Effects of basic fibroblast growth factor-2 and hyaluronic acid on tracheal wound healing

2009 ◽  
Vol 119 (4) ◽  
pp. 734-739 ◽  
Author(s):  
Noah P. Parker ◽  
Samual S. Bailey ◽  
David L. Walner
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 2 ◽  
Fibroblast Growth

scholarly journals Preparation of Foam Dressings Based on Gelatin, Hyaluronic Acid, and Carboxymethyl Chitosan Containing Fibroblast Growth Factor-7 for Dermal Regeneration

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3279
Author(s):  
Longhao Jin ◽  
Sun-Jung Yoon ◽  
Dae Hoon Lee ◽  
Yun Chang Pyun ◽  
Woo Youp Kim ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Wound Healing ◽  
Hyaluronic Acid ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Wound Dressing ◽  
Transmission Rate ◽  
Carboxymethyl Chitosan ◽  
Amide Bond ◽  
Fibroblast Growth

Wound recovery close to the function of the native skin is the goal of wound healing. In this study, we prepared foam dressings (FDs; 2-GHC-FD-1–9, 5-GHC-FD-1–9, and 10-GHC-FD-1–9) composed of various concentrations of gelatin, hyaluronic acid, and carboxymethyl chitosan, which are chemically interconnected through amide bond formation, for evaluating wound healing. Tensile and cell proliferation tests showed that 2-GHC-FD-1–9 are suitable for wound dressing. For further evaluation, three types of FDs, 2-GHC-FD-1, 2-GHC-FD-4, and 2-GHC-FD-8 were chosen. The results of animal intradermal reactivity, water vapor transmission rate, and absorption rate of the three FDs indicated that 2-GHC-FD-8 is the most appropriate scaffold for wound healing. For wound healing acceleration, various concentrations of fibroblast growth factor-7 (FGF-7) was soaked in 2-GHC-FD-8 (2-GHC-FD-8/F1-6) and evaluated by using scanning electron microscopy, cell proliferation, release behavior, and in vivo animal tests. The FDs showed interconnected porous structures, increased cell proliferation until 8.0 × 10−11 M, controlled release with initial burst within 1 h, and sustained release for 48 h. The results of the animal test showed an appropriate concentration of FGF-7 for wound healing. In addition, 2-GHC-FD-8 is a suitable scaffold for wound healing. Therefore, we suggest that 2-GHC-FD-8/F3 is a useful wound dressing for accelerating wound healing.

Application of Basic Fibroblast Growth Factor May Reverse Diabetic Wound Healing Impairment

1993 ◽  
Vol 31 (4) ◽  
pp. 331-334 ◽  
Author(s):  
Linda G. Phillips ◽  
Kay M. Abdullah ◽  
Peter D. Geldner ◽  
Stewart Dobbins ◽  
Francis Ko ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Healing Impairment

Structure-guided design, generation, and biofunction of PEGylated fibroblast growth factor 2 variants for wound healing

Nanoscale ◽  
2020 ◽  
Vol 12 (35) ◽  
pp. 18200-18213
Author(s):  
Jian Sun ◽  
Jiamin Wu ◽  
Hui Jin ◽  
Te Ying ◽  
Wei Jin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 2 ◽  
Fibroblast Growth ◽  
Skin Repair ◽  
Improved Stability ◽  
Design Generation

Structure-guided PEGylation of fibroblast growth factor 2 with improved stability and bioactivity for skin repair.

scholarly journals The Effect of Control-released Basic Fibroblast Growth Factor in Wound Healing

2013 ◽  
Vol 1 (6) ◽  
pp. e44 ◽  
Author(s):  
Shigeru Matsumoto ◽  
Rica Tanaka ◽  
Kayoko Okada ◽  
Kayo Arita ◽  
Hiko Hyakusoku ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Fibroblast Growth
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