Oropharyngeal squamous cell carcinoma incidence and mortality trends in the United States, 1973-2013

2017 ◽  
Vol 128 (7) ◽  
pp. 1582-1588 ◽  
Author(s):  
Uchechukwu C. Megwalu ◽  
Davud Sirjani ◽  
Erin E. Devine
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Mortality Trends ◽  
Incidence And Mortality

40-year incidence trends for oropharyngeal squamous cell carcinoma in the United States

Oral Oncology ◽  
2017 ◽  
Vol 74 ◽  
pp. 90-97 ◽  
Author(s):  
Nosayaba Osazuwa-Peters ◽  
Matthew C. Simpson ◽  
Sean T. Massa ◽  
Eric Adjei Boakye ◽  
Jastin L. Antisdel ◽  
...  
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Incidence Trends

scholarly journals Prevalence of Human Papillomavirus in Oropharyngeal Squamous Cell Carcinoma in the United States Across Time

2014 ◽  
Vol 27 (4) ◽  
pp. 462-469 ◽  
Author(s):  
Andrew P. Stein ◽  
Sandeep Saha ◽  
Menggang Yu ◽  
Randall J. Kimple ◽  
Paul F. Lambert
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Oropharyngeal Squamous Cell Carcinoma

scholarly journals Recent Trends in Squamous Cell Carcinoma of the Anus Incidence and Mortality in the United States, 2001–2015

2019 ◽  
Vol 112 (8) ◽  
pp. 829-838 ◽  
Author(s):  
Ashish A Deshmukh ◽  
Ryan Suk ◽  
Meredith S Shiels ◽  
Kalyani Sonawane ◽  
Alan G Nyitray ◽  
...  
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Birth Cohort ◽  
Squamous Cell ◽  
White Women ◽  
Age Groups ◽  
The United States ◽  
Incidence Trends ◽  
Incidence And Mortality

Abstract Background Squamous cell carcinoma of the anus (SCCA) incidence is rising in the United States. Study of incidence trends by stage at diagnosis, age-specific and birth cohort patterns, and trends in mortality could provide evidence for a true increase and etiological clues for the increase in incidence. Methods Using the US Cancer Statistics dataset, we examined trends in SCCA incidence (2001–2015) and mortality (2001–2016) rates. Join-point regression was used to compute annual and average annual percentage change (AAPC). Incidence patterns by 5-year age group and birth cohort were evaluated using incidence rate ratios (IRRs) and age-period-cohort modeling. Results SCCA incidence increased 2.7% per year (95% confidence interval [CI] = 2.1% to 3.3%), with pronounced increases in age groups 50 years and older. Distant-stage SCCA incidence tripled (AAPC = 8.6%, 95% CI = 5.4% to 12.0%, among men and AAPC = 7.5%, 95% CI = 4.8% to 10.2%, among women) and regional-stage SCCA incidence nearly doubled (AAPC = 4.7% for men and women) in both sexes; the AAPC for localized stage was 1.3% (95% CI = 0.6% to 2.0%) in men and 2.3% (95% CI = 1.8% to 2.8%) in women. Compared with adults born circa 1946, recently born black men (born circa 1986) had a nearly fivefold higher risk (IRR = 4.7, 95% CI = 2.1 to 10.2) of SCCA, and the risk doubled among white men (IRR = 2.0, 95% CI = 1.7 to 2.2) and white women (IRR = 2.1, 95% CI = 1.9 to 2.3) born after circa 1960. Anal cancer mortality rates increased 3.1% per year (95% CI = 2.6% to 3.5%) with statistically significant increases in age groups 50 years and older. SCCA incidence-based mortality increased 1.9% annually (95% CI = 0.5% to 3.4%), with a notable (4.9%, 95% CI = 2.4% to 7.3%, per year) rise in adults ages 60–69 years. Conclusion The increase in SCCA incidence, particularly advanced-stage disease, and a similar increase in mortality suggest a true increase in the occurrence of SCCA. Future research and improved prevention are urgently needed to mitigate the increasing disease burden.

