The Correlation Between Endolymphatic Hydrops and Clinical Features of Meniere Disease

2020 ◽  
Vol 131 (1) ◽  
Author(s):  
Weidong Zhang ◽  
Lian Hui ◽  
Bo Zhang ◽  
Ling Ren ◽  
Jingyi Zhu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Menière Disease

scholarly journals Bridging the gap between chronic cerebrospinal venous insufficiency and Ménière disease

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Dario C. Alpini ◽  
Pietro M. Bavera ◽  
Federica Di Berardino ◽  
Stefania Barozzi ◽  
Piero Cecconi ◽  
...  
Keyword(s):  
Inner Ear ◽  
Major Part ◽  
Venous Insufficiency ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Number Of Patients ◽  
Hydraulic Mechanism ◽  
Collateral Pathways ◽  
Menière Disease ◽  
Global Brain

Ménière disease (MD) is a chronic illness of the inner ear that affects a substantial number of patients every year worldwide. Because of a dearth of well-controlled studies, the medical and surgical management of MD remains quite empirical. The main reason is that it is very difficult to investigate patients affected with Certain MD due to the post-mortem criterion necessary for this diagnostic grade. Although Endolymphatic Hydrops (EH) is the worldwide accepted mechanism of MD, the causes that induce it are still not clear. In fact MD has been correlated mostly to a wide and different disturbances ranging from trauma to sleep disorders. It is nowadays sufficiently demonstrated that Chronic Cerebro Spinal Venous Insufficiency (CCSVI) is very frequent in MD. Even if CCSVI may potentially induce EH through a pure hydraulic mechanism CCSVI, per se does not explain how the various disorders correlated with MD may interact with CCSVI and provoke EH. The aim of this review is an attempt to approach MD into the context of the more recent findings about the global brain waste clearance system, to which inner ear is anatomically and functionally connected, in order to build a reasonable model of MD pathogenesis. The major part of the diseases correlated to MD may act on the inner ear disturbing the Glymphatic (GS) and/or Brain Lymphatic System (BLS) activity. The venous system interplays with GS and BLS. In this model CCSVI is considered more than a direct cause of MD rather the anatomical predisposition to develop the disease. In this model EH, and then MD, is the consequence of a failure of the compensation of the congenital venous abnormalities, anatomical compensation as collateral pathways and/or functional compensation as GS and BLS. In this model the major part of the disturbances correlated to MD and the various treatment proposed find their appropriate placement.

scholarly journals Endolymphatic hydrops imaging: Differential diagnosis in patients with Meniere disease symptoms

2017 ◽  
Vol 98 (10) ◽  
pp. 699-706 ◽  
Author(s):  
A. Attyé ◽  
M. Eliezer ◽  
A. Galloux ◽  
J. Pietras ◽  
I. Tropres ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Disease Symptoms ◽  
Menière Disease

scholarly journals Detection and Grading of Endolymphatic Hydrops in Menière Disease Using MR Imaging

2014 ◽  
Vol 35 (7) ◽  
pp. 1387-1392 ◽  
Author(s):  
K. Baráth ◽  
B. Schuknecht ◽  
A. Monge Naldi ◽  
T. Schrepfer ◽  
C.J. Bockisch ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Menière Disease

scholarly journals Value of Endolymphatic Hydrops and Perilymph Signal Intensity in Suspected Ménière Disease

2020 ◽  
Vol 41 (3) ◽  
pp. 529-534 ◽  
Author(s):  
J.M. van Steekelenburg ◽  
A. van Weijnen ◽  
L.M.H. de Pont ◽  
O.D. Vijlbrief ◽  
C.C. Bommeljé ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Endolymphatic Hydrops ◽  
Meniere Disease ◽  
Menière Disease

Relationship between Endolymphatic Hydrops and Symptoms of Meniere Disease in Acoustic Hearing

