Time Interval Measurements of the Ductus Venosus During the Early Second Trimester of Pregnancy: Reference Ranges and Clinical Application

2017 ◽  
Vol 37 (3) ◽  
pp. 745-753 ◽  
Author(s):  
Manaphat Suksai ◽  
Chitkasaem Suwanrath ◽  
Ounjai Kor-anantakul ◽  
Alan Geater
Keyword(s):  
Clinical Application ◽  
Ductus Venosus ◽  
Time Interval ◽  
Reference Ranges ◽  
Second Trimester

Agenesis of ductus venosus in sequential first and second trimester screening

2014 ◽  
Vol 34 (11) ◽  
pp. 1099-1105 ◽  
Author(s):  
D. G. Iliescu ◽  
M. L. Cara ◽  
S. Tudorache ◽  
P. Antsaklis ◽  
L. V. Novac ◽  
...  
Keyword(s):  
Ductus Venosus ◽  
Second Trimester ◽  
Second Trimester Screening ◽  
Trimester Screening

Reference ranges for time-related analysis of ductus venosus flow velocity waveforms in singleton pregnancies

2012 ◽  
Vol 32 (8) ◽  
pp. 803-809 ◽  
Author(s):  
Kayoko Nakagawa ◽  
Daisuke Tachibana ◽  
Hiroyuki Nobeyama ◽  
Mitsuru Fukui ◽  
Toshiyuki Sumi ◽  
...  
Keyword(s):  
Flow Velocity ◽  
Ductus Venosus ◽  
Reference Ranges ◽  
Singleton Pregnancies

scholarly journals Hyperthyroidism During Pregnancy: Etiology, Diagnosis and Management

2005 ◽  
Vol 1 (1) ◽  
pp. 97-104
Author(s):  
John H Lazarus
Keyword(s):  
Radioiodine Therapy ◽  
Hyperemesis Gravidarum ◽  
Thyroid Stimulating Hormone ◽  
Postpartum Women ◽  
Reference Ranges ◽  
Second Trimester ◽  
Autoimmune Thyroid ◽  
Mother And Child ◽  
Neonatal Hyperthyroidism ◽  
In Pregnancy

Pregnancy has marked effects on thyroid physiology and autoimmune thyroid disease tends to ameliorate through gestation due to the general immunosuppression seen in pregnancy. There is a need for trimester-specific thyroid hormone reference ranges. Hyperthyroidism in pregnancy – usually due to Graves' disease – is not common but, if the patient is compliant, a good outcome can be expected for both mother and child if treatment with anti-thyroid drugs (propylthiouracil is preferred) is instituted. Thyroid-stimulating hormone receptor antibody should be measured at 36 weeks in such patients in order to predict the possibility of neonatal hyperthyroidism. Transient gestational hyperthyroidism is often associated with hyperemesis gravidarum and thyroid function should be checked in patients severely affected by this condition. Radioiodine therapy is contraindicated in pregnancy but thyroid surgery may be performed safely in the second trimester. Autoimmune thyroiditis and Graves’ hyperthyroidism occur quite commonly in postpartum women.

scholarly journals Reference Values of D-Dimers and Fibrinogen in the Course of Physiological Pregnancy: the Potential Impact of Selected Risk Factors—A Pilot Study

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Aldona Siennicka ◽  
Magdalena Kłysz ◽  
Kornel Chełstowski ◽  
Aleksandra Tabaczniuk ◽  
Zuzanna Marcinowska ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gestational Diabetes ◽  
Reference Values ◽  
Venous Blood ◽  
Fibrinogen Concentration ◽  
Reference Ranges ◽  
Second Trimester ◽  
Increase Risk ◽  
Potential Impact ◽  
D Dimer