Schutz vor Hautkrebs durch Vitamin-A-reiche Ernährung?

2020 ◽  
Vol 52 (01) ◽  
pp. 25-28
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Vitamin A ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Carcinoma Risk

Kim J, Park MK, Li WQ et al. Association of vitamin A intake with cutaneous squamous cell carcinoma risk in the United States. JAMA Dermatol 2019; doi:10.1001/jamadermatol. 2019.1937

All-Cause 30-Day Mortality After Surgical Treatment for Head and Neck Squamous Cell Carcinoma in the United States

2019 ◽  
Vol 42 (7) ◽  
pp. 596-601 ◽  
Author(s):  
Aleksandr R. Bukatko ◽  
Parth B. Patel ◽  
Vindhya Kakarla ◽  
Matthew C. Simpson ◽  
Eric Adjei Boakye ◽  
...  
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Surgical Treatment ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
The United States ◽  
Neck Squamous Cell Carcinoma

scholarly journals Molecular Approach to Cutaneous Squamous Cell Carcinoma: From Pathways to Therapy

2020 ◽  
Vol 21 (4) ◽  
pp. 1211
Author(s):  
Elisabetta Palazzo ◽  
Maria I. Morasso ◽  
Carlo Pincelli
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Molecular Approach

Cutaneous squamous cell carcinoma (cSCC) represents the second most frequent skin cancer, recently showing a rapid increase in incidence worldwide, with around >1 million cases/year in the United States and 2500 deaths [...]

scholarly journals Investigating epidemiologic trends and the geographic distribution of patients with anal squamous cell carcinoma throughout Canada

2020 ◽  
Vol 27 (3) ◽  
Author(s):  
L. Cattelan ◽  
F. M. Ghazawi ◽  
M. Le ◽  
E. Savin ◽  
A. Zubarev ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Anal Cancer ◽  
Squamous Cell ◽  
Demographic Data ◽  
Cancer Registries ◽  
The United States ◽  
Incidence Rates ◽  
Anal Squamous Cell Carcinoma ◽  
Incidence And Mortality

Background Anal cancer is a rare disease, constituting 0.5% of new cancer cases in the United States. The most common subtype is squamous cell carcinoma (scc). Studies in several developed nations have reported on an increasing incidence of anal cancer in recent decades, and various risk factors pertaining to the pathogenesis of the disease have been identified, including infection with the human papillomavirus, tobacco use, and immunosuppression. The epidemiology and distribution of anal scc throughout Canada remain poorly understood, however. Methods Using 3 population-based cancer registries, a retrospective analysis of demographic data across Canada for 1992–2010 was performed. The incidence and mortality for anal scc was examined at the levels of provinces, cities, and the forward  sortation area (FSA) component (first 3 characters) of postal codes. Results During 1992–2010, 3720 individuals were diagnosed with anal scc in Canada; 64% were women. The overall national incidence rate was 6.3 cases per million population per year, with an average age at diagnosis of 60.4 years. The incidence increased over time, with significantly higher incidence rates documented in British Columbia and Nova Scotia (9.3 cases per million population each). Closer examination revealed clustering of cases in various urban centres and self-identified lgbtq communities in Toronto, Montreal, and Vancouver. Discussion This study provides, for the first time, a comprehensive analysis of the burden of anal scc in Canada, identifying susceptible populations and shedding light onto novel avenues of research to lower the incidence of anal cancer throughout the country.

Squamous Cell Carcinoma of the Anal Canal: Utilization and Outcomes of Recommended Treatment in the United States

2008 ◽  
Vol 15 (7) ◽  
pp. 1948-1958 ◽  
Author(s):  
Karl Y. Bilimoria ◽  
David J. Bentrem ◽  
Clifford Y. Ko ◽  
Andrew K. Stewart ◽  
David P. Winchester ◽  
...  
Keyword(s):  
United States ◽  
Squamous Cell Carcinoma ◽  
Anal Canal ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
The United States ◽  
Recommended Treatment
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