Long-term outcomes of surgery followed by radiation therapy for minor salivary gland carcinomas

2013 ◽  
Vol 123 (11) ◽  
pp. 2675-2680 ◽  
Author(s):  
Youssef H. Zeidan ◽  
David B. Shultz ◽  
James D. Murphy ◽  
Yi An ◽  
Cato Chan ◽  
...  
2006 ◽  
Vol 66 (4) ◽  
pp. 1044-1050 ◽  
Author(s):  
Allen M. Chen ◽  
M. Kara Bucci ◽  
Jeanne M. Quivey ◽  
Joaquin Garcia ◽  
David W. Eisele ◽  
...  

2019 ◽  
Author(s):  
Anna Bistline ◽  
Andrew Song ◽  
James Evans ◽  
Christopher Farrell ◽  
David Andrews ◽  
...  

2010 ◽  
Vol 6 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Kyung Sun Song ◽  
Ji Hoon Phi ◽  
Byung-Kyu Cho ◽  
Kyu-Chang Wang ◽  
Ji Yeoun Lee ◽  
...  

Object Glioblastoma is the most common primary malignant brain tumor; however, glioblastoma in children is less common than in adults, and little is known about its clinical outcome in children. The authors evaluated the long-term outcome of glioblastoma in children. Methods Twenty-seven children were confirmed to have harbored a glioblastoma between 1985 and 2007. The clinical features and treatment outcomes were reviewed retrospectively. All patients underwent resection; complete resection was performed in 12 patients (44%), subtotal resection in 12 patients (44%), and biopsy in 3 patients (11%). Twenty-four patients (89%) had radiation therapy, and 14 (52%) patients received chemotherapy plus radiation therapy. Among the latter, 5 patients had radiation therapy concurrent with temozolomide chemotherapy. Four patients with small-size recurrent glioblastoma received stereotactic radiosurgery. Results The median overall survival (OS) was 43 months, and the median progression-free survival was 12 months. The OS rate was 67% at 1 year, 52% at 2 years, and 40% at 5 years. The median OS was significantly associated with tumor location (52 months for superficially located tumors vs 7 months for deeply located tumors; p = 0.017) and extent of removal (106 months for completely resected tumors vs 11 months for incompletely resected tumors; p < 0.0001). Conclusions The prognosis of glioblastoma is better in children than in adults. Radical resection followed by concurrent chemoradiation therapy may be the initial treatment of choice.


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