Pregnancy predisposes to thrombotic hemostasis, reflected in the laboratory as, e.g., increased levels of D-Dimers and fibrinogen, but in physiological pregnancy, the risk of venous thrombosis does not increase. Risk may increase if gestational diabetes mellitus (GDM) or nicotinism coexists. Study aims were to determine reference values ​​for D-Dimers and fibrinogen concentrations in each trimester of pregnancy, corrected for GDM and nicotinism. Subjects and Methods. The study involved 71 pregnant women aged 25-44 y. Venous blood was collected three times: in the first (11-14 weeks), second (20-22 weeks), and third (30-31 weeks) trimesters. D-Dimer concentrations were determined by an enzyme-linked fluorescence assay, fibrinogen concentrations by a coagulation method according to Clauss. Results. Significant increases in D-Dimers and fibrinogen concentrations were observed, increasing with successive trimesters (p ANOVA<0.0001). Furthermore, a positive correlation between D-Dimers and fibrinogen was detected in the second trimester of pregnancy (r=0.475; p<0.0001). In addition, a significantly higher fibrinogen concentration was found in women with GDM compared to without GDM (p=0.0449). Reference ranges for D-Dimers were established, in trimester order, as follows: 167-721 ng/mL, 298-1653 ng/mL, and 483-2256 ng/mL. After adjusting for risk factors, significantly higher D-Dimer values ​​(mainly second and third trimesters) were obtained: 165-638 ng/mL, 282-3474 ng/mL, and 483-4486 ng/mL, respectively. Reference ranges for fibrinogen were, in trimester order, 2.60-6.56 g/L, 3.40-8.53 g/L, and 3.63-9.14 g/L and, after adjustment for risk factors, 3.34-6.73 g/L, 3.40-8.84 g/L, and 3.12-9.91 g/L. Conclusions. We conclude that the increase in D-Dimers and fibrinogen levels in women with physiological pregnancy was compounded by gestational diabetes (GDM) and nicotinism. Therefore, D-Dimers and fibrinogen pregnancy reference values require correction for these risk factors.

Second-Trimester Ductus Venosus Measurement and Adverse Perinatal Outcome in Fetuses With Congenital Heart Disease

2006 ◽  
Vol 25 (8) ◽  
pp. 979-982 ◽  
Author(s):  
Katherine Bianco ◽  
Maria Small ◽  
Svena Julien ◽  
Trace Kershaw ◽  
Maaike Michon ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Perinatal Outcome ◽  
Congenital Heart ◽  
Ductus Venosus ◽  
Second Trimester ◽  
Adverse Perinatal Outcome

Reference Ranges for Ductus Venosus Velocity Ratios in Pregnancies With Normal Outcomes

2014 ◽  
Vol 33 (2) ◽  
pp. 329-336 ◽  
Author(s):  
Ozhan M. Turan ◽  
Sifa Turan ◽  
Laura Sanapo ◽  
Arne Wilruth ◽  
Christoph Berg ◽  
...  
Keyword(s):  
Ductus Venosus ◽  
Reference Ranges

scholarly journals Reference ranges for the flow velocities and the indices of the ductus venosus in low-risk pregnancies

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Cemil Gürses ◽  
Burak Karadağ ◽  
Onur Erol ◽  
Bekir Sıtkı İsenlik ◽  
Ceyda Karadağ
Keyword(s):  
Low Risk ◽  
Ductus Venosus ◽  
Reference Ranges ◽  
Flow Velocities

scholarly journals Reference values for fetal Doppler-based cardiocirculatory indices in monochorionic-diamniotic twin pregnancy

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Thananan Chongsomboonsuk ◽  
Nisarat Phithakwatchara ◽  
Katika Nawapun ◽  
Sommai Viboonchart ◽  
Suparat Jaingam ◽  
...  
Keyword(s):  
Reference Values ◽  
Twin Pregnancy ◽  
Peak Systolic Velocity ◽  
Ductus Venosus ◽  
Diastolic Filling ◽  
Specific Reference ◽  
Reference Ranges ◽  
Cross Sectional ◽  
Filling Time ◽  
Doppler Indices

Abstract Background Placental anastomoses in monochorionic diamniotic (MCDA) twin pregnancy have a major impact on fetal circulation. This study was designed to define reference ranges of cardiac and vascular Doppler indices in MCDA twin pregnancies. Methods This cross-sectional study included 442 uncomplicated MCDA twin fetuses undergoing Doppler ultrasonography at 18–35 weeks of gestation. Left and right myocardial performance index (LV-MPI, RV-MPI), E/A ratio of atrioventricular valves, pulsatility indices of umbilical artery, middle cerebral artery (MCA), and ductus venosus (DV), cerebroplacental ratio, peak systolic velocity of MCA, S/a ratio of DV, and early diastolic filling time of ductus venosus (DV-E) were evaluated under standardized settings. The equation models between Doppler indices and gestational age (GA) were fitted. After adjustment for GA, the correlations between MPI and fetal heart rate (FHR), and between MPI and DV indices were analyzed. Results Estimated centiles of Doppler indices were derived as a function of GA, being distinct in values from those of singletons. There was no correlation between GA-adjusted MPI and FHR. DV-E was inversely related to LV-MPI. Conclusions MCDA twins showed significant changes in some Doppler indices throughout gestation with quantitative differences from singletons, emphasizing the importance of MC twin-specific reference values for clinical application. Further adjustment of MPI for FHR was unnecessary. DV-E is a vascular index indirectly representing fetal diastolic function.

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