Injector-internal thermal desorption from edible oils. Part 1: Visual experiments on sample deposition on the liner wall

2005 ◽  
Vol 28 (13) ◽  
pp. 1550-1557 ◽  
Author(s):  
Maurus Biedermann ◽  
Katell Fiselier ◽  
Koni Grob
Keyword(s):  
Thermal Desorption ◽  
Edible Oils ◽  
Sample Deposition

scholarly journals Coupling Laser Diode Thermal Desorption with Acoustic Sample Deposition to Improve Throughput of Mass Spectrometry–Based Screening

2015 ◽  
Vol 21 (2) ◽  
pp. 165-175 ◽  
Author(s):  
Zuzana Haarhoff ◽  
Andrew Wagner ◽  
Pierre Picard ◽  
Dieter M. Drexler ◽  
Tatyana Zvyaga ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Thermal Desorption ◽  
Laser Diode ◽  
High Throughput Screening ◽  
Solid Phase ◽  
Atmospheric Pressure Chemical Ionization ◽  
Label Free ◽  
Metabolite Formation ◽  
Cyp Inhibition ◽  
Sample Deposition

The move toward label-free screening in drug discovery has increased the demand for mass spectrometry (MS)–based analysis. Here we investigated the approach of coupling acoustic sample deposition (ASD) with laser diode thermal desorption (LDTD)–tandem mass spectrometry (MS/MS). We assessed its use in a cytochrome P450 (CYP) inhibition assay, where a decrease in metabolite formation signifies CYP inhibition. Metabolite levels for 3 CYP isoforms were measured as CYP3A4-1′-OH-midazolam, CYP2D6-dextrorphan, and CYP2C9-4′-OH-diclofenac. After incubation, samples (100 nL) were acoustically deposited onto a stainless steel 384-LazWell plate, then desorbed by an infrared laser directly from the plate surface into the gas phase, ionized by atmospheric pressure chemical ionization (APCI), and analyzed by MS/MS. Using this method, we achieved a sample analysis speed of 2.14 s/well, with bioanalytical performance comparable to the current online solid-phase extraction (SPE)–based MS method. An even faster readout speed was achieved when postreaction sample multiplexing was applied, where three reaction samples, one for each CYP, were transferred into the same well of the LazWell plate. In summary, LDTD coupled with acoustic sample deposition and multiplexing significantly decreased analysis time to 0.7 s/sample, making this MS-based approach feasible to support high-throughput screening (HTS) assays.

Gas chromatography-mass spectrometry using microvial insert thermal desorption for the determination of BTEX in edible oils

RSC Advances ◽  
2016 ◽  
Vol 6 (25) ◽  
pp. 20886-20891 ◽  
Author(s):  
Juan Ignacio Cacho ◽  
Natalia Campillo ◽  
Pilar Viñas ◽  
Manuel Hernández-Córdoba
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Thermal Desorption ◽  
Analytical Procedure ◽  
Edible Oils ◽  
Gas Chromatography Mass Spectrometry ◽  
Sample Handling ◽  
Chromatography Mass Spectrometry ◽  
Minimum Sample

A rapid analytical procedure for BTEX determination involving minimum sample handling.

Biodiesel production from non-edible oils: A review

2020 ◽  
pp. 149-159
Author(s):  
Jatinder Kataria ◽  
Saroj Kumar Mohapatra ◽  
Amit Pal
Keyword(s):  
Environmental Impact ◽  
Energy Demand ◽  
Fossil Fuels ◽  
World Wide ◽  
Edible Oils ◽  
Control Measure ◽  
Biodiesel Production ◽  
Pollution Level ◽  
Animal Fats ◽  
The World

The limited fossil reserves, spiraling price and environmental impact due to usage of fossil fuels leads the world wide researchers’ interest in using alternative renewable and environment safe fuels that can meet the energy demand. Biodiesel is an emerging renewable alternative fuel to conventional diesel which can be produced from both edible and non-edible oils, animal fats, algae etc. The society is in dire need of using renewable fuels as an immediate control measure to mitigate the pollution level. In this work an attempt is made to review the requisite and access the capability of the biodiesel in improving the environmental degradation.

In-pile thermal desorption of PAHs, PCBs and dioxins/furans in soil and sediment

2006 ◽  
Vol 14 (2) ◽  
pp. 620-624 ◽  
Author(s):  
Ralph S. Baker ◽  
John LaChance ◽  
Gorm Heron
Keyword(s):  
Thermal Desorption ◽  
Soil And Sediment
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