Functional outcomes after different types of transoral supraglottic laryngectomy

2015 ◽  
Vol 126 (5) ◽  
pp. 1131-1135 ◽  
Author(s):  
Cesare Piazza ◽  
Diego Barbieri ◽  
Francesca Del Bon ◽  
Paola Grazioli ◽  
Pietro Perotti ◽  
...  
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jung Il Lee ◽  
Anagha A. Gurjar ◽  
M. A. Hassan Talukder ◽  
Andrew Rodenhouse ◽  
Kristen Manto ◽  
...  

AbstractPeripheral nerve transection is associated with permanent functional deficit even after advanced microsurgical repair. While it is difficult to investigate the reasons of poor functional outcomes of microsurgical repairs in humans, we developed a novel pre-clinical nerve transection method that allows reliable evaluation of nerve regeneration, neural angiogenesis, muscle atrophy, and functional recovery. Adult male C57BL/6 mice were randomly assigned to four different types of sciatic nerve transection: Simple Transection (ST), Simple Transection & Glue (TG), Stepwise Transection and Sutures (SU), and Stepwise Transection and Glue (STG). Mice were followed for 28 days for sciatic function index (SFI), and sciatic nerves and hind limb muscles were harvested for histomorphological and cellular analyses. Immunohistochemistry revealed more directional nerve fiber growth in SU and STG groups compared with ST and TG groups. Compared to ST and TG groups, optimal neural vessel density and branching index in SU and STG groups were associated with significantly decreased muscle atrophy, increased myofiber diameter, and improved SFI. In conclusion, our novel STG method represents an easily reproducible and reliable model with close resemblance to the pathophysiological characteristics of SU model, and this can be easily reproduced by any lab.


2017 ◽  
Vol 52 (4) ◽  
pp. 563-568 ◽  
Author(s):  
Kristiina Kyrklund ◽  
Mikko P. Pakarinen ◽  
Risto J. Rintala

Medicine ◽  
2020 ◽  
Vol 99 (19) ◽  
pp. e19830
Author(s):  
Hongwei Chen ◽  
Jinqing Wu ◽  
Pinyi Zhao ◽  
Lijun Wu ◽  
Chao Guo

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 6053-6053
Author(s):  
Philippe Ceruse ◽  
Benjamin Lallemant ◽  
Karine Aubry ◽  
Sylvain Morinieres ◽  
Sebastien Vergez ◽  
...  

6053 Background: Transoral, minimally invasive organ preservation surgeries are being increasingly used for laryngopharyngeal carcinomas to avoid the toxicities of combined chemotherapy and radiation therapy regimens. This study investigates the efficiency, safety, and functional outcomes of transoral robot assisted surgery (TORAS) for supraglottic laryngectomy. Methods: Experience of TORA supraglottic laryngectomy for patients with supraglottic carcinomas is presented in a multicentric study of a case series with planned data collection between 2009 and 2012. Results: Eighty-six of 262 patients underwent TORA supraglottic laryngectomy for supraglottic carcinomas. Thirty-three percent of patients were started an oral diet within 24 hours. For 77% of the other patients, the median use of a feeding tube was 8 days (0-10 months). Nine percent of them had a definitive percutaneous gastrostomy feeding. For 87% of patients no tracheotomy was performed, for 23% of the others patients, the median use of tracheotomy was 8 days, 3% of them had a definitive tracheotomy. Aspiration was observed in 22% of the patients in the postoperative course and was responsible for the death of one patient. Sixteen percent of the patients had a postoperative bleeding. Fifty percent of the patients received adjuvant radiation therapy based on pathology results. Conclusions: TORA supraglottic laryngectomy is a safe procedure with good functional outcomes and fast recovery but adverse events are possible. Consequently this technique needs a good selection of the patients to reduce the risk of postoperative complications.


2020 ◽  
Author(s):  
Stéphane Hans ◽  
Younès Chekkoury‐Idrissi ◽  
Marta P. Circiu ◽  
Léa Distinguin ◽  
Lise Crevier‐Buchman ◽  
...  

Author(s):  
Jonathan Smallwood ◽  
Daniel Margulies ◽  
Boris C. Bernhardt ◽  
Elizabeth Jefferies

Spontaneous thoughts come in a large variety of different forms, varying in their experiential content as well as the functional outcomes with which they are associated. This chapter describes a component process architecture for spontaneous thought in which different types of experience arise through the combinations of different underlying neurocognitive processes. These underlying elements of cognition are not specific to spontaneous thought, since many, if not all, of these neurocognitive processes can be engaged when participants perform an externally directed task. We consider neurocognitive evidence that shows how this component process architecture provides explanatory value for accounts of spontaneous thought since it provides a mechanism that captures both the complex variety of spontaneous experiences that characterize the human condition, as well as the different functional outcomes that these different experiences are associated with.


Author(s):  
G Scotta ◽  
A Allam ◽  
P A Dimitriadis ◽  
K Wright ◽  
M Yardley ◽  
...  

Abstract Objective This study aimed to evaluate surgical and functional outcomes, in a tertiary referral centre, of two different types of semi-implantable transcutaneous bone conduction devices. Method This study involved prospective data collection and review of patients implanted between November 2014 and December 2016. Glasgow Hearing Aid Inventory (Glasgow Hearing Aid Benefit Profile or Glasgow Hearing Aid Difference Profile) and Client Oriented Scale of Improvement were completed where appropriate. Surgical and audiological outcomes were recorded in the surgical notes. Results Glasgow Hearing Aid Difference Profile and Glasgow Hearing Aid Benefit Profile showed similar mean score in the active and the passive transcutaneous bone conduction devices. Client Oriented Scale of Improvement showed improvements in listening situations. Post-operative speech reception threshold showed better mean threshold in the active transcutaneous bone conduction devices group when compared with the passive transcutaneous bone conduction devices group. No device failures or surgical complications existed in either group, with the surgical time being less in the passive transcutaneous bone conduction devices group. Conclusion Both devices are reliable semi-implantable transcutaneous bone conduction devices with excellent surgical and functional outcomes and patient satisfaction. Overall surgical time was much less in the passive transcutaneous bone conduction devices group with no necessity for pre-planning. This is much easier to remove with the possibility of conversion to other devices in the manufacturer’s portfolio and wide-ranging wireless accessories. Further studies are needed to assess the longer-term results in a bigger population.


2004 ◽  
Vol 425 ◽  
pp. 64-71 ◽  
Author(s):  
Roger Cornwall ◽  
Marvin S Gilbert ◽  
Kenneth J Koval ◽  
Elton Strauss ◽  
Albert L Siu

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