scholarly journals Family history of cancer and head and neck cancer survival

2017 ◽  
Vol 127 (8) ◽  
pp. 1816-1820 ◽  
Author(s):  
Kayla R. Getz ◽  
Laura S. Rozek ◽  
Lisa A. Peterson ◽  
Emily L. Bellile ◽  
Jeremy M. G. Taylor ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Family History ◽  
Head And Neck ◽  
Neck Cancer ◽  
Cancer Survival ◽  
Family History Of Cancer ◽  
History Of ◽  
History Of Cancer

scholarly journals Family history of cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium

2009 ◽  
Vol 124 (2) ◽  
pp. 394-401 ◽  
Author(s):  
Eva Negri ◽  
Paolo Boffetta ◽  
Julien Berthiller ◽  
Xavier Castellsague ◽  
Maria Paula Curado ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Family History ◽  
Head And Neck ◽  
Neck Cancer ◽  
Pooled Analysis ◽  
Cancer Epidemiology ◽  
Family History Of Cancer ◽  
History Of ◽  
History Of Cancer

scholarly journals Family History of Cancer and Head and Neck Cancer Risk in a Chinese Population

2015 ◽  
Vol 16 (17) ◽  
pp. 8003-8008 ◽  
Author(s):  
Yu-Hui Jenny Huang ◽  
Yuan-Chin Amy Lee ◽  
Qian Li ◽  
Chien-Jen Chen ◽  
Wan-Lun Hsu ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Family History ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Chinese Population ◽  
Family History Of Cancer ◽  
History Of ◽  
History Of Cancer

scholarly journals The role of family history of Cancer in Oral Cavity Cancer

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Paolo Junior Fantozzi ◽  
Roxanne Bavarian ◽  
Ibon Tamayo ◽  
Marie-Abele Bind ◽  
Sook-Bin Woo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Family History ◽  
Head And Neck ◽  
Personal History ◽  
Oral Leukoplakia ◽  
Family History Of Cancer ◽  
History Of ◽  
History Of Cancer

Abstract Objectives Oral and oropharyngeal squamous cell carcinoma (SCC) is the 10th most common cancer in the United States (8th in males, 13th in females), with an estimated 54,010 new cases expected in 2021, and is primarily associated with smoked tobacco, heavy alcohol consumption, areca nut use and persistent high-risk human papillomavirus (HPV). Family history of cancer (FHC) and family history of head and neck cancer (FHHNC) have been reported to play an important role in the development of OSCC. We aimed to investigate the role of FHC, FHHNC and personal history of cancer in first/second degree-relatives as co-risk factors for oral cancer. Methods This was a retrospective study of patients diagnosed with OSCC at the Division of Oral Medicine and Dentistry at Brigham and Women’s Hospital and at the Division of Head and Neck Oncology at Dana Farber Cancer Institute. Conditional logistic regressions were performed to examine whether OSCC was associated with FHC and FHHNC of FDRs and SDRs, personal history of cancer and secondary risk factors. Results Overall, we did not find an association between FHC, FHHNC and OSCC risk, whereas patients with a cancer history in one of their siblings were 1.6-times more likely to present with an OSCC. When secondary risk factors were considered, patients with a history of oral leukoplakia and dysplasia had a 16-times higher risk of having an OSCC. Conclusions Our study confirmed that a previous history of oral leukoplakia or dysplasia was an independent risk factor for OSCC. A positive family history of cancer in one or more siblings may be an additional risk factor for OSCC.

scholarly journals Risk Prediction Models for Head and Neck Cancer in the US Population From the INHANCE Consortium

2019 ◽  
Vol 189 (4) ◽  
pp. 330-342 ◽  
Author(s):  
Yuan-Chin Amy Lee ◽  
Mohammed Al-Temimi ◽  
Jian Ying ◽  
Joshua Muscat ◽  
Andrew F Olshan ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Family History ◽  
Head And Neck ◽  
Risk Prediction ◽  
Sex Education ◽  
Neck Cancer ◽  
Prediction Models ◽  
Absolute Risk ◽  
Risk Prediction Models ◽  
History Of

