scholarly journals Prognostic factors after transoral resection of early hypopharyngeal cancer

2021 ◽  
Author(s):  
Keisuke Iritani ◽  
Daryl Anne A. Mundo ◽  
Shinobu Iwaki ◽  
Kuriko Masuda ◽  
Maki Kanzawa ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Hypopharyngeal Cancer ◽  
Transoral Resection

scholarly journals Hypopharyngeal cancer treatment based on definitive radiotherapy: who is suitable for laryngeal preservation?

2007 ◽  
Vol 122 (5) ◽  
pp. 506-512 ◽  
Author(s):  
S-W Chen ◽  
M-H Tsai ◽  
S-N Yang ◽  
J-A Liang ◽  
A-C Shiau ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Proportional Hazards Model ◽  
Multivariate Analyses ◽  
Local Relapse ◽  
Hypopharyngeal Cancer ◽  
Stage I ◽  
Stage Iii ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Laryngeal Preservation

AbstractAims:To investigate prognostic factors for survival and locoregional control in patients with stage I–IVA hypopharyngeal cancer treated with laryngeal preservation radiotherapy.Methods:This study was a retrospective analysis of 108 patients with stage I–IVA squamous cell carcinoma of the hypopharynx, treated with laryngeal preservation radiotherapy. Actuarial survival, disease-specific survival and local relapse-free survival were calculated, and multivariate analyses were performed using Cox's proportional hazards model.Results:After a median follow-up duration of 39 months, the five-year local relapse-free survival rate was 35 per cent for all patients, 66 per cent for those with stage I–II disease, 46 per cent for those with stage III disease and 20 per cent for those with stage IVA disease (p = 0.004). Multivariate analyses showed that tumour and node stages were independent prognostic factors.Conclusions:Patients with stage I–II disease were suitable for laryngeal preservation radiotherapy. For most patients with stage III–IVA disease, other than those who were T1 N1 or T2 N1, the treatment results were poor.

scholarly journals Lifestyle habits as prognostic factors in survival of laryngeal and hypopharyngeal cancer: A multicentric European study

2005 ◽  
Vol 117 (6) ◽  
pp. 992-995 ◽  
Author(s):  
Rajesh P. Dikshit ◽  
Paolo Boffetta ◽  
Christine Bouchardy ◽  
Franco Merletti ◽  
Paolo Crosignani ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Hypopharyngeal Cancer ◽  
European Study ◽  
Lifestyle Habits

scholarly journals Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Volker Rudat ◽  
Salia Ahmet-Osman ◽  
Oliver Schramm ◽  
Andreas Dietz
Keyword(s):  
Prognostic Factors ◽  
Postoperative Radiotherapy ◽  
Statistical Significance ◽  
Univariate Analysis ◽  
Hypopharyngeal Cancer ◽  
Time Interval ◽  
Definitive Radiotherapy ◽  
Simultaneous Radiochemotherapy ◽  
N Classification ◽  
The Impact

Purpose. To compare the impact of prognostic factors of patients treated with definitive radio(chemo)therapy versus patients treated with surgery and postoperative radiotherapy for squamous cell carcinoma of the oro- and hypopharynx.Patients and Methods. 162 patients treated with definitive radiotherapy and 126 patients treated with postoperative radiotherapy were retrospectively analysed. The impact of the prognostic factors gender, age, total tumor volume (TTV), pre-radiotherapy hemoglobin level (Hb-level), tumor site, T- and N-classification, radiotherapy interruptions >5 days, radiotherapy versus simultaneous radiochemotherapy, R-status and time interval between surgery and radiotherapy were investigated.Results. The median follow-up time for the censored patients treated with definitive radio(chemo)therapy was 28.5 months and for postoperative radiotherapy 36.5 months. On univariate analysis, the TTV, Hb-level, and simultaneous radiochemotherapy had a significant impact on the survival of patients treated with definitive radio(chemo)therapy. For patients treated with postoperative radiotherapy, only the TTV showed a statistical trend for the survival (P=0.13). On multivariate analysis, the TTV and simultaneous radiochemotherapy maintained their statistical significance for patients treated with definitive raditherapy, and the TTV, the statistical trend for patients treated with postoperative radiotherapy (P=0.19).Conclusions. The TTV was the predominant prognostic factor for both, patients treated with definitive or postoperative radiotherapy.

Five- and ten-year survival of squamous cell carcinoma of the head and neck in northern Thailand: a multivariate analysis

2020 ◽  
pp. 1-6
Author(s):  
Somvilai Chakrabandhu ◽  
Walaithip Bunyatisai ◽  
Patumrat Sripan ◽  
Patrinee Traisathit ◽  
Imjai Chitapanarux
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Hypopharyngeal Cancer ◽  
Cancer Site ◽  
Cox Proportional Hazard ◽  
Cox Proportional Hazard Regression

Abstract Aim: To report 5- and 10-year overall survival (OS) outcomes of squamous cell carcinoma of the head and neck and identify prognostic factors. Methods: Data on 2,095 patients at Maharaj Nakorn Chiang Mai Hospital, Thailand between 2007 and 2014 were analysed using the Kaplan–Meyer method to estimate 5- and 10-year OS rates. Cox proportional hazard regression models were applied to assess the independent prognostic factors of survival. Results: 8·7% had hypopharyngeal cancer, 19·7% laryngeal, 53·3% oral cavity and 18·3% oropharyngeal. Two-thirds of the patients had locally advanced stage (III–IVB). Five- and ten-year OS rates were 30·1 and 22·8%, respectively. Conclusions: Cancer site, stage and age at diagnosis were associated with mortality, highlighting the importance of prevention and early detection.

Treatment results and prognostic factors in locally advanced hypopharyngeal cancer

2008 ◽  
Vol 128 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Moon-Sing Lee ◽  
Hsu-Chueh Ho ◽  
Shih-Hsuan Hsiao ◽  
Juen-Haur Hwang ◽  
Ching-Chih Lee ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Locally Advanced ◽  
Hypopharyngeal Cancer ◽  
Treatment Results

scholarly journals T-status and an oral fluoropyrimidine, S-1, adjuvant chemotherapy are prognostic factors in reduced-RADPLAT for resectable hypopharyngeal cancer

2016 ◽  
Vol 136 (8) ◽  
pp. 834-840
Author(s):  
Naohiro Wakisaka ◽  
Nobuyuki Hirai ◽  
Satoru Kondo ◽  
Mitsuharu Aga ◽  
Yosuke Nakanishi ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Adjuvant Chemotherapy ◽  
Hypopharyngeal Cancer ◽  
Oral Fluoropyrimidine
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