ORL ◽  
2021 ◽  
pp. 1-9
Author(s):  
Yoonkyung Oh ◽  
Jongwoo Lim ◽  
Young Sang Cho ◽  
Namkeun Kim
Keyword(s):  
Hearing Loss ◽  
Middle Ear ◽  
Basilar Membrane ◽  
Endolymphatic Hydrops ◽  
Experimental Studies ◽  
Single Frequency ◽  
Meniere Disease ◽  
Low Frequencies ◽  
Frequency Sound ◽  
Menière Disease

Hypothesis: The endolymphatic hydrops (EH) does not affect hearing loss significantly at low frequencies, whereas the hydrops affects the diplacusis. Background: There have been many arguments whether the EH cause the Meniere disease. Despite a lot of experimental studies to investigate the Meniere disease, there have been little modeling studies, which are helpful to understand the mechanism. Methods: A 3D finite element model of the human cochlea and the middle ear was used for investigation of the relationship between EH and hearing loss at low frequencies and diplacusis (2 specific symptoms of Meniere disease). While the cochlear geometry was simplified as a tapered box shape, the middle ear was based on the real geometry obtained from μCT images. EH is implemented by prestress on the basilar membrane surface in the simulation. Results: The EH did not cause significant hearing loss at low frequencies in both air- and bone-conducted hearing. Rather, this disorder caused a shift in best frequency (BF) position to the base at low frequencies below about 250 Hz. The BF shift can explain the diplacusis because a low-frequency sound can be perceived as a slightly higher frequency so that Meniere patients can perceive 2 different frequency sounds corresponding to a given single-frequency sound. Conclusion: The EH cannot be a sufficient condition for Meniere disease, whereas the hydrops can cause the diplacusis.

scholarly journals The role of magnetic resonance imaging in Ménière disease: the current state of endolymphatic hydrops evaluation

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Rafael Maffei Loureiro ◽  
Daniel Vaccaro Sumi ◽  
Marcelo Delboni Lemos ◽  
Hugo Luis de Vasconcelos Chambi Tames ◽  
Regina Lucia Elia Gomes ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endolymphatic Hydrops ◽  
Resonance Imaging ◽  
Meniere Disease ◽  
Current State ◽  
Menière Disease

Chronic cerebrospinal venous insufficiency in Ménière disease

2014 ◽  
Vol 30 (4) ◽  
pp. 274-279 ◽  
Author(s):  
Federica Di Berardino ◽  
Dario Carlo Alpini ◽  
Pietro Maria Bavera ◽  
Piero Cecconi ◽  
Mario Farabola ◽  
...  
Keyword(s):  
Venous Insufficiency ◽  
Endolymphatic Hydrops ◽  
Color Doppler ◽  
Vestibular Disorder ◽  
Predisposing Factor ◽  
Meniere Disease ◽  
Venous Flow ◽  
Chronic Cerebrospinal Venous Insufficiency ◽  
Contrast Enhanced ◽  
Menière Disease

Objectives The aim of this study was to focus on patients suffering from cochleo-vestibular disorder with and without Ménière disease (MD) in order to verify whether chronic cerebrospinal drainage abnormalities could play a role in the etiopathogenesis of endolymphatic hydrops. Methods Fifty-two volunteers were enrolled and subdivided into two groups: 24 definite MD and 28 not-MD. Both magnetic resonance venography imaging with contrast-enhanced imaging of the venous cerebrospinal system (MRV) and venous echo-color Doppler (ECD) were performed. Results MRV showed abnormalities in 83% of MD and 57% of not-MD subjects ( p < 0.001). Asymmetrical cervical venous flow, assessed by MRV, was confirmed by ECD in 62.5% of MD but in only 21.5% of not-MD subjects ( p<0.001). Conclusion Chronic cerebrospinal venous insufficiency might be the anatomical background, which provides a predisposing factor for the development of endolymphatic hydrops in MD patients.

Sign in / Sign up

Export Citation Format

Share Document