scholarly journals Prognostic utility of albumin‐bilirubin grade for short‐ and long‐term outcomes following hepatic resection for intrahepatic cholangiocarcinoma: A multi‐institutional analysis of 706 patients

2019 ◽  
Author(s):  
Diamantis I. Tsilimigras ◽  
J. Madison Hyer ◽  
Dimitrios Moris ◽  
Kota Sahara ◽  
Fabio Bagante ◽  
...  
Keyword(s):  
Hepatic Resection ◽  
Intrahepatic Cholangiocarcinoma ◽  
Institutional Analysis ◽  
Long Term Outcomes ◽  
Prognostic Utility ◽  
Short And Long Term

Impact of major vascular resection on short- and long-term outcomes in patients with intrahepatic cholangiocarcinoma.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 275-275
Author(s):  
Bradley Reames ◽  
Timothy M. Pawlik ◽  
Aslam Ejaz ◽  
Hugo Marques ◽  
Luca Aldrighetti ◽  
...  
Keyword(s):  
Intrahepatic Cholangiocarcinoma ◽  
Major Complication ◽  
Vascular Resection ◽  
Perioperative Outcomes ◽  
Vascular Involvement ◽  
Long Term Outcomes ◽  
Short And Long Term ◽  
Vein Resection ◽  
The Impact

275 Background: Major vascular (IVC or portal vein) resection for Intrahepatic Cholangiocarcinoma (ICC) has traditionally been considered a relative contraindication to resection. We sought to define perioperative outcomes and survival of ICC patients undergoing liver surgery with major vascular resection using a multi-institutional database. Methods: 1,087 ICC patients who underwent liver resection between 1990-2016 were identified from 13 participating institutions. Multivariable logistic and cox regressions were used to determine the impact of major vascular resection on perioperative outcomes and long-term overall survival. Results: Of 1,087 patients who underwent resection, 128(11.8%) also underwent major vascular resection [21(16.4%)IVC resections, 98(76.6%)PV resections, 9(7.0%)combined resections]. One hundred eighty-seven(17.2%) patients received neoadjuvant therapy. Most patients underwent a major hepatectomy involving ≥ 3 liver segments(n = 664,61.1%). On final pathology, the majority of patients had T1(40.4%) or T2(35.5%) tumors; 194(17.8%) had lymph node metastasis. Patients undergoing major vascular resection had more advanced T3/T4 tumors [44(34.4%) vs. 137(14.3%) without resection;P < 0.001]. Of note, major vascular resection was not associated with the risk of any complication (OR .680,95%CI 0.32-1.45) or major complication (OR 0.69,95%CI 0.35-1.33); post-operative mortality was also comparable between groups (OR 1.06, 95%CI 0.32-3.48). In addition, median recurrence-free (14.0 months vs.14.7 months, HR.737,95%CI .49-1.10) and overall (33.4 months vs.40.2 months, HR .709,95%CI.36-1.40) survival were similar among patients who did and did not undergo major vascular resection, respectively(both P > 0.05). Conclusions: Among patients with ICC, major vascular resection was not associated with increased peri-operative morbidity or mortality at major centers. Long-term outcomes following resection of ICC requiring vascular resection were also comparable to outcomes following resection of tumors without vascular involvement. Concurrent major vascular resection should be considered in appropriately selected ICC patients.

scholarly journals Short- and long-term outcomes after laparoscopic and open hepatic resection: systematic review and meta-analysis

HPB ◽  
2011 ◽  
Vol 13 (5) ◽  
pp. 295-308 ◽  
Author(s):  
Reza Mirnezami ◽  
Alexander H. Mirnezami ◽  
Kandiah Chandrakumaran ◽  
Mohammad Abu Hilal ◽  
Neil W. Pearce ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hepatic Resection ◽  
Meta Analysis ◽  
Long Term Outcomes ◽  
Short And Long Term

Short- and Long-Term Outcomes of Liver Resection for Intrahepatic Cholangiocarcinoma Associated with the Metabolic Syndrome

2019 ◽  
Vol 43 (8) ◽  
pp. 2048-2060 ◽  
Author(s):  
Christian Hobeika ◽  
François Cauchy ◽  
Nicolas Poté ◽  
Pierre-Emmanuel Rautou ◽  
François Durand ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Resection ◽  
Intrahepatic Cholangiocarcinoma ◽  
Long Term Outcomes ◽  
The Metabolic Syndrome ◽  
Short And Long Term
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