Abstract Head and neck cancer (HNC) risk prediction models based on risk factor profiles have not yet been developed. We took advantage of the large database of the International Head and Neck Cancer Epidemiology (INHANCE) Consortium, including 14 US studies from 1981–2010, to develop HNC risk prediction models. Seventy percent of the data were used to develop the risk prediction models; the remaining 30% were used to validate the models. We used competing-risk models to calculate absolute risks. The predictors included age, sex, education, race/ethnicity, alcohol drinking intensity, cigarette smoking duration and intensity, and/or family history of HNC. The 20-year absolute risk of HNC was 7.61% for a 60-year-old woman who smoked more than 20 cigarettes per day for over 20 years, consumed 3 or more alcoholic drinks per day, was a high school graduate, had a family history of HNC, and was non-Hispanic white. The 20-year risk for men with a similar profile was 6.85%. The absolute risks of oropharyngeal and hypopharyngeal cancers were generally lower than those of oral cavity and laryngeal cancers. Statistics for the area under the receiver operating characteristic curve (AUC) were 0.70 or higher, except for oropharyngeal cancer in men. This HNC risk prediction model may be useful in promoting healthier behaviors such as smoking cessation or in aiding persons with a family history of HNC to evaluate their risks.

Head and neck cancer awareness: a survey of young people in international communities

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Kehinde Kazeem Kanmodi ◽  
Nneamaka Nnebedum ◽  
Mayowa Bello ◽  
Miracle Adesina ◽  
Omotayo Francis Fagbule ◽  
...  
Keyword(s):  
Risk Factors ◽  
Head And Neck Cancer ◽  
Family History ◽  
Young People ◽  
Head And Neck ◽  
Neck Cancer ◽  
Significant Proportion ◽  
Risky Behaviors ◽  
Cancer Awareness ◽  
History Of

Abstract Head and neck cancer (HNC) is killing young people yearly. The knowledge of HNC risk factors and its symptoms among this population group may go a long way in HNC prevention among them. This study aims to: determine the level of awareness of HNC; determine the prevalence of HNC risk factors; and explore the knowledge of HNC risk factors, HNC symptoms, as well as family history of HNC among youth in the international communities (with focus on the Canadian and Nigerian youth). Methods A sample of 801 youth were surveyed using an e-questionnaire. The questionnaire obtained information from each participant about their: socio-demographic information; knowledge of HNC, its risk factors, and its manifestations; and family history of HNC. Data obtained from the participants were analyzed using the Statistical Analysis Software (SAS Version 9.4 for Windows). Results The majority (73%) of the surveyed youth (n=801) were residing in Nigeria, seven-tenths of them were between the age 18 and 24 years, and 53% were females. Less than 10% had a history of smoking, 7% were active smokers, and 24% had history of oral sex (of which 57% (108/109) of them had a lifetime history of more than one oral sexual partner). Around half (51%) of the participants had never heard of HNC before. Only 4% knew of a family member who had suffered/is suffering from HNC. Half of the participants were not sure whether HNC can manifest without initial complaint, pain, or symptoms. Only 9% of the participants erroneously believed that HNC is a contagious disease. Comparative analyses among subgroups revealed that a higher proportion of those participants who were: from Canada; young adults; and males generally knew about HNC when compared with the proportions recorded among those in the adolescents; females, and Nigerian participants’ categories. Lastly, 76% of the participants showed interest in knowing more about HNC. Conclusion The majority of the surveyed youth demonstrated poor knowledge of HNC. Also, a significant proportion of them are at risk of developing HNC disease in future, if they keep indulging in HNC risky behaviors. There exists the need to conduct community health education programs on HNC among youth in these surveyed communities.

scholarly journals Family history of cancer in first degree relatives and risk of cancer of unknown primary

2021 ◽  
Author(s):  
Alexander L. R. Grewcock ◽  
Karlijn E. P. E. Hermans ◽  
Matty P. Weijenberg ◽  
Piet A. Brandt ◽  
Caroline Loef ◽  
...  
Keyword(s):  
Family History ◽  
Cancer Of Unknown Primary ◽  
Unknown Primary ◽  
Family History Of Cancer ◽  
First Degree Relatives ◽  
History Of ◽  
Risk Of Cancer ◽  
History Of Cancer
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