Oxidation studies with peroxomonophosphoric acid. II. A kinetic and mechanistic study of dimethyl sulfoxide oxidation in acid and alkaline media

1980 ◽  
Vol 12 (7) ◽  
pp. 491-499 ◽  
Author(s):  
G. P. Panigrahi ◽  
Radhasyam Panda
Keyword(s):  
Dimethyl Sulfoxide ◽  
Alkaline Media ◽  
Mechanistic Study

scholarly journals Kinetics and Mechanistic Study of Hydrolysis of Adenosine Monophosphate Disodium Salt (AMPNa2) in Acidic and Alkaline Media

2019 ◽  
Vol 17 (1) ◽  
pp. 544-556
Author(s):  
Yoke-Leng Sim ◽  
Beljit Kaur
Keyword(s):  
Rate Constant ◽  
Adenosine Monophosphate ◽  
Disodium Salt ◽  
Second Order ◽  
Information Storage ◽  
Alkaline Media ◽  
Basic Medium ◽  
Mechanistic Study ◽  
Phosphate Ester ◽  
Hydrolysis Of

AbstractPhosphate ester hydrolysis is essential in signal transduction, energy storage and production, information storage and DNA repair. In this investigation, hydrolysis of adenosine monophosphate disodium salt (AMPNa2) was carried out in acidic, neutral and alkaline conditions of pH ranging between 0.30-12.71 at 60°C. The reaction was monitored spectrophotometrically. The rate ranged between (1.20 ± 0.10) × 10-7 s-1 to (4.44 ± 0.05) × 10-6 s-1 at [NaOH] from 0.0008 M to 1.00M recorded a second-order base-catalyzed rate constant, kOH as 4.32 × 10-6 M-1 s-1. In acidic conditions, the rate ranged between (1.32 ± 0.06) × 10-7 s-1 to (1.67 ± 0.10) × 10-6 s-1 at [HCl] from 0.01 M to 1.00 M. Second-order acid-catalyzed rate constant, kH obtained was 1.62 × 10-6 M-1 s-1. Rate of reaction for neutral region, k0 was obtained from graphical method to be 10-7 s-1. Mechanisms were proposed to involve P-O bond cleavage in basic medium while competition between P-O bond and N-glycosidic cleavage was observed in acidic medium. In conclusion, this study has provided comprehensive information on the kinetic parameters and mechanism of cleavage of AMPNa2 which mimicked natural AMP cleavage and the action of enzymes that facilitate its cleavage.

scholarly journals The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos: a mechanistic study

Theranostics ◽  
2017 ◽  
Vol 7 (19) ◽  
pp. 4735-4752 ◽  
Author(s):  
Min-Hee Kang ◽  
Joydeep Das ◽  
Sangiliyandi Gurunathan ◽  
Hwan-Woo Park ◽  
Hyuk Song ◽  
...  
Keyword(s):  
Dimethyl Sulfoxide ◽  
Preimplantation Embryos ◽  
Mechanistic Study ◽  
Cytotoxic Effects

The reduction of CrVI to CrIII by the α and β anomers of d-glucose in dimethyl sulfoxide. A comparative kinetic and mechanistic study

2000 ◽  
Vol 324 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Sandra Signorella ◽  
Rubén Lafarga ◽  
Verónica Daier ◽  
Luis F. Sala
Keyword(s):  
Dimethyl Sulfoxide ◽  
Mechanistic Study

Kinetic and mechanistic study of the X and XO (X = Cl, Br) reactions with dimethyl sulfoxide

2003 ◽  
Vol 5 (13) ◽  
pp. 2828-2835 ◽  
Author(s):  
Véronique Riffault ◽  
Yuri Bedjanian ◽  
Georges Le Bras
Keyword(s):  
Dimethyl Sulfoxide ◽  
Mechanistic Study

Kinetic and mechanistic study of methanol oxidation on a Pt(111) surface in alkaline media

1996 ◽  
Vol 418 (1-2) ◽  
pp. 9-20 ◽  
Author(s):  
A.V. Tripković ◽  
K.Dj. Popović ◽  
J.D. Momčilović ◽  
D.M. Draić
Keyword(s):  
Methanol Oxidation ◽  
Alkaline Media ◽  
Mechanistic Study
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