep in a number of countries. However, even with multi-modal approaches to analgesia, using both local anaesthetic and non-steroidal anti-inflammatory drugs (NSAID), pain is not obliterated, and the challenge of pain mitigation and phasing out of painful husbandry practices remains. It is timely to review and reflect on progress to date in order to strategically focus on the most important challenges, and the avenues which offer the greatest potential to be incorporated into industry practice in a process of continuous improvement. A structured, systematic literature search was carried out, incorporating peer-reviewed scientific literature in the period 2000–2019. An enormous volume of research is underway, testament to the fact that we have not solved the pain and analgesia challenge for any species, including our own. This review has highlighted a number of potential areas for further research.

scholarly journals Quantiles as Robust Probes of Non-Gaussianity in 21-cm Images

2021 ◽  
Author(s):  
Alon Banet ◽  
Rennan Barkana ◽  
Anastasia Fialkov ◽  
Or Guttman
Keyword(s):  
Galactic Halo ◽  
Angular Resolution ◽  
Research Effort ◽  
First Stars ◽  
X Ray ◽  
Global Signal ◽  
Radio Background ◽  
Halo Masses ◽  
The Universe ◽  
Cosmic History

Abstract The epoch in which the first stars and galaxies formed is among the most exciting unexplored eras of the Universe. A major research effort is focused on probing this era with the 21-cm spectral line of hydrogen. While most research focuses on statistics like the 21-cm power spectrum or the sky-averaged global signal, there are other ways to analyze tomographic 21-cm maps, which may lead to novel insights. We suggest statistics based on quantiles as a method to probe non-Gaussianities of the 21-cm signal. We show that they can be used in particular to probe the variance, skewness, and kurtosis of the temperature distribution, but are more flexible and robust than these standard statistics. We test these statistics on a range of possible astrophysical models, including different galactic halo masses, star-formation efficiencies, and spectra of the X-ray heating sources, plus an exotic model with an excess early radio background. Simulating data with angular resolution and thermal noise as expected for the Square Kilometre Array (SKA), we conclude that these statistics can be measured out to redshifts above 20 and offer a promising statistical method for probing early cosmic history.

scholarly journals Characterization of Austenitic Stainless Steels with Regard to Environmentally Assisted Fatigue in Simulated Light Water Reactor Conditions

Metals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 307
Author(s):  
Matthias Bruchhausen ◽  
Gintautas Dundulis ◽  
Alec McLennan ◽  
Sergio Arrieta ◽  
Tim Austin ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Fatigue Life ◽  
Elevated Temperature ◽  
Strain Rate ◽  
Power Plants ◽  
Research Effort ◽  
Hold Time ◽  
Strain Range ◽  
Austenitic Steels ◽  
Mean Strain

A substantial amount of research effort has been applied to the field of environmentally assisted fatigue (EAF) due to the requirement to account for the EAF behaviour of metals for existing and new build nuclear power plants. We present the results of the European project INcreasing Safety in NPPs by Covering Gaps in Environmental Fatigue Assessment (INCEFA-PLUS), during which the sensitivities of strain range, environment, surface roughness, mean strain and hold times, as well as their interactions on the fatigue life of austenitic steels has been characterized. The project included a test campaign, during which more than 250 fatigue tests were performed. The tests did not reveal a significant effect of mean strain or hold time on fatigue life. An empirical model describing the fatigue life as a function of strain rate, environment and surface roughness is developed. There is evidence for statistically significant interaction effects between surface roughness and the environment, as well as between surface roughness and strain range. However, their impact on fatigue life is so small that they are not practically relevant and can in most cases be neglected. Reducing the environmental impact on fatigue life by modifying the temperature or strain rate leads to an increase of the fatigue life in agreement with predictions based on NUREG/CR-6909. A limited sub-programme on the sensitivity of hold times at elevated temperature at zero force conditions and at elevated temperature did not show the beneficial effect on fatigue life found in another study.

scholarly journals Novel Treatments and Technologies Applied to the Cure of Neuroblastoma

