scholarly journals Analgesia for Sheep in Commercial Production: Where to Next?

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1127
Author(s):  
Alison Small ◽  
Andrew David Fisher ◽  
Caroline Lee ◽  
Ian Colditz
Keyword(s):  
Research Effort ◽  
Mitigation Strategies ◽  
Worth Living ◽  
Life Worth Living ◽  
The Past ◽  
Considerable Research ◽  
Husbandry Practices ◽  
Industry Practice ◽  
Successful Launch ◽  
Inflammatory Drugs

Increasing societal and customer pressure to provide animals with ‘a life worth living’ continues to apply pressure on livestock production industries to alleviate pain associated with husbandry practices, injury and illness. Over the past 15–20 years, there has been considerable research effort to understand and develop mitigation strategies for painful husbandry procedures in sheep, leading to the successful launch of analgesic approaches specific to sheep in a number of countries. However, even with multi-modal approaches to analgesia, using both local anaesthetic and non-steroidal anti-inflammatory drugs (NSAID), pain is not obliterated, and the challenge of pain mitigation and phasing out of painful husbandry practices remains. It is timely to review and reflect on progress to date in order to strategically focus on the most important challenges, and the avenues which offer the greatest potential to be incorporated into industry practice in a process of continuous improvement. A structured, systematic literature search was carried out, incorporating peer-reviewed scientific literature in the period 2000–2019. An enormous volume of research is underway, testament to the fact that we have not solved the pain and analgesia challenge for any species, including our own. This review has highlighted a number of potential areas for further research.

Ensemble Intercontemporain at 40, Philharmonie de Paris

Tempo ◽  
2017 ◽  
Vol 71 (282) ◽  
pp. 80-81
Author(s):  
Stephanie Jones
Keyword(s):  
First World War ◽  
Original Sin ◽  
First Century ◽  
Worth Living ◽  
World War ◽  
Life Worth Living ◽  
The Past ◽  
The First World War ◽  
Bernard Stiegler ◽  
First World

In response to Paul Valéry's words after the First World War in La Crise de l'esprit – ‘We later civilisations … we too now know that we are mortal’ – the French philosopher Bernard Stiegler remarks, in his own chapter entitled ‘Apocalypse Without God’ in his What Makes Life Worth Living, We too, earthlings of the twenty-first century know that we are capable of self-destruction. And if in the past the possibility of such an extinction of our kind was inconceivable other than as the consequence of God's anger – of original sin – today there is no longer any religious reference at the origin of this extreme global pessimism’ (p. 9).

scholarly journals Hog Price Flexibilities as Related to Cycle Phases

1972 ◽  
Vol 4 (1) ◽  
pp. 119-122
Author(s):  
D. W. Parvin
Keyword(s):  
Research Effort ◽  
Pork Production ◽  
The Past ◽  
Net Returns ◽  
Considerable Research ◽  
Farm Price ◽  
Price Relationship ◽  
The Relationship

During the past decade, commercial pork production has varied from 723 to 1,372 million pounds (dressed weight) per month. For the same period, the average farm price of hogs has ranged from $12 to $30. Consequently, net returns to hog producers were highly variable.Agricultural economists have devoted considerable research effort to estimating the quantity-price relationship for pork. Purcell and Raunikar suggest that the relationship between price and quantity of pork may differ for positive and negative changes in the price of pork at the retail level.

Chemistry and applications of cyanoximes and their metal complexes

2019 ◽  
Vol 48 (23) ◽  
pp. 7985-8013 ◽  
Author(s):  
Nikolay Gerasimchuk
Keyword(s):  
Metal Complexes ◽  
General Formula ◽  
Research Effort ◽  
Organic Ligands ◽  
New Class ◽  
The Past ◽  
Considerable Research ◽  
Electron Withdrawing Group

During the past three decades, considerable research effort has been dedicated to a new class of organic ligands – cyanoximes – which have the general formula NC–C(NOH)-R, where R is an electron-withdrawing group. In total, 44 different cyanoximes were prepared and characterized thus far.

Current Studies of Aspirin as an Anticancer Agent and Strategies to Strengthen its Therapeutic Application in Cancer

2020 ◽  
Vol 26 ◽  
Author(s):  
Phuong H.L. Tran ◽  
Beom-Jin Lee ◽  
Thao T.D. Tran
Keyword(s):  
Anticancer Agent ◽  
Mechanisms Of Action ◽  
Aspirin Therapy ◽  
Therapeutic Application ◽  
Cancer Treatments ◽  
Anticancer Properties ◽  
Cancer Management ◽  
Risk Of Bleeding ◽  
The Past ◽  
Inflammatory Drugs

: Aspirin has emerged as a promising intervention in cancer in the past decade. However, there are existing controversies regarding the anticancer properties of aspirin as its mechanism of action has not been clearly defined. In addition, the risk of bleeding in the gastrointestinal tract from aspirin is another consideration that requires medical and pharmaceutical scientists to work together to develop more potent and safe aspirin therapy in cancer. This review presents the most recent studies of aspirin with regard to its role in cancer prevention and treatment demonstrated by highlighted clinical trials, mechanisms of action as well as approaches to develop aspirin therapy best beneficial to cancer patients. Hence, this review provides readers with an overview of aspirin research in cancer that covers not only the unique features of aspirin, which differentiates aspirin from other non-steroidal anti-inflammatory drugs (NSAIDs), but also strategies that can be used in the development of drug delivery systems carrying aspirin for cancer management. These studies convey optimistic messages on continuing efforts of scientist on the way of developing an effective therapy for even patients with a low response to current cancer treatments.

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

Explosive Removal of Concrete From Reinforced Walls

2007 ◽  
Author(s):  
Denis D. Rickman ◽  
John Q. Ehrgott ◽  
Stephen A. Akers ◽  
Jon E. Windham ◽  
Dennis W. Moore
Keyword(s):  
Explosive Charge ◽  
Research Effort ◽  
Us Army ◽  
Steel Reinforced Concrete ◽  
The Past ◽  
The Us ◽  
Development Center ◽  
The Relationship ◽  
Improved Methods ◽  
Combat Environment

During the past several years, the US Army has focused considerable attention toward developing improved methods for breaching walls in the urban combat environment. A major thrust area is centered on finding improved methods to breach the toughest wall type that Army units are likely to face: a double (steel) reinforced concrete (RC) wall. One impediment to this effort is that the relationship between the contact explosive charge configuration and the quantity of concrete removed has not been thoroughly understood. The U.S. Army Engineer Research and Development Center has conducted a research effort to better define the effectiveness of various explosive charge configurations in breaching RC walls. This paper presents a discussion of results from this research.

An Examined Life Worth Living

1998 ◽  
Vol 15 (6) ◽  
pp. 22
Author(s):  
Gertrude Reif Hughes ◽  
Hazel Barnes
Keyword(s):  
Worth Living ◽  
Life Worth Living
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