Long-term effects of repetitive transcranial magnetic stimulation in unilateral tinnitus

2014 ◽  
Vol 124 (9) ◽  
pp. 2155-2160 ◽  
Author(s):  
Hyun J. Kim ◽  
Deog Y. Kim ◽  
Hyo I. Kim ◽  
Hee S. Oh ◽  
Nam S. Sim ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Long Term Effects

Effectiveness of Repetitive Transcranial Magnetic Stimulation for Chronic Tinnitus

2012 ◽  
Vol 147 (5) ◽  
pp. 817-825 ◽  
Author(s):  
Zhe Peng ◽  
Xiu-Qi Chen ◽  
Shu-Sheng Gong
Keyword(s):  
Systematic Review ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Chronic Tinnitus ◽  
Hearing Level ◽  
Long Term Effects ◽  
Short Term

Objective This systematic review aimed to assess the effectiveness of repetitive transcranial magnetic stimulation (rTMS) treatment for chronic tinnitus. Data Sources Relevant electronic databases and a reference list of articles published up to January 2012 were searched. Randomized controlled clinical trials of all types of rTMS treatment for patients with chronic tinnitus were included. Review Methods A literature search was conducted with structured criteria to select studies evaluated for systematic review. Results Five trials (160 participants) were included in this review. Repetitive transcranial magnetic stimulation treatment showed benefits in the short term, but the long-term effects are questionable. The Tinnitus Handicap Inventory (THI) and the visual analog scale (VAS) were the major assessment methods used. After active TMS stimulation, the reduction in the THI total score and VAS was significant compared with baseline at the first time point assessed and in the short term (2 weeks and 4 weeks). The longest follow-up time was 26 weeks after treatment, and the shortest follow-up time was 2 weeks. No severe side effects were reported from the use of rTMS. Differences in age, hearing level, duration of tinnitus of the included patients, and the condition of sham treatment may influence the effect. Conclusion Repetitive transcranial magnetic stimulation could be a new therapeutic tool for the treatment of chronic tinnitus, and thus far we have not been able to demonstrate any substantial risk from rTMS treatment. However, the long-term effects of rTMS treatment for tinnitus are not clear and will require further study.

scholarly journals An updated meta-analysis: repetitive transcranial magnetic stimulation for treating tinnitus

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199954
Author(s):  
Lu Yin ◽  
Xiao Chen ◽  
Xingang Lu ◽  
Yun An ◽  
Tao Zhang ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Future Research ◽  
Long Term Effects ◽  
Tinnitus Questionnaire ◽  
Eligibility Criteria ◽  
Cochrane Database

Objective To undertake an updated meta-analysis to obtain more evidence from randomized controlled trials (RCTs) to assess the effect of repetitive transcranial magnetic stimulation (rTMS) for the treatment of tinnitus. Methods PubMed®, Embase®, Web of Science, Cochrane Database of Systematic Reviews, CBM, CNKI and Wanfang were searched for RCTs from inception up to March 2020. Studies meeting the eligibility criteria were included in the meta-analysis. The mean difference was calculated and the effect size was evaluated using a Z test. Results The analysis included 12 randomized sham-controlled clinical trials with a total of 717 participants. Active rTMS was superior to sham rTMS in terms of the short-term and long-term effects (6 months) on the tinnitus handicap inventory scores, but an immediate effect was not significant. There was no significant immediate effect on the tinnitus questionnaire (TQ) and Beck depression inventory (BDI) scores. Conclusions This meta-analysis demonstrated that rTMS improved tinnitus-related symptoms, but the TQ and BDI scores demonstrated little immediate benefit. Future research should be undertaken on large samples in multi-centre settings with longer follow-up durations.

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