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 482
Author(s):  
Irene Paraboschi ◽  
Laura Privitera ◽  
Gabriela Kramer-Marek ◽  
John Anderson ◽  
Stefano Giuliani
Keyword(s):  
Research Effort ◽  
Treatment Strategies ◽  
Adverse Outcomes ◽  
Treatment Protocols ◽  
Ongoing Research ◽  
Hematopoietic Stem ◽  
Novel Treatments ◽  
Therapeutic Modalities ◽  
High Risk Disease ◽  
Novel Treatment Strategies

Neuroblastoma (NB) is the most common extracranial solid tumour in childhood, accounting for approximately 15% of all cancer-related deaths in the paediatric population1. It is characterised by heterogeneous clinical behaviour in neonates and often adverse outcomes in toddlers. The overall survival of children with high-risk disease is around 40–50% despite the aggressive treatment protocols consisting of intensive chemotherapy, surgery, radiation therapy and hematopoietic stem cell transplantation2,3. There is an ongoing research effort to increase NB’s cellular and molecular biology knowledge to translate essential findings into novel treatment strategies. This review aims to address new therapeutic modalities emerging from preclinical studies offering a unique translational opportunity for NB treatment.

scholarly journals Perceiving Music Through the Lens of Synaesthesia and Absolute Pitch

Perception ◽  
2021 ◽  
pp. 030100662110344
Author(s):  
Solange Glasser
Keyword(s):  
Music Perception ◽  
Research Effort ◽  
Absolute Pitch ◽  
Potential Relationship ◽  
Current Thinking ◽  
Music Literature ◽  
Behavioural Evidence

Synaesthesia and absolute pitch (AP) are two rare conditions that occur more frequently within populations of artistic professionals. Current thinking surrounding synaesthesia and AP and their relationship to music perception form the focus of this article. Given that synaesthesia has rarely been discussed in the music literature, the article surveys and consolidates general neurobiological, psychological, and behavioural evidence to summarise what is currently known on this topic, in order to link this back to the conditions that most relate to music. In contrast, research on AP is now well established in the music literature, but the important gap of linking AP to other conditions such as synaesthesia has yet to be fully explored. This article investigates the potential relationship between synaesthesia and AP for musicians who possess both conditions by systematically comparing the definitions, classifications, prevalence, diagnoses, and impacts on music perception of synaesthesia and AP and provides insights into the varying states of the literature and knowledge of both conditions. In so doing, this article aims to facilitate a greater understanding of music and auditory forms of synaesthesia and their interaction with AP and encourage increased research effort on this important topic.

scholarly journals Classification of groundwater suitability for irrigation purposes using a comprehensive approach based on the AHP and GIS techniques in North Kurdufan Province, Sudan

2021 ◽  
Vol 11 (7) ◽  
Author(s):  
Elsiddig Eldaw ◽  
Tao Huang ◽  
Adam Khalifa Mohamed ◽  
Yahaya Mahama
Keyword(s):  
Water Quality ◽  
Spatial Distribution ◽  
Groundwater Quality ◽  
Irrigation Water ◽  
Research Effort ◽  
Sodium Absorption ◽  
Irrigation Water Quality ◽  
Middle Income ◽  
Sodium Absorption Ratio ◽  
Deep Aquifers

AbstractDeterioration of groundwater quality due to drastic human interventions is rising at an alarming rate particularly in lower- and middle-income countries. Yet, limited research effort has been devoted to monitoring and ascertaining groundwater quality. The present study develops a comprehensive irrigation water quality index (IWQI) for rating water quality of shallow and deep aquifers in North Kurdufan province, Sudan. The new approach is developed to overcome the deficiencies of the existing irrigation indices and coming up with a unified decision for classifying water quality for irrigation purposes. Because of these indices like permeability index (PI), sodium absorption ratio (SAR), etc., depending on specific elements, entirely subjective, as well as the great variations in their results, particularly when classifying water quality. Thus, IWQI is created based on eight indices that are generally used to evaluate irrigation water quality, plus three physicochemical parameters have been proven an impact on water quality. The analytic hierarchy process (AHP) is applied to minimize the subjectivity at assign parameter weights under multiple criteria decision analysis tools (MCDA). The spatial distribution of IWQI agrees with the spatial distribution of the most parameters. The results of our approach reveal that the majority of samples are suitable for irrigation uses for both aquifers except few wells in the confined aquifer. Also, noted that there are very variations in the irrigation indices results for classifying water quality. The comparison result showed that the new index robust, fair calculations and has best classifying of water quality.

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