The role of elective neck dissection in patients with adenoid cystic carcinoma of the head and neck

2019 ◽  
Vol 129 (9) ◽  
pp. 2094-2104 ◽  
Author(s):  
Roy Xiao ◽  
Rosh K.V. Sethi ◽  
Allen L. Feng ◽  
Joel B. Fontanarosa ◽  
Daniel G. Deschler
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Neck Dissection ◽  
Elective Neck Dissection ◽  
Adenoid Cystic

scholarly journals Adenoid cystic carcinoma of external auditory canal: A rare disease

2021 ◽  
pp. 1-8
Author(s):  
Abdul Basit Vardag ◽  
Muhammad Hassan Danish ◽  
Muhammad Sohail Awan ◽  
Muhammad Usman Tariq ◽  
Omaima Anis Bhatti ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Neck Dissection ◽  
Rare Disease ◽  
External Auditory Canal ◽  
Squamous Cell Carcinomas ◽  
Rare Occurrence ◽  
Limited Data ◽  
Aggressive Approach ◽  
Adenoid Cystic

Abstract External auditory canal, like other epithelialized surfaces is predisposed to malignancies such as Squamous cell carcinomas (SCC), melanomas and adenocarcinomas. In this background, malignancies like adenoid cystic carcinoma (ACC) are a rare occurrence and need to be thoroughly evaluated both locally and for distant extension. The malignancy needs to be addressed with an aggressive approach surgically with adequate marginal clearance. The role of radiation is debatable considering the outcomes in the limited data. Here we present a case of a 35-year-old female who presented with otalgia and otorrhea associated a mass in the external auditory canal. After biopsy and imaging, a diagnosis of adenoid cystic carcinoma was made, and the patient was managed accordingly. Keywords: Adenoid cystic carcinoma, External auditory canal, Neck dissection Continuous...

The role of radiotherapy in the management of adenoid cystic carcinoma of the head and neck

1987 ◽  
Vol 13 (8) ◽  
pp. 1135-1141 ◽  
Author(s):  
Junichi Horiuchi ◽  
Hitoshi Shibuya ◽  
Soji Suzuki ◽  
Masamune Takeda ◽  
Minoru Takagi
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Adenoid Cystic

scholarly journals Radiation Therapy for Adenoid Cystic Carcinoma of the Head and Neck

Cancers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 6335
Author(s):  
Carlos A. Rodriguez-Russo ◽  
Jacqueline C. Junn ◽  
Sue S. Yom ◽  
Richard L. Bakst
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Primary Therapy ◽  
Target Delineation ◽  
Treatment Regimens ◽  
Adenoid Cystic ◽  
Patient Morbidity ◽  
Frequent Finding ◽  
Lymphovascular Space Invasion

Adenoid cystic carcinoma of the head and neck is an uncommon malignancy that can arise in the major or minor salivary glands. Perineural invasion (PNI) is an extremely frequent finding in cases of adenoid cystic carcinoma (ACC) that can be associated with significant patient morbidity and poor prognosis. By contrast, ACC rarely demonstrates lymphovascular space invasion thereby making PNI the major avenue for metastasis and a driver of treatment rationale and design. Radiotherapy is often utilized post-operatively to improve locoregional control or as a primary therapy in unresectable disease. Here we aim to review the role of radiotherapy in the management of this malignancy with a focus on target delineation and treatment regimens in the definitive, recurrent, and metastatic settings.

scholarly journals The Role of Particle Therapy in Adenoid Cystic Carcinoma and Mucosal Melanoma of the Head and Neck

2021 ◽  
Vol 8 (1) ◽  
pp. 273-284
Author(s):  
Daniel K. Ebner ◽  
Timothy D. Malouff ◽  
Steven J. Frank ◽  
Masashi Koto
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Mucosal Melanoma ◽  
Particle Therapy ◽  
Dose Delivery ◽  
Adenoid Cystic ◽  
Particle Irradiation ◽  
Linear Energy Transfer Radiation ◽  
High Linear Energy Transfer

Abstract Particle irradiation is suitable for resistant histologies owing to a combination of improved dose delivery with potential radiobiologic advantages in high linear energy transfer radiation. Within the head and neck, adenoid cystic carcinoma and mucosal melanoma are two such histologies, being radioresistant and lying closely proximal to critical structures. Here, we review the use of particle irradiation for adenoid cystic carcinoma and mucosal melanoma of the head and neck.

scholarly journals Prognostic Relevance of Thyroid-Hormone-Associated Proteins in Adenoid Cystic Carcinoma of the Head and Neck

2021 ◽  
Vol 11 (12) ◽  
pp. 1352
Author(s):  
Julia Schnoell ◽  
Ulana Kotowski ◽  
Bernhard J. Jank ◽  
Stefan Stoiber ◽  
Elisabeth Gurnhofer ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Adenoid Cystic Carcinoma ◽  
Head And Neck ◽  
Thyroid Hormone Receptor ◽  
Sodium Iodide Symporter ◽  
Protein Levels ◽  
Adenoid Cystic ◽  
Associated Proteins ◽  
Cause Specific Survival

The proteins sodium iodide symporter (NIS), μ-crystallin (CRYM), and thyroid hormone receptor beta (THRB) have been associated with prognosis in various cancer entities. While NIS and THRB may serve as possible therapeutic targets, the role of CRYM in cancer is still unclear. Protein levels of 44 patients with adenoid cystic carcinoma of the head and neck were analyzed using immunohistochemistry and correlated with clinicopathological data and outcome. NIS was positive in 72%, CRYM was positive in 55%, and THRB was positive in 39% of the patients. CRYM-positive adenoid cystic carcinomas were associated with a better cause-specific survival. Thus, our data indicate that CRYM might be a suitable positive prognostic marker in adenoid cystic carcinoma of the head and neck. Furthermore, expression of NIS was present in most patients and therefore evaluation of the use of radioiodine treatment is recommended.

The role of elective neck dissection during salvage surgery in head and neck squamous cell carcinoma

2013 ◽  
Vol 133 (8) ◽  
pp. 886-892 ◽  
Author(s):  
Dong Jin Lee ◽  
Kee Hwan Kwon ◽  
Eun Jae Chung ◽  
Il Seok Park ◽  
Jin Hwan Kim ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Salvage Surgery ◽  
Neck Squamous Cell Carcinoma ◽  
Elective Neck Dissection
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